DK0862453T3 - Knoglemorfogenprotein-og fibroblastvækstfaktorpræparater og fremgangsmåder til induktion af cardiogenese - Google Patents

Knoglemorfogenprotein-og fibroblastvækstfaktorpræparater og fremgangsmåder til induktion af cardiogenese

Info

Publication number
DK0862453T3
DK0862453T3 DK97936493T DK97936493T DK0862453T3 DK 0862453 T3 DK0862453 T3 DK 0862453T3 DK 97936493 T DK97936493 T DK 97936493T DK 97936493 T DK97936493 T DK 97936493T DK 0862453 T3 DK0862453 T3 DK 0862453T3
Authority
DK
Denmark
Prior art keywords
growth factor
fibroblast growth
methods
bone morphogenic
morphogenic protein
Prior art date
Application number
DK97936493T
Other languages
English (en)
Inventor
John W Lough Jr
Matthew R Barron
Michele A Brogley
Xiaolei Zhu
John E Baker
Original Assignee
Mcw Res Found Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcw Res Found Inc filed Critical Mcw Res Found Inc
Application granted granted Critical
Publication of DK0862453T3 publication Critical patent/DK0862453T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97936493T 1996-08-16 1997-08-13 Knoglemorfogenprotein-og fibroblastvækstfaktorpræparater og fremgangsmåder til induktion af cardiogenese DK0862453T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2406296P 1996-08-16 1996-08-16

Publications (1)

Publication Number Publication Date
DK0862453T3 true DK0862453T3 (da) 2006-08-14

Family

ID=21818673

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97936493T DK0862453T3 (da) 1996-08-16 1997-08-13 Knoglemorfogenprotein-og fibroblastvækstfaktorpræparater og fremgangsmåder til induktion af cardiogenese

Country Status (10)

Country Link
EP (1) EP0862453B1 (da)
JP (1) JP3176377B2 (da)
AT (1) ATE322282T1 (da)
AU (1) AU725084B2 (da)
CA (1) CA2235025C (da)
DE (1) DE69735622T2 (da)
DK (1) DK0862453T3 (da)
ES (1) ES2262185T3 (da)
PT (1) PT862453E (da)
WO (1) WO1998006420A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU741350B2 (en) * 1996-12-20 2001-11-29 Curis, Inc. Treatment of mammalian myocardium with morphogen locally, or with morphogenically-treated myogenic precursor cells
JP2002524425A (ja) * 1998-09-04 2002-08-06 サイオス インコーポレイテッド 増殖因子の徐放性投与のためのヒドロゲル組成物
KR20040022448A (ko) * 2001-07-12 2004-03-12 제론 코포레이션 인간 다분화능 줄기 세포로부터 제조된 심근 세포 계통의세포
ATE481978T1 (de) * 2005-01-25 2010-10-15 Five Prime Therapeutics Inc Zusammensetzungen und verfahren zur behandlung von herzkrankheiten
JP5560393B2 (ja) 2005-06-22 2014-07-23 アステリアス バイオセラピューティクス インコーポレイテッド 心筋細胞系列細胞への霊長類多能性幹細胞の分化

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US5071655A (en) * 1990-01-12 1991-12-10 Baylink David J Pharmaceutical combination for treatment of bone-wasting diseases

Also Published As

Publication number Publication date
CA2235025C (en) 2001-10-09
ES2262185T3 (es) 2006-11-16
EP0862453A4 (en) 2000-11-29
JPH11511181A (ja) 1999-09-28
EP0862453B1 (en) 2006-04-05
DE69735622T2 (de) 2007-04-12
DE69735622D1 (de) 2006-05-18
CA2235025A1 (en) 1998-02-19
AU3914997A (en) 1998-03-06
EP0862453A1 (en) 1998-09-09
JP3176377B2 (ja) 2001-06-18
PT862453E (pt) 2006-08-31
AU725084B2 (en) 2000-10-05
WO1998006420A1 (en) 1998-02-19
ATE322282T1 (de) 2006-04-15

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