DK0785198T3 - Fremgangsmåde til fremstilling af optisk aktiv 3-quinuclidinol - Google Patents

Fremgangsmåde til fremstilling af optisk aktiv 3-quinuclidinol

Info

Publication number
DK0785198T3
DK0785198T3 DK96120280T DK96120280T DK0785198T3 DK 0785198 T3 DK0785198 T3 DK 0785198T3 DK 96120280 T DK96120280 T DK 96120280T DK 96120280 T DK96120280 T DK 96120280T DK 0785198 T3 DK0785198 T3 DK 0785198T3
Authority
DK
Denmark
Prior art keywords
optically active
quinuclidinol
preparation
catalyst
formula
Prior art date
Application number
DK96120280T
Other languages
English (en)
Inventor
Walter Dr Brieden
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK0785198T3 publication Critical patent/DK0785198T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK96120280T 1996-01-19 1996-12-17 Fremgangsmåde til fremstilling af optisk aktiv 3-quinuclidinol DK0785198T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH13996 1996-01-19

Publications (1)

Publication Number Publication Date
DK0785198T3 true DK0785198T3 (da) 2000-11-13

Family

ID=4180140

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96120280T DK0785198T3 (da) 1996-01-19 1996-12-17 Fremgangsmåde til fremstilling af optisk aktiv 3-quinuclidinol

Country Status (9)

Country Link
US (1) US5744606A (da)
EP (1) EP0785198B1 (da)
JP (1) JP4122536B2 (da)
AT (1) ATE194342T1 (da)
CA (1) CA2194727C (da)
DE (1) DE59605542D1 (da)
DK (1) DK0785198T3 (da)
ES (1) ES2147889T3 (da)
PT (1) PT785198E (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK390692A3 (en) * 1991-05-31 1998-02-04 Pfizer Quinuclidine derivatives, preparation method thereof and use
US6921765B2 (en) * 2000-09-20 2005-07-26 Aprea Ab 1-Azabicyclo[2.2.2]octan-3-one derivatives and maleimide derivatives and their use for treating cancer tumors
JP2003230398A (ja) * 2001-12-07 2003-08-19 Daicel Chem Ind Ltd 光学活性アルコールの製造方法
JP2003176266A (ja) * 2001-12-13 2003-06-24 Sumitomo Chem Co Ltd 光学活性なアゼチジンアミド配位遷移金属錯体および用途
DE602004011193D1 (de) * 2003-03-07 2008-02-21 Kawaken Fine Chemicals Co Verfahren zur herstellung von optisch aktivem alkohol in gegenwart von rhodium, einem chiralen ferrocenyldiphosphin und einem optisch aktivem diamin
JP4490211B2 (ja) * 2004-08-27 2010-06-23 高砂香料工業株式会社 光学活性３−キヌクリジノール類の製造方法
WO2006103756A1 (ja) * 2005-03-30 2006-10-05 Kanto Kagaku Kabushiki Kaisha 光学活性キヌクリジノール類の製造方法
JP5172124B2 (ja) 2006-09-29 2013-03-27 関東化学株式会社 ２位に置換基を有する光学活性キヌクリジノール類の製造方法
CN112707899B (zh) * 2019-10-24 2023-10-17 东莞市东阳光动物保健药品有限公司 一种奎宁醇的制备方法
CN111454258B (zh) * 2020-05-28 2021-07-20 中山奕安泰医药科技有限公司 索非那新中间体的制备方法
CN114437060B (zh) * 2020-11-03 2023-04-14 凯特立斯（深圳）科技有限公司 一种(r)-和(s)-3-奎宁环醇的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8817121U1 (de) 1988-11-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Quinuclidine
GB9119705D0 (en) 1991-09-14 1991-10-30 Pfizer Ltd Therapeutic compounds
EP0564406B1 (de) 1992-04-02 1999-05-06 Novartis AG Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
US5215918A (en) * 1992-06-19 1993-06-01 Bend Research, Inc. Enantiomeric enrichment of (R,S)-3-quinuclidinol
IL106142A (en) * 1992-06-29 1997-03-18 Merck & Co Inc Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them
US5536858A (en) * 1994-02-12 1996-07-16 Hoffmann-La Roche Inc. Tetrasulfonated diphosphine compounds and metal complexes thereof for asymmetric catalytic reactions

Also Published As

Publication number Publication date
US5744606A (en) 1998-04-28
DE59605542D1 (de) 2000-08-10
EP0785198A1 (de) 1997-07-23
CA2194727C (en) 2005-04-12
JPH09194480A (ja) 1997-07-29
PT785198E (pt) 2000-11-30
JP4122536B2 (ja) 2008-07-23
CA2194727A1 (en) 1997-07-20
ES2147889T3 (es) 2000-10-01
EP0785198B1 (de) 2000-07-05
ATE194342T1 (de) 2000-07-15

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