DK0820451T3 - Hidtil ukendte heterocykliske forbindelser - Google Patents
Hidtil ukendte heterocykliske forbindelserInfo
- Publication number
- DK0820451T3 DK0820451T3 DK96907327T DK96907327T DK0820451T3 DK 0820451 T3 DK0820451 T3 DK 0820451T3 DK 96907327 T DK96907327 T DK 96907327T DK 96907327 T DK96907327 T DK 96907327T DK 0820451 T3 DK0820451 T3 DK 0820451T3
- Authority
- DK
- Denmark
- Prior art keywords
- heterocyclic compounds
- new heterocyclic
- new
- compounds
- heterocyclic
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK40595 | 1995-04-07 | ||
| DK100595 | 1995-09-11 | ||
| PCT/DK1996/000139 WO1996031498A1 (en) | 1995-04-07 | 1996-04-01 | Novel heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0820451T3 true DK0820451T3 (da) | 2003-05-12 |
Family
ID=26063928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96907327T DK0820451T3 (da) | 1995-04-07 | 1996-04-01 | Hidtil ukendte heterocykliske forbindelser |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5874428A (cs) |
| EP (1) | EP0820451B1 (cs) |
| JP (1) | JPH11503127A (cs) |
| KR (1) | KR100466915B1 (cs) |
| CN (1) | CN1152030C (cs) |
| AR (1) | AR007759A1 (cs) |
| AT (1) | ATE231144T1 (cs) |
| AU (1) | AU708010B2 (cs) |
| CA (1) | CA2217197A1 (cs) |
| CZ (1) | CZ291294B6 (cs) |
| DE (1) | DE69625806T2 (cs) |
| DK (1) | DK0820451T3 (cs) |
| ES (1) | ES2191090T3 (cs) |
| HU (1) | HUP9800719A3 (cs) |
| IL (1) | IL117810A (cs) |
| MX (1) | MX9707531A (cs) |
| NO (1) | NO974605L (cs) |
| PL (1) | PL187171B1 (cs) |
| RU (1) | RU2244713C2 (cs) |
| TW (1) | TW419463B (cs) |
| UA (1) | UA54385C2 (cs) |
| WO (1) | WO1996031498A1 (cs) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6239148B1 (en) * | 1994-01-04 | 2001-05-29 | Novo Nordisk A/S | N-substituted azaheterocyclic carboxylic acids and esters thereof |
| US6281212B1 (en) | 1996-07-12 | 2001-08-28 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6323206B1 (en) | 1996-07-12 | 2001-11-27 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| ZA978792B (en) * | 1996-10-04 | 1998-04-06 | Novo Nordisk As | N-substituted azaheterocyclic compounds. |
| KR20000048899A (ko) * | 1996-10-04 | 2000-07-25 | 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 | 1,4-디치환 피페라진 |
| JP2002508353A (ja) * | 1997-12-17 | 2002-03-19 | ノボ ノルディスク アクティーゼルスカブ | 新規ヘテロ環式化合物 |
| US6048856A (en) * | 1997-12-17 | 2000-04-11 | Novo Nordisk A/S | Heterocyclic compounds |
| AU2335699A (en) | 1998-01-21 | 1999-08-09 | Kyowa Hakko Kogyo Co. Ltd. | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) * | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| CN1289336A (zh) * | 1998-01-21 | 2001-03-28 | 千禧药品公司 | 趋化因子受体拮抗剂和其使用方法 |
| US6613905B1 (en) * | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| JP2002506863A (ja) * | 1998-03-17 | 2002-03-05 | ノボ ノルディスク アクティーゼルスカブ | 新規ヘテロ環式化合物 |
| US6214816B1 (en) | 1998-03-17 | 2001-04-10 | Novo Nordisk A/S | Heterocyclic compounds |
| US6503926B2 (en) | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) * | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7355042B2 (en) * | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) * | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
| CA2523426C (en) | 2003-04-24 | 2013-02-26 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| WO2004112705A2 (en) * | 2003-06-16 | 2004-12-29 | Hypnion, Inc. | Methods for treating sleep disorders |
| NZ573129A (en) | 2006-06-28 | 2011-06-30 | Amgen Inc | Piperazine acetic acid glycine transporter-1 inhibitors |
