DK0874852T3 - Antibakterielt oxazolidinonmiddel med tricykliske substituenter - Google Patents

Antibakterielt oxazolidinonmiddel med tricykliske substituenter

Info

Publication number
DK0874852T3
DK0874852T3 DK96939496T DK96939496T DK0874852T3 DK 0874852 T3 DK0874852 T3 DK 0874852T3 DK 96939496 T DK96939496 T DK 96939496T DK 96939496 T DK96939496 T DK 96939496T DK 0874852 T3 DK0874852 T3 DK 0874852T3
Authority
DK
Denmark
Prior art keywords
antibacterial oxazolidinone
organisms
oxazolidinone agent
tricyclic substituents
tricyclic
Prior art date
Application number
DK96939496T
Other languages
Danish (da)
English (en)
Inventor
Richard C Thomas
Gary J Cleek
Douglas K Hutchinson
Hiroyoshi Yamada
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DK0874852T3 publication Critical patent/DK0874852T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK96939496T 1995-11-17 1996-11-05 Antibakterielt oxazolidinonmiddel med tricykliske substituenter DK0874852T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US737195P 1995-11-17 1995-11-17
PCT/US1996/017120 WO1997019089A1 (fr) 1995-11-17 1996-11-05 Agent anti-bacterien a base d'oxazolidinone a substituants tricycliques

Publications (1)

Publication Number Publication Date
DK0874852T3 true DK0874852T3 (da) 2004-06-07

Family

ID=21725778

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96939496T DK0874852T3 (da) 1995-11-17 1996-11-05 Antibakterielt oxazolidinonmiddel med tricykliske substituenter

Country Status (12)

Country Link
US (2) US5922707A (fr)
EP (1) EP0874852B1 (fr)
JP (1) JP2000500489A (fr)
AT (1) ATE263172T1 (fr)
AU (1) AU7665196A (fr)
DE (1) DE69632074T2 (fr)
DK (1) DK0874852T3 (fr)
ES (1) ES2217329T3 (fr)
PT (1) PT874852E (fr)
TW (1) TW426683B (fr)
WO (1) WO1997019089A1 (fr)
ZA (1) ZA968661B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
ID23803A (id) * 1997-08-15 2000-05-11 Pfizer Prod Inc Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
DE19802235A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Mit tricyclischen Indolen substituierte Oxazolidinone
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
EP1049682A1 (fr) 1998-01-23 2000-11-08 Versicor, Inc. Banques combinatoires d'oxazolidinones, compositions a base de tels composes et procedes de preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
DE19805117A1 (de) * 1998-02-09 1999-08-12 Bayer Ag Neue Oxazolidinone mit azolhaltigen Tricyclen
TR200003595T2 (tr) * 1998-06-05 2001-07-23 Astrazeneca Ab Kimyasal bileşikler
MY122454A (en) * 1998-06-05 2006-04-29 Upjohn Co Use of oxazolidinones for the preparation of a medicament for transdermal delivery
ES2300151T3 (es) 1998-09-22 2008-06-01 Astellas Pharma Inc. Derivados de cianofenilo.
JP2002535680A (ja) 1999-01-27 2002-10-22 ファルマシア・アンド・アップジョン・カンパニー 延長因子ｐ活性モジュレーターのアッセイ方法
JP2003501351A (ja) * 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
EP1539745B1 (fr) 2002-08-12 2006-03-29 Pharmacia & Upjohn Company LLC N-aryl-2-oxazolidinones et leurs derives
BR0316483A (pt) 2002-11-21 2005-10-11 Upjohn Co Derivados de n-(4-(piperazin-1-il)-fenil-2-oxazolidinona-5-carboxami da e compostos relacionados como agentes antibacterianos
EP1594865A2 (fr) * 2003-02-07 2005-11-16 Warner-Lambert Company LLC Agents antibacteriens
US7795267B2 (en) * 2003-08-29 2010-09-14 Takeda Pharmaceutical Company Limited Bicyclic piperazine compound having TGR23 antagonistic activity
AR057828A1 (es) * 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
WO2007087250A2 (fr) 2006-01-23 2007-08-02 Amira Pharmaceuticals, Inc. Inhibiteurs tricycliques de la 5-lipoxygenase
CN110734454B (zh) * 2016-12-12 2021-08-17 石药集团中奇制药技术（石家庄）有限公司 一类含有三环杂芳基的化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883522A (en) * 1974-02-11 1975-05-13 Riker Laboratories Inc Substituted pyrido(1,2,3-de)-1,4-benzoxazines
US4080499A (en) * 1976-12-20 1978-03-21 1 Substituted 7,8-dihydro-6H-(1,2,5)thiadiazolo(3',4'-5,6)pyrazino(2,3-b)(1,4)oxazines
US5039690A (en) * 1987-10-09 1991-08-13 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
DE68929303T2 (de) * 1988-09-15 2002-05-02 Pharmacia & Upjohn Co., Kalamazoo 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
ES2177539T3 (es) * 1992-02-13 2002-12-16 Upjohn Co Benzoxacinas 4-oxo- y 4h-imidazo(5,1-c)(1,4) utilez como agentes de union de receptores de benzodiacepina.
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
ES2193201T3 (es) * 1994-11-15 2003-11-01 Upjohn Co Agentes antibacterianos tipo oxazolidonas sustituidas con oxazina y tiazina biciclica.
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.

Also Published As

Publication number Publication date
DE69632074T2 (de) 2005-01-20
TW426683B (en) 2001-03-21
ZA968661B (en) 1998-04-14
US5922707A (en) 1999-07-13
DE69632074D1 (de) 2004-05-06
US5955460A (en) 1999-09-21
WO1997019089A1 (fr) 1997-05-29
PT874852E (pt) 2004-08-31
AU7665196A (en) 1997-06-11
EP0874852B1 (fr) 2004-03-31
ES2217329T3 (es) 2004-11-01
ATE263172T1 (de) 2004-04-15
EP0874852A1 (fr) 1998-11-04
JP2000500489A (ja) 2000-01-18

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