DK0874819T3 - Imider som PDE III-, PDE IV- og TNF-inhibitorer - Google Patents

Imider som PDE III-, PDE IV- og TNF-inhibitorer

Info

Publication number
DK0874819T3
DK0874819T3 DK96945277T DK96945277T DK0874819T3 DK 0874819 T3 DK0874819 T3 DK 0874819T3 DK 96945277 T DK96945277 T DK 96945277T DK 96945277 T DK96945277 T DK 96945277T DK 0874819 T3 DK0874819 T3 DK 0874819T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
alkoxy
unsubstituted
substituted
carbon atoms
Prior art date
Application number
DK96945277T
Other languages
Danish (da)
English (en)
Inventor
George W Muller
Mary Shire
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Application granted granted Critical
Publication of DK0874819T3 publication Critical patent/DK0874819T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK96945277T 1995-12-26 1996-12-24 Imider som PDE III-, PDE IV- og TNF-inhibitorer DK0874819T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/578,738 US5728844A (en) 1995-08-29 1995-12-26 Immunotherapeutic agents

Publications (1)

Publication Number Publication Date
DK0874819T3 true DK0874819T3 (da) 2004-09-06

Family

ID=24314105

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04076505T DK1468991T3 (da) 1995-12-26 1996-12-24 Imider som PDE III-, PDE IV og TNF-inhibitorer
DK96945277T DK0874819T3 (da) 1995-12-26 1996-12-24 Imider som PDE III-, PDE IV- og TNF-inhibitorer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK04076505T DK1468991T3 (da) 1995-12-26 1996-12-24 Imider som PDE III-, PDE IV og TNF-inhibitorer

Country Status (22)

Country Link
US (1) US5728844A (de)
EP (2) EP1468991B1 (de)
JP (1) JP4159109B2 (de)
KR (1) KR100450005B1 (de)
CN (1) CN1092640C (de)
AT (2) ATE386719T1 (de)
AU (1) AU723331B2 (de)
CA (1) CA2241688A1 (de)
CZ (1) CZ299090B6 (de)
DE (2) DE69632595T2 (de)
DK (2) DK1468991T3 (de)
ES (2) ES2303019T3 (de)
FI (1) FI981437A (de)
HK (2) HK1017620A1 (de)
HU (1) HUP9901780A3 (de)
IL (1) IL125086A (de)
NZ (1) NZ326578A (de)
PL (1) PL327585A1 (de)
PT (2) PT874819E (de)
RU (1) RU2174512C2 (de)
SK (1) SK88898A3 (de)
WO (1) WO1997023457A1 (de)

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Also Published As

Publication number Publication date
NZ326578A (en) 1999-10-28
WO1997023457A1 (en) 1997-07-03
CA2241688A1 (en) 1997-07-03
CZ299090B6 (cs) 2008-04-23
ATE386719T1 (de) 2008-03-15
HK1017620A1 (en) 1999-11-26
RU2174512C2 (ru) 2001-10-10
FI981437A (fi) 1998-08-25
SK88898A3 (en) 1998-12-02
DE69632595T2 (de) 2005-06-23
ES2303019T3 (es) 2008-08-01
HK1072250A1 (en) 2005-08-19
CZ202598A3 (cs) 2000-01-12
US5728844A (en) 1998-03-17
DK1468991T3 (da) 2008-06-16
PT874819E (pt) 2004-10-29
AU1468597A (en) 1997-07-17
DE69632595D1 (de) 2004-07-01
ATE267806T1 (de) 2004-06-15
JP4159109B2 (ja) 2008-10-01
AU723331B2 (en) 2000-08-24
PL327585A1 (en) 1998-12-21
DE69637444T2 (de) 2009-03-05
EP1468991A1 (de) 2004-10-20
HUP9901780A2 (hu) 1999-10-28
KR100450005B1 (ko) 2005-01-15
FI981437A0 (fi) 1996-12-24
KR19990076785A (ko) 1999-10-15
IL125086A (en) 2002-11-10
CN1206405A (zh) 1999-01-27
EP1468991B1 (de) 2008-02-20
IL125086A0 (en) 1999-01-26
CN1092640C (zh) 2002-10-16
PT1468991E (pt) 2008-05-16
DE69637444D1 (de) 2008-04-03
ES2222487T3 (es) 2005-02-01
JP2000502350A (ja) 2000-02-29
EP0874819B1 (de) 2004-05-26
HUP9901780A3 (en) 2001-01-29
EP0874819A1 (de) 1998-11-04

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