DK0802181T3 - Hidtil ukendte retinoider - Google Patents

Hidtil ukendte retinoider

Info

Publication number
DK0802181T3
DK0802181T3 DK97105715T DK97105715T DK0802181T3 DK 0802181 T3 DK0802181 T3 DK 0802181T3 DK 97105715 T DK97105715 T DK 97105715T DK 97105715 T DK97105715 T DK 97105715T DK 0802181 T3 DK0802181 T3 DK 0802181T3
Authority
DK
Denmark
Prior art keywords
retinoids
hitherto unknown
hitherto
unknown
unknown retinoids
Prior art date
Application number
DK97105715T
Other languages
Danish (da)
English (en)
Inventor
Michael Klaus
Peter Mohr
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0802181T3 publication Critical patent/DK0802181T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/62Unsaturated compounds containing ether groups, groups, groups, or groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK97105715T 1996-04-15 1997-04-07 Hidtil ukendte retinoider DK0802181T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96105849 1996-04-15

Publications (1)

Publication Number Publication Date
DK0802181T3 true DK0802181T3 (da) 2000-04-17

Family

ID=8222666

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97105715T DK0802181T3 (da) 1996-04-15 1997-04-07 Hidtil ukendte retinoider

Country Status (29)

Country Link
US (1) US5990329A (hu)
JP (1) JP2801589B2 (hu)
KR (1) KR100240542B1 (hu)
CN (1) CN1116270C (hu)
AR (1) AR006632A1 (hu)
AT (1) ATE187962T1 (hu)
AU (1) AU715816B2 (hu)
BR (1) BR9701790A (hu)
CA (1) CA2202228C (hu)
CO (1) CO4890844A1 (hu)
CZ (1) CZ113397A3 (hu)
DE (1) DE59700872D1 (hu)
DK (1) DK0802181T3 (hu)
ES (1) ES2141556T3 (hu)
HK (1) HK1003054A1 (hu)
HR (1) HRP970204B1 (hu)
HU (1) HU220112B (hu)
IL (1) IL120637A (hu)
MA (1) MA24142A1 (hu)
NO (1) NO308842B1 (hu)
NZ (1) NZ314525A (hu)
PE (1) PE42498A1 (hu)
PL (1) PL319477A1 (hu)
PT (1) PT802181E (hu)
SG (1) SG52949A1 (hu)
TR (1) TR199700297A2 (hu)
TW (1) TW442459B (hu)
YU (1) YU14997A (hu)
ZA (1) ZA972944B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2344653A1 (en) 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
WO2003062404A1 (en) 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
EP1799812A4 (en) 2004-09-16 2009-09-09 Gamida Cell Ltd EX VIVO CULTIVATION METHODS OF STEM CELLS AND PRECURSOR BY CO-CULTURE WITH MESENCHYMAL CELLS
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
BR112014020119A2 (pt) 2012-02-13 2020-10-27 Gamida-Cell Ltd cultura de células-tronco mesenquimais
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169103A (en) * 1978-04-12 1979-09-25 Hoffmann-La Roche Inc. Nonatetraenoic acid derivatives
DE2843901A1 (de) * 1978-10-07 1980-04-24 Basf Ag Mittel, enthaltend all-e- oder 13-z-7, 8-dehydro-retinsaeure
CH658387A5 (de) * 1984-04-02 1986-11-14 Hoffmann La Roche Pharmazeutische praeparate.
CZ282548B6 (cs) * 1992-01-22 1997-08-13 F. Hoffmann-La Roche Ag Farmaceutický přípravek

Also Published As

Publication number Publication date
HK1003054A1 (en) 1998-10-09
AU715816B2 (en) 2000-02-10
US5990329A (en) 1999-11-23
CN1116270C (zh) 2003-07-30
YU14997A (sh) 1999-09-27
HU9700747D0 (en) 1997-05-28
CZ113397A3 (cs) 1998-02-18
PE42498A1 (es) 1998-08-18
HU220112B (hu) 2001-11-28
IL120637A (en) 2000-11-21
HUP9700747A1 (en) 1997-12-29
DE59700872D1 (de) 2000-01-27
NO308842B1 (no) 2000-11-06
TW442459B (en) 2001-06-23
ES2141556T3 (es) 2000-03-16
CA2202228C (en) 2007-03-06
JP2801589B2 (ja) 1998-09-21
CO4890844A1 (es) 2000-02-28
CA2202228A1 (en) 1997-10-15
NO971711D0 (no) 1997-04-14
SG52949A1 (en) 1998-09-28
HRP970204A2 (en) 1998-04-30
MA24142A1 (fr) 1997-12-31
NZ314525A (en) 1998-02-26
TR199700297A2 (xx) 1997-11-21
KR100240542B1 (ko) 2000-01-15
NO971711L (no) 1997-10-16
ZA972944B (en) 1997-10-15
AR006632A1 (es) 1999-09-08
AU1772697A (en) 1997-10-23
PT802181E (pt) 2000-05-31
HRP970204B1 (en) 2000-10-31
PL319477A1 (en) 1997-10-27
IL120637A0 (en) 1997-08-14
KR970069969A (ko) 1997-11-07
ATE187962T1 (de) 2000-01-15
MX9702697A (es) 1997-10-31
CN1167752A (zh) 1997-12-17
JPH1036343A (ja) 1998-02-10
BR9701790A (pt) 1998-11-10
HUP9700747A3 (en) 1998-04-28

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