| AU2017311691B2 (en) * | 2016-08-18 | 2021-12-02 | Vidac Pharma Ltd. | Piperazine derivatives, pharmaceutical compositions and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE562299A (cs) * | 1956-11-15 | |||
| FR1296519A (fr) * | 1959-05-05 | 1962-06-22 | Abbott Lab | Procédé pour la préparation de phénothiazines substituées sur l'azote, de préférence par un groupe pyrrolidinoalkyle substitué |
| DE1159954B (de) * | 1961-11-25 | 1963-12-27 | Boehringer & Soehne Gmbh | Verfahren zur Herstellung neuer 10-(Alkoxypiperidinopropyl)-phenthiazine und ihrer Salze |
| CH454871A (de) * | 1964-01-24 | 1968-04-30 | Geigy Ag J R | Verfahren zur Herstellung von neuen Salzen der Embonsäure |
| GB1517385A (en) * | 1975-08-29 | 1978-07-12 | Eisai Co Ltd | Phenothiazine derivatives |
| MY113463A (en) * | 1994-01-04 | 2002-03-30 | Novo Nordisk As | Novel heterocyclic compounds |
-
1996
- 1996-01-04 UA UA97104938A patent/UA54385C2/uk unknown
- 1996-03-28 US US08/623,289 patent/US5874428A/en not_active Expired - Fee Related
- 1996-04-01 DK DK96907327T patent/DK0820451T3/da active
- 1996-04-01 EP EP96907327A patent/EP0820451B1/en not_active Expired - Lifetime
- 1996-04-01 CZ CZ19973164A patent/CZ291294B6/cs not_active IP Right Cessation
- 1996-04-01 MX MX9707531A patent/MX9707531A/es unknown
- 1996-04-01 CA CA002217197A patent/CA2217197A1/en not_active Abandoned
- 1996-04-01 PL PL96322722A patent/PL187171B1/pl not_active IP Right Cessation
- 1996-04-01 RU RU97118474/04A patent/RU2244713C2/ru not_active IP Right Cessation
- 1996-04-01 DE DE69625806T patent/DE69625806T2/de not_active Expired - Fee Related
- 1996-04-01 KR KR1019970707083A patent/KR100466915B1/ko not_active Expired - Fee Related
- 1996-04-01 ES ES96907327T patent/ES2191090T3/es not_active Expired - Lifetime
- 1996-04-01 WO PCT/DK1996/000139 patent/WO1996031498A1/en not_active Ceased
- 1996-04-01 AT AT96907327T patent/ATE231144T1/de not_active IP Right Cessation
- 1996-04-01 CN CNB961937793A patent/CN1152030C/zh not_active Expired - Fee Related
- 1996-04-01 JP JP8529868A patent/JPH11503127A/ja not_active Ceased
- 1996-04-01 AU AU51003/96A patent/AU708010B2/en not_active Ceased
- 1996-04-01 HU HU9800719A patent/HUP9800719A3/hu unknown
- 1996-04-03 AR ARP960102088A patent/AR007759A1/es unknown
- 1996-04-03 IL IL11781096A patent/IL117810A/en not_active IP Right Cessation
- 1996-05-14 TW TW085104810A patent/TW419463B/zh not_active IP Right Cessation
-
1997
- 1997-10-06 NO NO974605A patent/NO974605L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL117810A (en) | 2001-09-13 |
| UA54385C2 (uk) | 2003-03-17 |
| EP0820451B1 (en) | 2003-01-15 |
| PL187171B1 (pl) | 2004-05-31 |
| HUP9800719A3 (en) | 1999-09-28 |
| HUP9800719A2 (hu) | 1999-06-28 |
| AU5100396A (en) | 1996-10-23 |
| CN1152030C (zh) | 2004-06-02 |
| PL322722A1 (en) | 1998-02-16 |
| CZ291294B6 (cs) | 2003-01-15 |
| KR100466915B1 (ko) | 2005-04-14 |
| DE69625806D1 (de) | 2003-02-20 |
| NO974605D0 (no) | 1997-10-06 |
| CA2217197A1 (en) | 1996-10-10 |
| KR19980703684A (ko) | 1998-12-05 |
| AR007759A1 (es) | 1999-11-24 |
| ES2191090T3 (es) | 2003-09-01 |
| MX9707531A (es) | 1997-11-29 |
| US5874428A (en) | 1999-02-23 |
| NO974605L (no) | 1997-12-04 |
| RU2244713C2 (ru) | 2005-01-20 |
| IL117810A0 (en) | 1996-08-04 |
| DE69625806T2 (de) | 2004-01-22 |
| EP0820451A1 (en) | 1998-01-28 |
| TW419463B (en) | 2001-01-21 |
| AU708010B2 (en) | 1999-07-29 |
| CZ316497A3 (cs) | 1998-03-18 |
| ATE231144T1 (de) | 2003-02-15 |
| JPH11503127A (ja) | 1999-03-23 |
| CN1183781A (zh) | 1998-06-03 |
| WO1996031498A1 (en) | 1996-10-10 |
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