DK0776376T3 - Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces - Google Patents

Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces

Info

Publication number
DK0776376T3
DK0776376T3 DK95929679T DK95929679T DK0776376T3 DK 0776376 T3 DK0776376 T3 DK 0776376T3 DK 95929679 T DK95929679 T DK 95929679T DK 95929679 T DK95929679 T DK 95929679T DK 0776376 T3 DK0776376 T3 DK 0776376T3
Authority
DK
Denmark
Prior art keywords
template
rna
nucleic acid
dna
reagents
Prior art date
Application number
DK95929679T
Other languages
Danish (da)
English (en)
Inventor
Roy Sooknanan
Original Assignee
Organon Teknika Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Teknika Bv filed Critical Organon Teknika Bv
Application granted granted Critical
Publication of DK0776376T3 publication Critical patent/DK0776376T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK95929679T 1994-07-15 1995-07-13 Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces DK0776376T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27525094A 1994-07-15 1994-07-15
PCT/CA1995/000423 WO1996002668A1 (fr) 1994-07-15 1995-07-13 Utilisation d'arn polymerase pour ameliorer un procede d'amplification d'acide nucleique

Publications (1)

Publication Number Publication Date
DK0776376T3 true DK0776376T3 (da) 2002-02-18

Family

ID=23051486

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95929679T DK0776376T3 (da) 1994-07-15 1995-07-13 Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces

Country Status (12)

