DK0906301T3 - Benzofurylderivater og anvendelsen deraf - Google Patents

Benzofurylderivater og anvendelsen deraf

Info

Publication number
DK0906301T3
DK0906301T3 DK97921737T DK97921737T DK0906301T3 DK 0906301 T3 DK0906301 T3 DK 0906301T3 DK 97921737 T DK97921737 T DK 97921737T DK 97921737 T DK97921737 T DK 97921737T DK 0906301 T3 DK0906301 T3 DK 0906301T3
Authority
DK
Denmark
Prior art keywords
benzofuryl
derivatives
benzofuryl derivatives
Prior art date
Application number
DK97921737T
Other languages
Danish (da)
English (en)
Inventor
Michael Boes
Heinz Stadler
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0906301T3 publication Critical patent/DK0906301T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
DK97921737T 1996-05-03 1997-04-24 Benzofurylderivater og anvendelsen deraf DK0906301T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96106990 1996-05-03
PCT/EP1997/002092 WO1997042183A1 (en) 1996-05-03 1997-04-24 Benzofuryl derivatives and their use

Publications (1)

Publication Number Publication Date
DK0906301T3 true DK0906301T3 (da) 2003-02-10

Family

ID=8222741

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97921737T DK0906301T3 (da) 1996-05-03 1997-04-24 Benzofurylderivater og anvendelsen deraf

Country Status (21)

Country Link
US (1) US5955495A (xx)
EP (1) EP0906301B1 (xx)
JP (1) JP3148253B2 (xx)
KR (1) KR100343060B1 (xx)
CN (1) CN100347164C (xx)
AR (1) AR006915A1 (xx)
AT (1) ATE225342T1 (xx)
AU (1) AU712056B2 (xx)
BR (1) BR9708902A (xx)
CA (1) CA2253547C (xx)
CO (1) CO4940471A1 (xx)
DE (1) DE69716062T2 (xx)
DK (1) DK0906301T3 (xx)
ES (1) ES2182070T3 (xx)
HR (1) HRP970225A2 (xx)
MA (1) MA24168A1 (xx)
PE (1) PE64698A1 (xx)
PT (1) PT906301E (xx)
TR (1) TR199802206T2 (xx)
WO (1) WO1997042183A1 (xx)
ZA (1) ZA973708B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2786184B1 (fr) * 1998-11-24 2002-09-20 Hoechst Marion Roussel Inc Nouveaux derives du benzofurane, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
HUP0303316A2 (hu) 2000-12-20 2004-01-28 Bristol-Myers Squibb Pharma Company Aril- és amino-aril-szubsztituált szerotoninreceptor agonista és antagonista ligandumok és ezeket tartalmazó gyógyszerkészítmények
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
AU2003216954A1 (en) * 2002-03-29 2003-10-13 Orion Corporation Treatment of dependence and dependence related withdrawal symptoms
FR2845992B1 (fr) * 2002-10-16 2005-02-04 Pf Medicament Derives de 3-(cyclopenten-1yl)-benzyl-ou3-(cyclopenten-1yl)- heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie
DE10257357A1 (de) 2002-12-09 2004-06-24 Bayer Ag Fluorhaltige Benzaldehyde
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US20050215644A1 (en) * 2004-03-19 2005-09-29 Interhealth Nutraceuticals, Inc. Methods for increasing neurotransmitter levels using hydroxycitric acid
EP2400300A1 (en) 2004-08-25 2011-12-28 Takeda Pharmaceutical Company Limited Method of screening preventives/remedies for stress urinary incontinence
WO2006122150A1 (en) 2005-05-10 2006-11-16 Incyte Corporation Modulators of indoleamine 2,3-dioxygenase and methods of using the same
EP1971583B1 (en) 2005-12-20 2015-03-25 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
EP2018863B9 (en) 2006-05-16 2015-02-18 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
JP5319532B2 (ja) 2006-09-19 2013-10-16 インサイト・コーポレイション インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル
US20100286415A1 (en) * 2007-05-29 2010-11-11 Osaka Bioscience Institute Sleep-improving agent
EP2216023A4 (en) 2007-11-15 2013-03-13 Takeda Pharmaceutical CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF
LT2824100T (lt) 2008-07-08 2018-05-10 Incyte Holdings Corporation 1,2,5-oksadiazolai, kaip indolamino 2,3-dioksigenazės inhibitoriai
UY32940A (es) * 2009-10-27 2011-05-31 Bayer Cropscience Ag Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
CN104045631A (zh) * 2013-03-13 2014-09-17 无锡万全医药技术有限公司 一种制备5-(4-(4-(5-氰基-1h-吲哚-3-基)丁基)哌嗪-1-基)苯并呋喃-2-甲酰胺的新方法
CN103360374B (zh) * 2013-07-12 2016-03-09 苏州永健生物医药有限公司 维拉唑酮及其盐的合成方法
AR098343A1 (es) 2013-11-08 2016-05-26 Incyte Holdings Corp Proceso para la síntesis de un inhibidor de indolamina 2,3-dioxigenasa
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces
CN114315773B (zh) * 2020-09-29 2024-01-16 广东东阳光药业股份有限公司 一种哌嗪化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68901424D1 (de) * 1988-07-05 1992-06-11 Akzo Nv Verbindungen mit bronchodilatatorischer aktivitaet.
US5026726A (en) * 1989-12-11 1991-06-25 The University Of New Mexico Gossylic iminolactones and gossylic lactones and their anti-viral activities

