DK0874841T3 - 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren - Google Patents

1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren

Info

Publication number
DK0874841T3
DK0874841T3 DK96943182T DK96943182T DK0874841T3 DK 0874841 T3 DK0874841 T3 DK 0874841T3 DK 96943182 T DK96943182 T DK 96943182T DK 96943182 T DK96943182 T DK 96943182T DK 0874841 T3 DK0874841 T3 DK 0874841T3
Authority
DK
Denmark
Prior art keywords
benzenesulfonylpyrrolidine
antagonists
derivatives
bradykinin receptor
alkyl group
Prior art date
Application number
DK96943182T
Other languages
Danish (da)
English (en)
Inventor
Pierre Dodey
Michel Bondoux
Patrick Houziaux
Martine Barth
Khan Ou
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Application granted granted Critical
Publication of DK0874841T3 publication Critical patent/DK0874841T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK96943182T 1995-12-29 1996-12-23 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren DK0874841T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9515706A FR2743073B1 (fr) 1995-12-29 1995-12-29 Nouveaux composes de 1-benzenesulfonylpyrrolidine, procede de preparation et utilisation en therapeutique
PCT/FR1996/002066 WO1997024349A1 (fr) 1995-12-29 1996-12-23 Derives de 1-benzenesulfonylpyrrolidine comme antagonistes du recepteur de la bradykinine

Publications (1)

Publication Number Publication Date
DK0874841T3 true DK0874841T3 (da) 2002-01-28

Family

ID=9486120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96943182T DK0874841T3 (da) 1995-12-29 1996-12-23 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren

Country Status (11)

Country Link
US (1) US6211181B1 (ja)
EP (1) EP0874841B1 (ja)
JP (1) JP2000502693A (ja)
AT (1) ATE206418T1 (ja)
AU (1) AU1198897A (ja)
DE (1) DE69615707T2 (ja)
DK (1) DK0874841T3 (ja)
ES (1) ES2167617T3 (ja)
FR (1) FR2743073B1 (ja)
PT (1) PT874841E (ja)
WO (1) WO1997024349A1 (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751650B1 (fr) * 1996-07-24 1998-10-09 Fournier Ind & Sante Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique
IL128666A (en) * 1996-08-28 2005-09-25 Procter & Gamble Substituted cyclic amine metalloprotease inhibitors
US6872742B2 (en) 1996-08-28 2005-03-29 The Procter & Gamble Company Substituted cyclic amine metalloprotease inhibitors
KR100352316B1 (ko) 1997-07-31 2002-09-12 더 프록터 앤드 갬블 캄파니 메탈로프로테아제억제제로서사용되는술포닐아미노치환히드록삼산유도체
FR2790260B1 (fr) * 1999-02-26 2001-05-04 Fournier Ind & Sante Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique
KR20010102486A (ko) 1999-03-03 2001-11-15 데이비드 엠 모이어 알케닐- 및 알키닐-함유 메탈로프로테아제 저해제
JP2003505384A (ja) 1999-07-15 2003-02-12 ファーマコピーア，インコーポレーティッド ブラジキニンｂ１受容体アンタゴニスト
CA2364178C (en) * 2000-12-05 2006-01-10 Yasuhiro Katsu N-benzenesulfonyl l-proline compounds as bradykinin antagonists
FR2819254B1 (fr) * 2001-01-08 2003-04-18 Fournier Lab Sa Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques
EP1914236A1 (en) 2002-04-10 2008-04-23 Ortho-McNeil Pharmaceutical, Inc. Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators
FR2840897B1 (fr) 2002-06-14 2004-09-10 Fournier Lab Sa Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique
WO2004087700A1 (fr) 2003-03-25 2004-10-14 Laboratoires Fournier S.A. Derives du benzenesulfonamide, leur procede de preparation et leur utilisation de la douleur
AU2013226013B2 (en) * 2012-02-29 2016-08-11 Baruch S. Blumberg Institute Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation and Their Method of Use
WO2016170382A1 (en) 2015-04-23 2016-10-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Pharmaceutical compositions comprising a bradykinin 2 receptor antagonist for prevention or treatment of impaired skin wound healing

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3632329A1 (de) 1986-09-24 1988-03-31 Bayer Ag Substituierte phenylsulfonamide
US5288725A (en) * 1992-10-15 1994-02-22 Merck & Co., Inc. Pyrroloquinoline Bradykinin antagonist
AU686115B2 (en) 1992-11-02 1998-02-05 Fujisawa Pharmaceutical Co., Ltd. Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation
AU680870B2 (en) * 1993-04-28 1997-08-14 Astellas Pharma Inc. New heterocyclic compounds

Also Published As

Publication number Publication date
WO1997024349A1 (fr) 1997-07-10
DE69615707T2 (de) 2002-08-08
FR2743073A1 (fr) 1997-07-04
FR2743073B1 (fr) 1998-02-20
EP0874841A1 (fr) 1998-11-04
AU1198897A (en) 1997-07-28
PT874841E (pt) 2002-03-28
ATE206418T1 (de) 2001-10-15
US6211181B1 (en) 2001-04-03
DE69615707D1 (de) 2001-11-08
EP0874841B1 (fr) 2001-10-04
ES2167617T3 (es) 2002-05-16
JP2000502693A (ja) 2000-03-07

Similar Documents

Publication Publication Date Title
DK0874841T3 (da) 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren
BRPI0000596B8 (pt) composto piridona, processo de produção do composto, composição farmacêutica, e uso do dito composto
ID21538A (id) Turunan anilida, produksi dan pemakaiannya
DK0931083T3 (da) Fremgangsmåde til fremstilling af ecteinascidinforbindelser
ATE315567T1 (de) A-1-adenosin rezeptor antagoniste
DE69524251T2 (de) Neue verbindung, verfahren zu ihrer herstellung und antitumormittel
DK142084A (da) N-phenyl-n'-cycloalkylalkanoyl-piperaziner og fremgangsmaade til fremstilling heraf
DK0807633T3 (da) Hidtil ukendte 2,3-disubstituerede-(5,6)-heteroarylkondenserede pyrimidin-4-oner
DE69808619D1 (de) Prostaglandin-pharmazeutische-zusammensetzungen
DK0918776T3 (da) Totalsyntese af antitumor acylfulvener
EA200000336A1 (ru) Антагонисты рецептора витронектина
DE69424039D1 (de) Neue verbindungen
DK0594263T3 (da) Mellemprodukter til fremstilling af thioalkylthio-cephalosporinderivater
DK0902018T3 (da) 2-(arylpheny)amino-imidazolinderivater
EA200100090A3 (ru) Новые пиперидин-4-сульфонамидные производные, способ их получения и содержащие их фармацевтические композиции
BR0112043A (pt) Ftalidas substituìdas, processo para sua preparação e composições farmacêuticas contendo-as
CY1105550T1 (el) Μεμνο-πεπτιδια, μια διαδικασια για την παρασκευη και τη χρηση τους
BR0213465A (pt) Compostos de 4-imidazolin-2-ona
NO963331L (no) 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister
ATE256110T1 (de) Piperindinverbindungen als calcium-kanal-blocker
ATE228520T1 (de) Lactamverbindungen als inhibitoren der cholesterin-esterase
ID25477A (id) Turunan-turunan spiropiperidin
DK1206452T3 (da) Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser
DK1347960T3 (da) Fremgangsmåde til fremstilling af (+/-) trans-4-p-fluorphenyl-3-hydromethyl-1-methylpiperidin
NO980145L (no) Polyucykliske alkaloid-derivater som NMDA-reseptor-antagonister