Country Link
US (1) US6025134A (fr)
EP (1) EP0776376B1 (fr)
JP (1) JP3881009B2 (fr)
KR (1) KR100392551B1 (fr)
AT (1) ATE209258T1 (fr)
AU (1) AU711115B2 (fr)
CA (1) CA2195209C (fr)
DE (1) DE69524105T2 (fr)
DK (1) DK0776376T3 (fr)
ES (1) ES2168380T3 (fr)
PT (1) PT776376E (fr)
WO (1) WO1996002668A1 (fr)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712127A (en) * 1996-04-29 1998-01-27 Genescape Inc. Subtractive amplification
AU4938497A (en) 1996-11-12 1998-06-03 Visible Genetics Inc. Method and kit for direct isothermal sequencing of nucleic acids
ZA989950B (en) * 1997-11-17 1999-05-04 Akzo Nobel Nv Transcription based amplification of double stranded DNA targets
PT1056884E (pt) 1998-02-27 2002-06-28 Pamgene Bv Processo para a amplificacao nao especifica de acido nucleico
WO2000000638A2 (fr) * 1998-06-26 2000-01-06 Akzo Nobel N.V. Marquage d'amplicons d'arn produits au moyen d'une amplification fondee sur la transcription
AU759915B2 (en) * 1998-07-31 2003-05-01 Gen-Probe Incorporated Reversible inhibiting probes
US7122314B2 (en) 2002-01-30 2006-10-17 Id Biomedical Corporation Methods for detecting vancomycin-resistant microorganisms and compositions therefor
JP4377810B2 (ja) 2002-05-17 2009-12-02 アメリカ合衆国 アスペルギルス種の分子的同定方法
US20040018494A1 (en) * 2002-07-25 2004-01-29 Shurtliff Roxanne N Isothermal transcription based amplification assay for detection and quantification of guanylyl cyclase C
EP1545575A4 (fr) 2002-09-19 2006-04-05 Us Gov Health & Human Serv Polypeptides p. ariasi polypeptides p. perniciosus et methodes d'utilisation
US7485306B2 (en) 2002-10-29 2009-02-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Lutzomyia longipalpis polypeptides and methods of use
US7863041B2 (en) 2005-10-14 2011-01-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Rabies virus vector systems and compositions and methods thereof
EP1991700B1 (fr) 2006-02-13 2012-01-11 The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services Amorces et sondes pour la detection et la discrimination de types et de sous-types des virus de la grippe
EP2397852B1 (fr) 2006-03-14 2013-12-04 Oregon Health and Science University Procédés pour détecter une infection de tuberculose à mycobactérie
SI2079760T1 (sl) 2006-12-27 2016-11-30 Emory University Sestavki in metode za zdravljenje okužb
CA2678404C (fr) 2007-02-28 2019-03-19 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polypeptides brachyury et procedes d'utilisation.
WO2009125303A2 (fr) 2008-04-10 2009-10-15 Genenews Corporation Procédé et appareil de détermination d'une probabilité de cancer colorectal chez un sujet
WO2010034007A2 (fr) 2008-09-22 2010-03-25 Oregon Health & Science University Méthodes permettant de détecter une infection par le bacille de koch
WO2010063011A2 (fr) 2008-11-28 2010-06-03 Emory University Procédés pour le traitement d'infections et de tumeurs
US20120004133A1 (en) 2009-02-20 2012-01-05 The Johns Hopkins University Method for the diagnosis of age-associated vascular disorders
AU2010253978B2 (en) 2009-05-29 2014-12-11 Ventana Medical Systems, Inc. Methods of scoring gene copy number in a biological sample using in situ hybridization
WO2010138908A1 (fr) 2009-05-29 2010-12-02 Ventana Medical Systems, Inc. Nombre de copies du gène igf1r en tant que marqueur pronostique dans un cancer du poumon non à petites cellules
US8835117B2 (en) 2009-05-29 2014-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Nucleic acids for detection and discrimination of genotypes of Chlamydophila psittaci
EP2480572B1 (fr) 2009-09-25 2019-01-30 The United States of America, as represented by The Secretary, Department of Health and Human Services Anticorps neutralisants dirigés contre le vih-1 et utilisation associée
US9181306B2 (en) 2009-10-16 2015-11-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Insertion of foreign genes in rubella virus and their stable expression in a live, attenuated viral vaccine
US9173930B2 (en) 2009-11-20 2015-11-03 Oregon Health & Science University Methods for detecting a mycobacterium tuberculosis infection
WO2011133474A2 (fr) 2010-04-18 2011-10-27 Beth Israel Deaconess Medical Center Méthodes de prédiction d'une prédisposition ou d'un risque d'exposition à l'insuffisance rénale
EP2558596B1 (fr) 2010-04-16 2018-03-14 The Government Of The United States Of America As Reresented By The Secretary Of The Department Of Health & Human Services Dosage par pcr en temps réel pour détecter des pathogènes respiratoires bactériens
CN103068851B (zh) 2010-06-16 2015-03-11 高等教育联邦系统-匹兹堡大学 内质蛋白的抗体及其用途
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
DK2611925T3 (en) 2010-08-30 2018-02-26 Dow Agrosciences Llc AMPLIFIER ELEMENTS OF BACCILE-SUGAR PIPE VIRUS (SCBV) AND ITS USE IN FUNCTIONAL RESEARCH IN PLANTS
CA2809644C (fr) 2010-08-30 2020-06-30 Agrigenetics, Inc. Plateforme de marquage d'activation pour mais et population marquee resultante et plantes
CA2825218A1 (fr) 2011-01-25 2012-08-02 Almac Diagnostics Limited Signatures d'expression genique pour le cancer du colon et methodes d'utilisation
US9150644B2 (en) 2011-04-12 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
US8741564B2 (en) 2011-05-04 2014-06-03 Htg Molecular Diagnostics, Inc. Quantitative nuclease protection assay (QNPA) and sequencing (QNPS) improvements
EP2729583B1 (fr) 2011-07-05 2019-05-22 The Govt. Of The U.S.A. As Represented By The Secretary Of The Department Of Health & Human Services Essai de génotypage de vih-1 pour la surveillance globale d'une résistance à un médicament de vih-1
WO2013049535A2 (fr) 2011-09-30 2013-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Vaccin antigrippal
US9890431B2 (en) 2011-11-15 2018-02-13 Université Libre de Bruxelles Streptococcus pneumoniae detection in blood
KR20140130506A (ko) 2012-02-29 2014-11-10 다우 아그로사이언시즈 엘엘씨 사탕수수 바실루스형 바이러스 (scbv) 인핸서 및 식물 기능성 유전체학에서의 이의 용도
WO2013142808A1 (fr) 2012-03-23 2013-09-26 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Isolats de phlebovirus pathogènes, ainsi que des compositions et des méthodes d'utilisation
WO2013148147A1 (fr) 2012-03-26 2013-10-03 The U.S.A., As Represented By The Secretary Dept. Of Health And Human Services Analyse de la méthylation de l'adn à des fins diagnostiques, pronostiques et thérapeutiques des néoplasies des glandes surrénales
WO2013152352A1 (fr) 2012-04-06 2013-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Vecteur de la rubéole atténué, vivant, pour exprimer des antigènes de vaccin
WO2013162828A1 (fr) 2012-04-27 2013-10-31 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Utilisation d'oligonucléotides cpg co-formulés avec un antibiotique pour accélérer la cicatrisation des plaies
WO2013165551A1 (fr) 2012-05-03 2013-11-07 The Government Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services Procédés de détection du virus de la grippe
US9394574B2 (en) 2012-06-12 2016-07-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for detecting Legionella nucleic acids in a sample
US9631243B2 (en) 2012-06-18 2017-04-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for identifying JC virus
WO2014043518A1 (fr) 2012-09-14 2014-03-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Protéine brachyury, vecteurs non levure, non poxvirus, codant pour la protéine brachyury, et leur utilisation
WO2014093702A1 (fr) 2012-12-12 2014-06-19 The Usa, As Represented By The Secretary, Department Of Health And Human Services Agents thérapeutiques du vih et procédés de fabrication et d'utilisation associés
EP3323884A1 (fr) 2013-02-01 2018-05-23 The United States Of America as Represented by the Secretary, Department of Health an Human Service Procédé de génération de cellules de l'épithélium pigmentaire rétinien (epr) à partir de cellules souches pluripotentes induites (ipscs)
EP2956169B1 (fr) 2013-02-12 2018-04-11 THE UNITED STATES OF AMERICA, represented by the S Anticorps monoclonaux neutralisant les norovirus
US10612088B2 (en) 2013-03-14 2020-04-07 The Broad Institute, Inc. Massively multiplexed RNA sequencing
CN105392882A (zh) 2013-04-19 2016-03-09 加利福尼亚大学董事会 孤星病毒
US10000556B2 (en) 2013-05-09 2018-06-19 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Single-domain VHH antibodies directed to norovirus GI.1 and GII.4 and their use
US10006097B2 (en) 2013-10-22 2018-06-26 The United States of America, as represented by the Secretry, Department of Health and Human Services Compositions and methods for detection and discrimination of influenza viruses
US10398772B2 (en) 2014-01-08 2019-09-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ras pathways as markers of protection against HIV and methods to improve vaccine efficacy
EP3107930A1 (fr) 2014-02-21 2016-12-28 THE UNITED STATES OF AMERICA, represented by the S Acides nucléiques du vih-2 et leurs procédés de détection
US20170044631A1 (en) 2014-04-14 2017-02-16 The Unite States of America, as represented by the Secretary, Dept. of Health and Human Services Methods for rapid detection and identification of viral nucleic acids
WO2015199976A1 (fr) 2014-06-24 2015-12-30 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Microdissection activée par une cible
EP3175244A4 (fr) 2014-07-30 2018-06-13 Mor Research Applications Ltd. Compositions pour le traitement de la leucémie lymphoblastique aiguë et procédés de leur utilisation
US10934360B2 (en) 2014-07-31 2021-03-02 The Hong Kong University Of Science And Technology Human monoclonal antibodies against EPHA4 and their use
US11279974B2 (en) 2014-12-01 2022-03-22 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
WO2016090170A1 (fr) 2014-12-05 2016-06-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anticorps puissant anti-neuraminidase d'un sous-type n1 du virus de la grippe a
WO2016134144A1 (fr) 2015-02-20 2016-08-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Méthodes et réactifs pour la détection du virus ebola
WO2016145409A1 (fr) 2015-03-11 2016-09-15 The Broad Institute, Inc. Couplage de génotype et de phénotype
WO2017031370A1 (fr) 2015-08-18 2017-02-23 The Broad Institute, Inc. Procédés et compositions permettant de changer la fonction et la structure de boucles et/ou de domaines de chromatine
WO2017062246A1 (fr) 2015-10-05 2017-04-13 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Souche de rotavirus humain g9p[6] et utilisation comme vaccin
WO2017192589A1 (fr) 2016-05-02 2017-11-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anticorps neutralisants dirigés contre la grippe ha, leur utilisation et leur identification
US11155885B2 (en) 2016-05-20 2021-10-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Real-time reverse transcriptase-polymerase chain reaction assay with modified probe for the diagnosis of rabies viruses and other lyssaviruses
US11248272B2 (en) 2016-06-27 2022-02-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for influenza a virus subtyping
MY200048A (en) 2016-12-06 2023-12-06 Univ Oregon State Compositions and methods for enhanced production of enduracidin in a genetically engineered strain of streptomyces fungicidicus
WO2018204175A1 (fr) 2017-05-03 2018-11-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Détection rapide du virus zika par amplification isotherme médiée par une boucle de transcription inverse
WO2018232028A1 (fr) 2017-06-14 2018-12-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Détection de gènes de résistance antibactérienne blaimp
GB201710838D0 (en) 2017-07-05 2017-08-16 Ucl Business Plc Bispecific antibodies
US11733248B2 (en) 2017-09-25 2023-08-22 Fred Hutchinson Cancer Center High efficiency targeted in situ genome-wide profiling
EP3692152A4 (fr) 2017-10-04 2021-12-01 The Broad Institute, Inc. Procédés et compositions permettant de modifier la fonction et la structure de boucles et/ou de domaines de chromatine
WO2019133727A1 (fr) 2017-12-29 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ensemble de sondes universelles de virus de la grippe pour l'enrichissement d'un quelconque acide nucléique du virus de la grippe
WO2019152860A1 (fr) 2018-02-02 2019-08-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Procédés d'amplification aléatoire de quantités extrêmement faibles d'acides nucléiques en entrée
KR20210061336A (ko) 2018-07-27 2021-05-27 아페르타 바이오사이언시스 엘엘씨 모낭충으로 유발된 안구 및 안면 증상의 치료를 위한 스피노신 제제
US11844800B2 (en) 2019-10-30 2023-12-19 Massachusetts Institute Of Technology Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
WO2022056078A1 (fr) 2020-09-11 2022-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dosage de détection assisté par rnase h d'arn (radar)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340807C (fr) * 1988-02-24 1999-11-02 Lawrence T. Malek Procede d'amplification d'une sequence d'acide nucleique
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
WO1991001384A1 (fr) * 1989-07-11 1991-02-07 Gen-Probe, Incorporated Methodes d'amplification de sequences d'acides nucleiques faisant appel a un complexe de transcription
WO1991004340A1 (fr) * 1989-09-20 1991-04-04 Cambridge Biotech Corporation Amplification isothermique in vitro de l'acide nucleique
ATE146226T1 (de) * 1989-09-21 1996-12-15 Camborne Ind Plc Wiedergewinnung von schrott

Also Published As

Publication number Publication date
ES2168380T3 (es) 2002-06-16
KR100392551B1 (ko) 2003-10-30
AU3336695A (en) 1996-02-16
CA2195209C (fr) 2008-09-23
US6025134A (en) 2000-02-15
WO1996002668A1 (fr) 1996-02-01
AU711115B2 (en) 1999-10-07
EP0776376B1 (fr) 2001-11-21
DE69524105T2 (de) 2002-07-18
CA2195209A1 (fr) 1996-02-01
DE69524105D1 (de) 2002-01-03
JP3881009B2 (ja) 2007-02-14
ATE209258T1 (de) 2001-12-15
JPH11505402A (ja) 1999-05-21
EP0776376A1 (fr) 1997-06-04
PT776376E (pt) 2002-05-31

Similar Documents

Publication Publication Date Title
DK0776376T3 (da) Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces
DK0408295T3 (da) Fremgangsmåder til opformering af nukleinsyresekvenser
Burrell Enzymes of molecular biology
DK0970240T3 (da) Kunstig fejlparringshydridisering
ATE278020T1 (de) Modifizierte thermostabile dna polymerase
CA2076750A1 (fr) Amplification de l'acide nucleique avec activite de l'adn-polymerase arn-dependante des arn replicases
ATE188743T1 (de) Oligonukleotiden komplementär zu mycobakterieller nukleinsäure
DK0487628T3 (da) Forbedret fremgangsmåde til nukleinsyre-amplifikation
CY2406B1 (en) Assaying nucleotides in solution using pna probes.
SE8700821D0 (sv) Quantitative determination of nucleic acid molecules and the reagent kit used
DE69924140D1 (de) Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen
SE9201929D0 (sv) Method and system for molecular-biological diagnostics
DE50115782D1 (de) THERMOSTABILE POLYMERASE AUS i THERMOCOCCUS PACIFICUS /i
ATE359369T1 (de) Rns-abhängige rns-polymerase, die vorzugsweise anhand einer rna-matrix funktioniert und ein promoter-abhängiger transkriptionsprozess , der diese rns-abhängige rns-polymerase benutzt.
ATE408621T1 (de) Dna moleküle
ATE325189T1 (de) Klonierungsverfahren durch multiple verdauung
WO1998049341A3 (fr) Sequençage d'un polynucleotide au moyen d'amorces semidegenerees
Litt et al. Characterization of (CA) n Microsatellite Repeats from Large‐Insert Clones
Valle PCR-based method to map the bending locus of DNA molecules.
Dillon et al. Construction of Synthetic Genes by Polymerase Chain Reaction