DK0744947T3 - Metronidazolpræparater med modificeret afgivelse og fremgangsmåde til deres fremstilling og anvendelse - Google Patents

Metronidazolpræparater med modificeret afgivelse og fremgangsmåde til deres fremstilling og anvendelse

Info

Publication number
DK0744947T3
DK0744947T3 DK95907963T DK95907963T DK0744947T3 DK 0744947 T3 DK0744947 T3 DK 0744947T3 DK 95907963 T DK95907963 T DK 95907963T DK 95907963 T DK95907963 T DK 95907963T DK 0744947 T3 DK0744947 T3 DK 0744947T3
Authority
DK
Denmark
Prior art keywords
metronidazole
aqueous
methods
aqueous soluble
compositions
Prior art date
Application number
DK95907963T
Other languages
English (en)
Inventor
Subhash Desai
Alan Mark Mancini
Steven Charles Schumann
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of DK0744947T3 publication Critical patent/DK0744947T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK95907963T 1994-01-27 1995-01-04 Metronidazolpræparater med modificeret afgivelse og fremgangsmåde til deres fremstilling og anvendelse DK0744947T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/187,568 US6103262A (en) 1994-01-27 1994-01-27 Modified-release metronidazole compositions and methods for making and using same
PCT/US1995/000005 WO1995020383A1 (en) 1994-01-27 1995-01-04 Modified-release metronidazole compositions and methods for making and using same

Publications (1)

Publication Number Publication Date
DK0744947T3 true DK0744947T3 (da) 2002-07-29

Family

ID=22689500

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95907963T DK0744947T3 (da) 1994-01-27 1995-01-04 Metronidazolpræparater med modificeret afgivelse og fremgangsmåde til deres fremstilling og anvendelse

Country Status (16)

Country Link
US (2) US6103262A (da)
EP (1) EP0744947B1 (da)
JP (1) JPH09508381A (da)
KR (1) KR100368769B1 (da)
CN (1) CN1095665C (da)
AT (1) ATE216236T1 (da)
AU (1) AU682248B2 (da)
BR (1) BR9506662A (da)
CA (1) CA2181985C (da)
DE (1) DE69526434T2 (da)
DK (1) DK0744947T3 (da)
ES (1) ES2174930T3 (da)
MX (1) MX9602951A (da)
NZ (1) NZ279368A (da)
PT (1) PT744947E (da)
WO (1) WO1995020383A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8588898A (en) 1997-07-28 1999-02-16 Mary L. Redmond Composition and process for the treatment of epidermal traumas such as decubitusulcers
US20010055613A1 (en) 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
DE19850445A1 (de) * 1998-11-02 2000-05-04 Falk Pharma Gmbh Arzneimittel zur topischen Behandlung entzündlicher Darmerkrankungen
ECSP003851A (es) * 1999-12-22 2002-05-23 Pharmacia Corp Composicon de liberacion doble de un inhibidor ciclooxigenasa-2
US6423707B1 (en) 2000-08-28 2002-07-23 California Pacific Medical Center Nitroimidazole ester analogues and therapeutic applications
US8846100B2 (en) * 2006-05-12 2014-09-30 Shire Llc Controlled dose drug delivery system
WO2012075015A2 (en) 2010-11-29 2012-06-07 Dr. Reddy's Laboratories Ltd. Oral metronidazole pharmaceutical compositions
WO2013111070A1 (en) * 2012-01-23 2013-08-01 Ranbaxy Laboratories Limited In-situ multilayered tablet technology
KR20170052626A (ko) 2014-09-05 2017-05-12 심바이오믹스 세러퓨틱스 엘엘씨 세균질증 치료에 사용하기 위한 세크니다졸
CA2988082C (en) * 2015-06-01 2020-09-29 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
WO2017027528A1 (en) * 2015-08-10 2017-02-16 Purdue Research Foundation Methods and systems for depositing active ingredients on substrates
GR1008992B (el) 2015-12-17 2017-03-23 Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων Φαρμακευτικη συνθεση σε μορφη κοκκιων για χορηγηση απο το στομα που περιεχει μετρονιδαζολη ή παραγωγα αυτης και εναν παραγοντα καλυψης της γευσης
CN112007002B (zh) * 2020-08-05 2022-08-12 河北君临药业有限公司 一种质量稳定的甲硝唑片剂组合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2944061A (en) * 1957-09-20 1960-07-05 Acyl derivatives and process
FI63335B (fi) * 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
JPS6056122B2 (ja) * 1980-05-21 1985-12-09 塩野義製薬株式会社 徐放性製剤
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
US4927639A (en) * 1989-02-02 1990-05-22 Warner-Lambert Company Modified release gemfibrozil composition
DE4125048A1 (de) * 1991-07-29 1993-02-04 Peggy Albrecht Arzneimittel mit verzoegerter freisetzung zur behandlung von periodontitis
CA2093282C (en) * 1992-05-04 1999-01-12 Tibor Sipos Intraoral medicament-releasing device

Also Published As

Publication number Publication date
MX9602951A (es) 1997-06-28
WO1995020383A1 (en) 1995-08-03
CA2181985A1 (en) 1995-08-03
US5618559A (en) 1997-04-08
CN1139382A (zh) 1997-01-01
CA2181985C (en) 2000-12-05
NZ279368A (en) 1998-04-27
JPH09508381A (ja) 1997-08-26
ATE216236T1 (de) 2002-05-15
AU1596795A (en) 1995-08-15
EP0744947A1 (en) 1996-12-04
CN1095665C (zh) 2002-12-11
ES2174930T3 (es) 2002-11-16
PT744947E (pt) 2002-08-30
AU682248B2 (en) 1997-09-25
BR9506662A (pt) 1997-11-18
KR100368769B1 (ko) 2003-05-16
DE69526434D1 (de) 2002-05-23
DE69526434T2 (de) 2002-10-31
EP0744947B1 (en) 2002-04-17
US6103262A (en) 2000-08-15

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