DK0802900T3 - Antiarytmiske (S)-enantiomerer af methansulfonamider - Google Patents
Antiarytmiske (S)-enantiomerer af methansulfonamiderInfo
- Publication number
- DK0802900T3 DK0802900T3 DK95943727T DK95943727T DK0802900T3 DK 0802900 T3 DK0802900 T3 DK 0802900T3 DK 95943727 T DK95943727 T DK 95943727T DK 95943727 T DK95943727 T DK 95943727T DK 0802900 T3 DK0802900 T3 DK 0802900T3
- Authority
- DK
- Denmark
- Prior art keywords
- methanesulfonamides
- compounds
- formula
- antiarrhythmic
- enantiomers
- Prior art date
Links
- 239000003416 antiarrhythmic agent Substances 0.000 title abstract 2
- HNQIVZYLYMDVSB-UHFFFAOYSA-N methanesulfonimidic acid Chemical class CS(N)(=O)=O HNQIVZYLYMDVSB-UHFFFAOYSA-N 0.000 title abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- 230000003288 anthiarrhythmic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000014321 polymorphic ventricular tachycardia Diseases 0.000 abstract 2
- 206010047302 ventricular tachycardia Diseases 0.000 abstract 2
- 125000006545 (C1-C9) alkyl group Chemical group 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37153395A | 1995-01-10 | 1995-01-10 | |
| PCT/US1995/016017 WO1996021643A1 (en) | 1995-01-10 | 1995-12-21 | Antiarrhythmic (s)-enantiomers of methanesulfonamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0802900T3 true DK0802900T3 (da) | 2000-06-13 |
Family
ID=23464353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95943727T DK0802900T3 (da) | 1995-01-10 | 1995-12-21 | Antiarytmiske (S)-enantiomerer af methansulfonamider |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0802900B1 (de) |
| JP (1) | JP3846899B2 (de) |
| CN (1) | CN1057758C (de) |
| AT (1) | ATE189809T1 (de) |
| AU (1) | AU691075B2 (de) |
| CA (1) | CA2207545C (de) |
| DE (1) | DE69515133T2 (de) |
| DK (1) | DK0802900T3 (de) |
| ES (1) | ES2143671T3 (de) |
| GR (1) | GR3033396T3 (de) |
| NO (1) | NO308735B1 (de) |
| NZ (1) | NZ300400A (de) |
| PT (1) | PT802900E (de) |
| WO (1) | WO1996021643A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101412687B (zh) * | 2008-11-10 | 2012-01-11 | 浙江师范大学 | 旋光纯富马酸伊布利特的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1237079A (en) * | 1983-05-23 | 1988-05-24 | Arthur Simon | Antiarrhythmic class iii process |
| ATE111447T1 (de) * | 1989-07-25 | 1994-09-15 | Upjohn Co | Tertiäramin-alkenylphenylalkansulfonamide mit antiarrhythmischer wirkung. |
| CA2103932A1 (en) * | 1992-11-05 | 1994-05-06 | Ramesh N. Patel | Stereoselective reduction of ketones |
-
1995
- 1995-12-21 JP JP52165896A patent/JP3846899B2/ja not_active Expired - Fee Related
- 1995-12-21 ES ES95943727T patent/ES2143671T3/es not_active Expired - Lifetime
- 1995-12-21 DE DE69515133T patent/DE69515133T2/de not_active Expired - Fee Related
- 1995-12-21 DK DK95943727T patent/DK0802900T3/da active
- 1995-12-21 CA CA002207545A patent/CA2207545C/en not_active Expired - Fee Related
- 1995-12-21 WO PCT/US1995/016017 patent/WO1996021643A1/en not_active Ceased
- 1995-12-21 NZ NZ300400A patent/NZ300400A/xx unknown
- 1995-12-21 EP EP95943727A patent/EP0802900B1/de not_active Expired - Lifetime
- 1995-12-21 PT PT95943727T patent/PT802900E/pt unknown
- 1995-12-21 CN CN95197287A patent/CN1057758C/zh not_active Expired - Fee Related
- 1995-12-21 AT AT95943727T patent/ATE189809T1/de not_active IP Right Cessation
- 1995-12-21 AU AU45130/96A patent/AU691075B2/en not_active Ceased
-
1997
- 1997-07-09 NO NO973181A patent/NO308735B1/no not_active IP Right Cessation
-
2000
- 2000-05-11 GR GR20000401084T patent/GR3033396T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3846899B2 (ja) | 2006-11-15 |
| CN1057758C (zh) | 2000-10-25 |
| EP0802900B1 (de) | 2000-02-16 |
| HK1008896A1 (en) | 1999-07-23 |
| NZ300400A (en) | 1998-10-28 |
| DE69515133T2 (de) | 2000-07-13 |
| WO1996021643A1 (en) | 1996-07-18 |
| PT802900E (pt) | 2000-07-31 |
| AU4513096A (en) | 1996-07-31 |
| NO973181L (no) | 1997-07-09 |
| DE69515133D1 (de) | 2000-03-23 |
| EP0802900A1 (de) | 1997-10-29 |
| ATE189809T1 (de) | 2000-03-15 |
| ES2143671T3 (es) | 2000-05-16 |
| JPH11500418A (ja) | 1999-01-12 |
| CA2207545A1 (en) | 1996-07-18 |
| CA2207545C (en) | 2008-02-26 |
| CN1172475A (zh) | 1998-02-04 |
| NO973181D0 (no) | 1997-07-09 |
| NO308735B1 (no) | 2000-10-23 |
| GR3033396T3 (en) | 2000-09-29 |
| AU691075B2 (en) | 1998-05-07 |
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