HRP970204B1 - New retinoids - Google Patents

New retinoids

Info

Publication number
HRP970204B1
HRP970204B1 HR970204A HRP970204A HRP970204B1 HR P970204 B1 HRP970204 B1 HR P970204B1 HR 970204 A HR970204 A HR 970204A HR P970204 A HRP970204 A HR P970204A HR P970204 B1 HRP970204 B1 HR P970204B1
Authority
HR
Croatia
Prior art keywords
new retinoids
retinoids
new
Prior art date
Application number
HR970204A
Other languages
English (en)
Inventor
Klaus Michael
Peter Mohr
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HRP970204A2 publication Critical patent/HRP970204A2/xx
Publication of HRP970204B1 publication Critical patent/HRP970204B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/62—Unsaturated compounds containing ether groups, groups, groups, or groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR970204A 1996-04-15 1997-04-14 New retinoids HRP970204B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96105849 1996-04-15

Publications (2)

Publication Number Publication Date
HRP970204A2 HRP970204A2 (en) 1998-04-30
HRP970204B1 true HRP970204B1 (en) 2000-10-31

Family

ID=8222666

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970204A HRP970204B1 (en) 1996-04-15 1997-04-14 New retinoids

Country Status (29)

Country Link
US (1) US5990329A (hu)
JP (1) JP2801589B2 (hu)
KR (1) KR100240542B1 (hu)
CN (1) CN1116270C (hu)
AR (1) AR006632A1 (hu)
AT (1) ATE187962T1 (hu)
AU (1) AU715816B2 (hu)
BR (1) BR9701790A (hu)
CA (1) CA2202228C (hu)
CO (1) CO4890844A1 (hu)
CZ (1) CZ113397A3 (hu)
DE (1) DE59700872D1 (hu)
DK (1) DK0802181T3 (hu)
ES (1) ES2141556T3 (hu)
HK (1) HK1003054A1 (hu)
HR (1) HRP970204B1 (hu)
HU (1) HU220112B (hu)
IL (1) IL120637A (hu)
MA (1) MA24142A1 (hu)
NO (1) NO308842B1 (hu)
NZ (1) NZ314525A (hu)
PE (1) PE42498A1 (hu)
PL (1) PL319477A1 (hu)
PT (1) PT802181E (hu)
SG (1) SG52949A1 (hu)
TR (1) TR199700297A2 (hu)
TW (1) TW442459B (hu)
YU (1) YU14997A (hu)
ZA (1) ZA972944B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2344653A1 (en) 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
WO2003062404A1 (en) 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
EP1799812A4 (en) 2004-09-16 2009-09-09 Gamida Cell Ltd EX VIVO CULTIVATION METHODS OF STEM CELLS AND PRECURSOR BY CO-CULTURE WITH MESENCHYMAL CELLS
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
BR112014020119A2 (pt) 2012-02-13 2020-10-27 Gamida-Cell Ltd cultura de células-tronco mesenquimais
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169103A (en) * 1978-04-12 1979-09-25 Hoffmann-La Roche Inc. Nonatetraenoic acid derivatives
DE2843901A1 (de) * 1978-10-07 1980-04-24 Basf Ag Mittel, enthaltend all-e- oder 13-z-7, 8-dehydro-retinsaeure
CH658387A5 (de) * 1984-04-02 1986-11-14 Hoffmann La Roche Pharmazeutische praeparate.
CZ282548B6 (cs) * 1992-01-22 1997-08-13 F. Hoffmann-La Roche Ag Farmaceutický přípravek

Also Published As

Publication number Publication date
HK1003054A1 (en) 1998-10-09
AU715816B2 (en) 2000-02-10
US5990329A (en) 1999-11-23
CN1116270C (zh) 2003-07-30
DK0802181T3 (da) 2000-04-17
YU14997A (sh) 1999-09-27
HU9700747D0 (en) 1997-05-28
CZ113397A3 (cs) 1998-02-18
PE42498A1 (es) 1998-08-18
HU220112B (hu) 2001-11-28
IL120637A (en) 2000-11-21
HUP9700747A1 (en) 1997-12-29
DE59700872D1 (de) 2000-01-27
NO308842B1 (no) 2000-11-06
TW442459B (en) 2001-06-23
ES2141556T3 (es) 2000-03-16
CA2202228C (en) 2007-03-06
JP2801589B2 (ja) 1998-09-21
CO4890844A1 (es) 2000-02-28
CA2202228A1 (en) 1997-10-15
NO971711D0 (no) 1997-04-14
SG52949A1 (en) 1998-09-28
HRP970204A2 (en) 1998-04-30
MA24142A1 (fr) 1997-12-31
NZ314525A (en) 1998-02-26
TR199700297A2 (xx) 1997-11-21
KR100240542B1 (ko) 2000-01-15
NO971711L (no) 1997-10-16
ZA972944B (en) 1997-10-15
AR006632A1 (es) 1999-09-08
AU1772697A (en) 1997-10-23
PT802181E (pt) 2000-05-31
PL319477A1 (en) 1997-10-27
IL120637A0 (en) 1997-08-14
KR970069969A (ko) 1997-11-07
ATE187962T1 (de) 2000-01-15
MX9702697A (es) 1997-10-31
CN1167752A (zh) 1997-12-17
JPH1036343A (ja) 1998-02-10
BR9701790A (pt) 1998-11-10
HUP9700747A3 (en) 1998-04-28

Similar Documents

Publication Publication Date Title
DE69634986D1 (en) Modulares wandlersystem
DE69608577D1 (en) Thermostabiler schalldämmstoff
DE69702926D1 (en) Polyurethanhartschäume
HU9700328D0 (en) New heteroaryl-oxazolidinones
DE69705420D1 (en) Polyurethanhartschäume
DE69708059D1 (en) Thiophenopyrimidine
DE59705192D1 (en) Lcp-blends
DE59711450D1 (en) Arylalkanoylpyridazine
DE69703480D1 (en) Anionische photokatalysator
DE59700372D1 (en) Blockcopolymere
DE69621466D1 (en) Thermoplastische hydroxy-phenoxyetherpolymerverbundwerkstoffe
DE69710573D1 (en) Morpholinyl-anthracyclinderivate
DE59707730D1 (en) Peripheralpumpe
DE59703905D1 (en) Linearmotorgetriebene transportanlage
HRP970204B1 (en) New retinoids
DE59703023D1 (en) Cyclopeptidderivate
DE59702027D1 (en) Bragg-modulator
DE59711583D1 (en) Heterocyclyluracile
DE59709914D1 (en) Substituierte aromatische phosphonsäurederivate
DE59705556D1 (en) Peripheralpumpe
AU131132S (en) Handleset
DE69706982D1 (en) Wärmeisolationspaneel
GR3032989T3 (en) Retinoids
AU131198S (en) Handleset
DE59610178D1 (en) Rotationspumpe

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20010414

Year of fee payment: 5

PBON Lapse due to non-payment of renewal fee

Effective date: 20020415