Also Published As

Publication number Publication date
BR9708902A (pt) 1999-08-03
PT906301E (pt) 2003-02-28
CN100347164C (zh) 2007-11-07
ES2182070T3 (es) 2003-03-01
HRP970225A2 (en) 1998-04-30
AU2769697A (en) 1997-11-26
DE69716062D1 (de) 2002-11-07
EP0906301A1 (en) 1999-04-07
ATE225342T1 (de) 2002-10-15
JP3148253B2 (ja) 2001-03-19
MA24168A1 (fr) 1997-12-31
AR006915A1 (es) 1999-09-29
CA2253547A1 (en) 1997-11-13
AU712056B2 (en) 1999-10-28
CA2253547C (en) 2006-10-17
PE64698A1 (es) 1998-10-27
US5955495A (en) 1999-09-21
DE69716062T2 (de) 2003-06-18
EP0906301B1 (en) 2002-10-02
CO4940471A1 (es) 2000-07-24
KR100343060B1 (ko) 2002-09-18
WO1997042183A1 (en) 1997-11-13
CN1217720A (zh) 1999-05-26
ZA973708B (en) 1997-11-03
JPH11508283A (ja) 1999-07-21
TR199802206T2 (xx) 2001-12-21
KR20000010708A (ko) 2000-02-25

Similar Documents

Publication Publication Date Title
DK0906301T3 (da) Benzofurylderivater og anvendelsen deraf
NO984354D0 (no) Avisingsmiddel og anvendelse av dette
IS4481A (is) Díhýdrópyramídín og notkun þeirra
DK0815861T3 (da) Sulfonamider og anvendelse deraf
DK1454907T3 (da) Quninazolin og pyridopyrmidin-derivativer
DK0915880T3 (da) Azolotriaziner og pyrimidiner
NO961425D0 (no) 1N-alkyl-N-arylpyrimidinaminer og derivater derav
NO990700L (no) Propionsyrederivater og anvendelsen herav
ATE225784T1 (de) Indan- oder dihydroindolderivate
NO983235D0 (no) Fikstur og protese innbefattende samme
SG91796A1 (en) N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their use
DK0804078T3 (da) Sammensætning og anvendelse deraf
NO975439D0 (no) Ketonderivater og medisinsk anvendelse derav
BR9506832A (pt) N-pirazolilanilinas e n-pirazolilaminopiridinas
TR199800117A3 (tr) Isaksazol- ve krotonasitamid türevleri ve bunlarin kullanimi.
EE03563B1 (et) Alküülaminobensotiasooli ja -bensoksasooli derivaadid
NO986174D0 (no) Triazinderivater og anvendelse derav
NO972206D0 (no) Bjelke og karosserikonstruksjon
NO964541L (no) Porphacyanin og CNC-utvidete porphyriner
DK1140952T3 (da) Phosphororganiske forbindelser og anvendelse heraf
DE69721846D1 (de) Hosenträger
NO984921D0 (no) Tienopyridinderivater og deres anvendelse
NO20003268D0 (no) Hyperhydrert kitikolin, fremgangsmÕte og anvendelse
NO983556L (no) Formulering og anvendelse
NO985928D0 (no) 19Fluor merket antracyklinon og antracyklinderivater