ATE114629T1 - Verfahren zur carbonylierung von arylalkylhalogeniden. - Google Patents
Verfahren zur carbonylierung von arylalkylhalogeniden.Info
- Publication number
- ATE114629T1 ATE114629T1 AT89303995T AT89303995T ATE114629T1 AT E114629 T1 ATE114629 T1 AT E114629T1 AT 89303995 T AT89303995 T AT 89303995T AT 89303995 T AT89303995 T AT 89303995T AT E114629 T1 ATE114629 T1 AT E114629T1
- Authority
- AT
- Austria
- Prior art keywords
- carbonylation
- halogens
- arylalkyl
- processes
- ibuprofen
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000006315 carbonylation Effects 0.000 title 1
- 238000005810 carbonylation reaction Methods 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 title 1
- 150000002367 halogens Chemical class 0.000 title 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 4
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 229960001680 ibuprofen Drugs 0.000 abstract 2
- 229910052763 palladium Inorganic materials 0.000 abstract 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 1
- -1 ethyl halide Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18518488A | 1988-04-22 | 1988-04-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE114629T1 true ATE114629T1 (de) | 1994-12-15 |
Family
ID=22679948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89303995T ATE114629T1 (de) | 1988-04-22 | 1989-04-21 | Verfahren zur carbonylierung von arylalkylhalogeniden. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6555704B1 (de) |
| EP (1) | EP0338852B1 (de) |
| JP (1) | JP2717698B2 (de) |
| KR (1) | KR0161238B1 (de) |
| AT (1) | ATE114629T1 (de) |
| CA (1) | CA1338592C (de) |
| DE (1) | DE68919514T2 (de) |
| ES (1) | ES2065373T3 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4990658B1 (en) * | 1989-12-18 | 1994-08-30 | Ethyl Corp | Process for preparing ibuprofen and its alkyl esters |
| US6268526B1 (en) * | 1998-12-16 | 2001-07-31 | Albemarle Corporation | Palladium catalyzed carbonylation process utilizing aromatic substituted alcohols and/or aromatic substituted alkyl halides |
| US6660883B1 (en) * | 2000-09-14 | 2003-12-09 | Council Of Scientific And Industrial Research | Process for the preparation of 2-aryl propionic acids |
| DE10057262A1 (de) * | 2000-11-18 | 2002-05-23 | Clariant Gmbh | Verfahren zur Herstellung von Phenylessigsäurederivaten |
| WO2006010885A1 (en) * | 2004-07-30 | 2006-02-02 | Heriot-Watt University | Palladacyles, their preparation and catalytic processes involving their use as catalyst, especially catalytic carbonylation processes |
| TWI438034B (zh) | 2010-11-24 | 2014-05-21 | Ind Tech Res Inst | 一種觸媒載體、承載於該觸媒載體之觸媒及使用該觸媒之碳-碳偶合反應方法 |
| CN102140062B (zh) * | 2011-03-13 | 2012-11-14 | 联化科技股份有限公司 | 一种2,5-二甲基苯乙酸的制备方法 |
| CN112955250B (zh) | 2018-09-17 | 2024-06-11 | 巴斯夫欧洲公司 | 在升高的压力下进行化学反应的方法和装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2859253A (en) * | 1955-10-19 | 1958-11-04 | Heyden Newport Chemical Corp | Process for the continuous preparation of benzyl chloride |
| JPS5635659A (en) * | 1979-08-31 | 1981-04-08 | Toshiba Corp | Manufacture of rotor core |
| JPS5995238A (ja) * | 1982-11-19 | 1984-06-01 | Mitsubishi Petrochem Co Ltd | フエニル酢酸誘導体の製造法 |
| JPS5995239A (ja) | 1982-11-22 | 1984-06-01 | Mitsubishi Petrochem Co Ltd | α−(6−メトキシ−2−ナフチル)プロピオン酸の製造法 |
| US4668816A (en) * | 1985-11-12 | 1987-05-26 | Stauffer Chemical Company | High yield carbonylation of halo-hydrocarbons |
| US4981995A (en) | 1987-03-20 | 1991-01-01 | Varadaraj Elango | Method for producing ibuprofen |
-
1989
- 1989-04-14 CA CA000596739A patent/CA1338592C/en not_active Expired - Fee Related
- 1989-04-21 EP EP89303995A patent/EP0338852B1/de not_active Expired - Lifetime
- 1989-04-21 JP JP1100365A patent/JP2717698B2/ja not_active Expired - Lifetime
- 1989-04-21 ES ES89303995T patent/ES2065373T3/es not_active Expired - Lifetime
- 1989-04-21 AT AT89303995T patent/ATE114629T1/de not_active IP Right Cessation
- 1989-04-21 DE DE68919514T patent/DE68919514T2/de not_active Expired - Lifetime
- 1989-04-21 KR KR1019890005281A patent/KR0161238B1/ko not_active Expired - Lifetime
-
1995
- 1995-05-22 US US08/445,593 patent/US6555704B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01311044A (ja) | 1989-12-15 |
| US6555704B1 (en) | 2003-04-29 |
| KR890015990A (ko) | 1989-11-27 |
| EP0338852B1 (de) | 1994-11-30 |
| ES2065373T3 (es) | 1995-02-16 |
| CA1338592C (en) | 1996-09-10 |
| EP0338852A1 (de) | 1989-10-25 |
| DE68919514T2 (de) | 1995-04-13 |
| JP2717698B2 (ja) | 1998-02-18 |
| KR0161238B1 (ko) | 1999-01-15 |
| DE68919514D1 (de) | 1995-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |