DK0854927T3 - Humane DNAse I-varianter - Google Patents

Humane DNAse I-varianter

Info

Publication number
DK0854927T3
DK0854927T3 DK96907094T DK96907094T DK0854927T3 DK 0854927 T3 DK0854927 T3 DK 0854927T3 DK 96907094 T DK96907094 T DK 96907094T DK 96907094 T DK96907094 T DK 96907094T DK 0854927 T3 DK0854927 T3 DK 0854927T3
Authority
DK
Denmark
Prior art keywords
variants
human dnase
dnase
human
Prior art date
Application number
DK96907094T
Other languages
Danish (da)
English (en)
Inventor
Robert A Lazarus
Steven Shak
Jana S Ulmer
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1995/002366 external-priority patent/WO1996026278A1/fr
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0854927T3 publication Critical patent/DK0854927T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK96907094T 1995-02-24 1996-02-21 Humane DNAse I-varianter DK0854927T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US1995/002366 WO1996026278A1 (fr) 1995-02-24 1995-02-24 VARIANTES DE LA DNAse I HUMAINE
US54052795A 1995-10-10 1995-10-10
PCT/US1996/002421 WO1996026279A1 (fr) 1995-02-24 1996-02-21 Variantes de dnase i humaine

Publications (1)

Publication Number Publication Date
DK0854927T3 true DK0854927T3 (da) 2008-09-08

Family

ID=26789529

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96907094T DK0854927T3 (da) 1995-02-24 1996-02-21 Humane DNAse I-varianter

Country Status (20)

Country Link
EP (2) EP1980618A2 (fr)
JP (1) JP4549439B2 (fr)
AR (1) AR003926A1 (fr)
AT (1) ATE397073T1 (fr)
AU (1) AU695863B2 (fr)
BR (1) BR9607328A (fr)
CA (1) CA2211413C (fr)
DE (1) DE69637548D1 (fr)
DK (1) DK0854927T3 (fr)
ES (1) ES2308775T3 (fr)
HU (1) HU222665B1 (fr)
IL (1) IL117218A (fr)
NO (1) NO326616B1 (fr)
NZ (1) NZ334762A (fr)
PL (1) PL184951B1 (fr)
RO (1) RO118886B1 (fr)
SI (1) SI9620043A (fr)
SK (1) SK284191B6 (fr)
TR (1) TR199700842T1 (fr)
WO (1) WO1996026279A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391607B1 (en) * 1996-06-14 2002-05-21 Genentech, Inc. Human DNase I hyperactive variants
US20150010527A1 (en) * 2012-02-01 2015-01-08 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
US10988745B2 (en) 2013-10-31 2021-04-27 Resolve Therapeutics, Llc Therapeutic nuclease-albumin fusions and methods
CN104131093B (zh) * 2014-07-23 2015-12-09 哈尔滨工程大学 DNA蛋白结合位点的DNase高通测序检测信号处理方法
EP3240896A1 (fr) 2015-01-04 2017-11-08 Protalix Ltd. Dnase modifiée et ses utilisations
WO2022074656A1 (fr) 2020-10-07 2022-04-14 Protalix Ltd. Dnase à action prolongée

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511502A (en) 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
WO1987005330A1 (fr) 1986-03-07 1987-09-11 Michel Louis Eugene Bergh Procede pour ameliorer la stabilite des glycoproteines
DE68929551T2 (de) 1988-12-23 2008-03-06 Genentech, Inc., South San Francisco Menschliche DNase
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I
US5279823A (en) 1992-06-08 1994-01-18 Genentech, Inc. Purified forms of DNASE
ATE155581T1 (de) 1992-11-02 1997-08-15 Genentech Inc Verdichtungsprüfung zur bewertung einer therapie für eine atmungskrankheit
CA2210871C (fr) * 1995-02-24 2009-04-07 Genentech, Inc. Variantes de la dnase i humaine

Also Published As

Publication number Publication date
EP0854927B1 (fr) 2008-05-28
NO973877L (no) 1997-10-24
AU695863B2 (en) 1998-08-27
ATE397073T1 (de) 2008-06-15
JP4549439B2 (ja) 2010-09-22
SK114897A3 (en) 1998-03-04
BR9607328A (pt) 1997-12-30
SK284191B6 (sk) 2004-10-05
TR199700842T1 (xx) 1998-01-21
WO1996026279A1 (fr) 1996-08-29
PL322002A1 (en) 1998-01-05
HUP9702147A2 (hu) 1999-07-28
RO118886B1 (ro) 2003-12-30
AR003926A1 (es) 1998-09-30
SI9620043A (sl) 1998-06-30
IL117218A0 (en) 1996-06-18
DE69637548D1 (de) 2008-07-10
EP1980618A2 (fr) 2008-10-15
AU5026396A (en) 1996-09-11
NO973877D0 (no) 1997-08-22
PL184951B1 (pl) 2003-01-31
JPH11503004A (ja) 1999-03-23
NZ334762A (en) 2000-10-27
ES2308775T3 (es) 2008-12-01
EP0854927A1 (fr) 1998-07-29
IL117218A (en) 2004-06-01
CA2211413C (fr) 2010-06-22
HUP9702147A3 (en) 1999-09-28
HU222665B1 (hu) 2003-09-29
NO326616B1 (no) 2009-01-19
CA2211413A1 (fr) 1996-08-29

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