DK0782573T3 - Brefeldin og analoger til forbedret synaptisk transmission - Google Patents

Brefeldin og analoger til forbedret synaptisk transmission

Info

Publication number
DK0782573T3
DK0782573T3 DK95930845T DK95930845T DK0782573T3 DK 0782573 T3 DK0782573 T3 DK 0782573T3 DK 95930845 T DK95930845 T DK 95930845T DK 95930845 T DK95930845 T DK 95930845T DK 0782573 T3 DK0782573 T3 DK 0782573T3
Authority
DK
Denmark
Prior art keywords
brefeldin
analogs
synaptic transmission
enhanced synaptic
enhanced
Prior art date
Application number
DK95930845T
Other languages
English (en)
Inventor
Katumi Sumikawa
Ken-Ichi Ito
James L Mcgaugh
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK0782573T3 publication Critical patent/DK0782573T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
DK95930845T 1994-09-20 1995-08-16 Brefeldin og analoger til forbedret synaptisk transmission DK0782573T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30987194A 1994-09-20 1994-09-20
PCT/US1995/010454 WO1996009299A1 (en) 1994-09-20 1995-08-16 Drugs to improved synaptic transmission

Publications (1)

Publication Number Publication Date
DK0782573T3 true DK0782573T3 (da) 2000-06-05

Family

ID=23200041

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95930845T DK0782573T3 (da) 1994-09-20 1995-08-16 Brefeldin og analoger til forbedret synaptisk transmission

Country Status (11)

Country Link
US (2) US6710073B1 (da)
EP (1) EP0782573B1 (da)
JP (1) JPH10508579A (da)
KR (1) KR970706271A (da)
AT (1) ATE190056T1 (da)
AU (1) AU703667B2 (da)
DE (1) DE69515321T2 (da)
DK (1) DK0782573T3 (da)
ES (1) ES2143068T3 (da)
NO (1) NO315929B1 (da)
WO (1) WO1996009299A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998033498A1 (en) * 1997-02-05 1998-08-06 Allelix Pharm-Eco L.P. Drugs for memory enhancement
GB0117645D0 (en) 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
WO2009019032A2 (en) * 2003-08-08 2009-02-12 Dsm Ip Assets B.V. Novel method for screening brain-active compounds
EP2708147B1 (en) * 2012-09-14 2020-03-11 Abbott Laboratories Methods for increasing brain functionality using 2-fucosyl-lactose
EP2708145B1 (en) 2012-09-14 2016-05-04 Abbott Laboratories Nutritional compositions for use in methods for modulating corticosterone levels in psychologically stressed individuals
CN112851622B (zh) * 2019-11-28 2023-01-10 中国海洋大学 一种大环内酯布雷菲德菌素a酯类衍生物及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5611710B2 (da) * 1972-09-13 1981-03-16
JPS57159710A (en) * 1981-03-28 1982-10-01 Koki Yagishita Antifungal germicide
DE3247379A1 (de) * 1982-12-22 1984-06-28 Basf Ag, 6700 Ludwigshafen Brefeldin-a-derivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
PH22879A (en) * 1986-01-23 1989-01-19 Hoffmann La Roche Benzazecine derivatives
US5214039A (en) * 1990-02-02 1993-05-25 Taiho Pharmaceutical Co., Limited Bicyclolactam derivative for improving cerebral function
US5242932A (en) 1991-12-17 1993-09-07 The Rockefeller University Treatment of amyloidosis associated with alzheimer disease
DE4305249A1 (de) * 1993-02-20 1994-08-25 Hoechst Ag Galaktosylbrefeldin A, ein neuer Metabolit mit pharmakologischer Wirkung, ein Verfahren zu seiner Herstellung und seine Verwendung

Also Published As

Publication number Publication date
NO315929B1 (no) 2003-11-17
US7081474B2 (en) 2006-07-25
KR970706271A (ko) 1997-11-03
WO1996009299A1 (en) 1996-03-28
US20040242553A1 (en) 2004-12-02
US6710073B1 (en) 2004-03-23
NO971274L (no) 1997-03-19
ES2143068T3 (es) 2000-05-01
AU703667B2 (en) 1999-04-01
EP0782573A1 (en) 1997-07-09
JPH10508579A (ja) 1998-08-25
ATE190056T1 (de) 2000-03-15
EP0782573B1 (en) 2000-03-01
EP0782573A4 (en) 1998-01-14
DE69515321T2 (de) 2000-08-24
NO971274D0 (no) 1997-03-19
DE69515321D1 (de) 2000-04-06
AU3407695A (en) 1996-04-09

Similar Documents

Publication Publication Date Title
MX9203236A (es) Composicion farmaceutica que comprende una ciclosporina.
IS3927A (is) Kviðsjáráhald til að koma fyrir innvortis fyrirbandi
NO983266L (no) Distribuert Behandling
NO20004743D0 (no) Farmasøytiske blandinger inneholdende irbesartan og et diuretium
DK0508658T4 (da) Aseptisk ventilkonstruktion
DE69415126D1 (de) Gegenflusspipelineprozessor
DK0782573T3 (da) Brefeldin og analoger til forbedret synaptisk transmission
FR2515405B1 (fr) Registre a decalage dynamique rapide utilisant des transistors mes
DE69209818D1 (de) Ueberdruckventil
ES1038163Y (es) Dispositivo en un barco.
ES2093779T3 (es) Formulacion farmaceutica que contiene diritromicina.
MX9202187A (es) Montaje de aeracion para introducir gas en una tuberia que contiene solidos.
IT230189Y1 (it) Dispositivo per mantenere fresca una bottiglia.
ES2105930B1 (es) Puya de picador perfeccionada.
IT1230889B (it) Procedimento per realizzare, per coestrusione, un tubo alleggerito e filiera per la sua realizzazione.
KR930013396U (ko) 파이프렌치(pipe wrench)
KR930013392U (ko) 파이프 렌치(Pipe wrench)
ES1030301Y (es) Muñeco perfeccionado que simula beber.
ES1031633Y (es) Dispositivo para producir efectos especiales en carteles.
KR930010702U (ko) 학습용 노트
BR7101314U (pt) Totem publicitario
KR950001538U (ko) 수압을 이용한 조명장치
KR950012366U (ko) 한글 출력장치
SE9003147D0 (sv) Anordning som tillaater vaetska/gas att passera i enbart en riktning
BR9103744A (pt) Bancada simples e dupla face