DK0910642T3 - Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi - Google Patents

Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi

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Publication number
DK0910642T3
DK0910642T3 DK97928925T DK97928925T DK0910642T3 DK 0910642 T3 DK0910642 T3 DK 0910642T3 DK 97928925 T DK97928925 T DK 97928925T DK 97928925 T DK97928925 T DK 97928925T DK 0910642 T3 DK0910642 T3 DK 0910642T3
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DK
Denmark
Prior art keywords
hemoprotein
fungal cell
filamentous fungal
nucleic acid
increasing
Prior art date
Application number
DK97928925T
Other languages
Danish (da)
English (en)
Inventor
Susan L Elrod
Joel R Cherry
Aubrey Jones
Original Assignee
Novozymes Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Biotech Inc filed Critical Novozymes Biotech Inc
Application granted granted Critical
Publication of DK0910642T3 publication Critical patent/DK0910642T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0065Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0069Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97928925T 1996-06-10 1997-06-09 Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi DK0910642T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66275296A 1996-06-10 1996-06-10
US4115897P 1997-03-17 1997-03-17
PCT/US1997/010003 WO1997047746A1 (en) 1996-06-10 1997-06-09 A method for increasing hemoprotein production in filamentous fungi

Publications (1)

Publication Number Publication Date
DK0910642T3 true DK0910642T3 (da) 2004-08-09

Family

ID=26717857

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97928925T DK0910642T3 (da) 1996-06-10 1997-06-09 Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi

Country Status (9)

Country Link
US (2) US6100057A (de)
EP (1) EP0910642B1 (de)
JP (1) JP3462218B2 (de)
CN (1) CN1267556C (de)
AT (1) ATE265534T1 (de)
AU (1) AU3307797A (de)
DE (1) DE69728878T2 (de)
DK (1) DK0910642T3 (de)
WO (1) WO1997047746A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047746A1 (en) * 1996-06-10 1997-12-18 Novo Nordisk Biotech, Inc. A method for increasing hemoprotein production in filamentous fungi
WO1997047753A1 (en) * 1996-06-10 1997-12-18 Novo Nordisk Biotech, Inc. Aspergillus porphobilinogen synthases and nucleic acids encoding same
ATE288491T1 (de) * 1997-11-17 2005-02-15 Novozymes Biotech Inc Polypeptide mit 5-aminolevulinsäure synthaseaktivität und deren nukleinsäuren
US6033892A (en) * 1998-11-16 2000-03-07 Novo Nordis Biotech, Inc. Polypeptides having 5-aminolevulinic acid synthase activity and nucleic acids encoding same
CN1279719A (zh) * 1997-11-17 2001-01-10 诺沃诺尔迪斯克生物技术有限公司 具有尿卟啉原脱羧酶活性的多肽和编码该多肽的核酸
AU1807899A (en) * 1997-12-08 1999-06-28 Novo Nordisk Biotech, Inc. Methods for increasing hemoprotein production in fungal mutants
EP2119773A1 (de) 2000-06-26 2009-11-18 Novozymes A/S Lipolytische Enzyme aus Fusarium und Acremonium Stämmen
DE60331644D1 (de) 2002-04-22 2010-04-22 Novozymes Inc Verfahren zur herstellung von varianten einer dna-sequenz in filamentösen pilzen
AU2003231028A1 (en) 2002-04-22 2003-11-03 Novozymes Biotech, Inc. Methods for increasing homologous recombination of a nucleic acid sequence
US7183091B2 (en) * 2003-02-19 2007-02-27 Nugen Bioscience (Taiwan) Co., Ltd. Sulfite reductase, the process for producing the same and the use thereof
US20050089972A1 (en) * 2003-08-01 2005-04-28 Claudia Schmidt-Dannert Production of porphyrins
RU2728653C2 (ru) 2014-03-31 2020-07-30 Импоссибл Фудз Инк. Аналоги мясного фарша
NZ737094A (en) 2015-05-11 2019-06-28 Impossible Foods Inc Expression constructs and methods of genetically engineering methylotrophic yeast
JP6615525B2 (ja) * 2015-07-30 2019-12-04 シスメックス株式会社 ヘムタンパク質の生産方法
CN105483147B (zh) * 2016-01-22 2019-05-03 吉林大学 一种与致病力相关的灰霉病菌基因BcUdc1及其应用
CN108251441A (zh) * 2017-12-28 2018-07-06 广州天宝颂原生物科技开发有限公司 一种链亲和素融合光敏色素的荧光标记物的制备方法
CN114341351A (zh) 2019-04-25 2022-04-12 非凡食品有限公司 用于产生含血红素蛋白的菌株和方法
WO2023039012A1 (en) * 2021-09-07 2023-03-16 The Regents Of The University Of California Expression of heme biosynthesis and heme proteins in edible filamentous fungi
US20230340077A1 (en) * 2021-12-01 2023-10-26 Luyef Biotechnologies Inc. Production of myoglobin from trichoderma using a feeding media

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88095A0 (en) * 1987-10-23 1989-06-30 California Inst Of Techn Dna sequences,proteins and gene preparations
NZ242074A (en) * 1991-03-22 1993-08-26 Novo Nordisk As Extracellular production of a heterologous heme protein in a filamentous fungus; dna construct therefor
WO1993025697A1 (en) * 1992-06-15 1993-12-23 California Institute Of Technology Enhancement of cell growth by expression of cloned oxygen-binding proteins
US5824511A (en) * 1995-08-01 1998-10-20 University Technology Corporation Method for enhancing the production of hemoproteins
WO1997047746A1 (en) * 1996-06-10 1997-12-18 Novo Nordisk Biotech, Inc. A method for increasing hemoprotein production in filamentous fungi

Also Published As

Publication number Publication date
EP0910642A1 (de) 1999-04-28
ATE265534T1 (de) 2004-05-15
CN1221453A (zh) 1999-06-30
DE69728878T2 (de) 2005-04-07
JP2000512151A (ja) 2000-09-19
CN1267556C (zh) 2006-08-02
AU3307797A (en) 1998-01-07
US6100057A (en) 2000-08-08
JP3462218B2 (ja) 2003-11-05
DE69728878D1 (de) 2004-06-03
WO1997047746A1 (en) 1997-12-18
US6261827B1 (en) 2001-07-17
EP0910642B1 (de) 2004-04-28

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