DE69613975T2 - Dialkyltiacumicine - Google Patents

Dialkyltiacumicine

Info

Publication number
DE69613975T2
DE69613975T2 DE69613975T DE69613975T DE69613975T2 DE 69613975 T2 DE69613975 T2 DE 69613975T2 DE 69613975 T DE69613975 T DE 69613975T DE 69613975 T DE69613975 T DE 69613975T DE 69613975 T2 DE69613975 T2 DE 69613975T2
Authority
DE
Germany
Prior art keywords
dialkyltiacumicine
compounds
colitis
administration
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69613975T
Other languages
English (en)
Other versions
DE69613975D1 (de
Inventor
B Mcalpine
E Hochlowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69613975D1 publication Critical patent/DE69613975D1/de
Publication of DE69613975T2 publication Critical patent/DE69613975T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polymerisation Methods In General (AREA)
DE69613975T 1995-05-09 1996-05-02 Dialkyltiacumicine Expired - Fee Related DE69613975T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/437,761 US5583115A (en) 1995-05-09 1995-05-09 Dialkyltiacumicin compounds
PCT/US1996/006204 WO1996035702A1 (en) 1995-05-09 1996-05-02 Dialkyltiacumicin compounds

Publications (2)

Publication Number Publication Date
DE69613975D1 DE69613975D1 (de) 2001-08-23
DE69613975T2 true DE69613975T2 (de) 2002-04-04

Family

ID=23737769

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69613975T Expired - Fee Related DE69613975T2 (de) 1995-05-09 1996-05-02 Dialkyltiacumicine

Country Status (12)

Country Link
US (1) US5583115A (de)
EP (1) EP0824539B1 (de)
JP (1) JPH11504937A (de)
AT (1) ATE203246T1 (de)
CA (1) CA2218916A1 (de)
DE (1) DE69613975T2 (de)
DK (1) DK0824539T3 (de)
ES (1) ES2159733T3 (de)
GR (1) GR3036873T3 (de)
MX (1) MX9708611A (de)
PT (1) PT824539E (de)
WO (1) WO1996035702A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070105791A1 (en) * 2002-07-29 2007-05-10 Optimer Pharmaceuticals, Inc. Method of treating clostridium difficile-associated diarrhea
US7906489B2 (en) * 2004-05-14 2011-03-15 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof
ES2395404T3 (es) * 2004-05-14 2013-02-12 Optimer Pharmaceuticals, Inc. Tratamiento de las enfermedades asociadas al uso de antibióticos
MX340742B (es) * 2005-01-31 2016-07-21 Merck Sharp & Dohme Compuestos macrociclicos de 18 miembros y analogos de los mismos.
US7378508B2 (en) * 2007-01-22 2008-05-27 Optimer Pharmaceuticals, Inc. Polymorphic crystalline forms of tiacumicin B
WO2007048059A2 (en) * 2005-10-21 2007-04-26 Optimer Pharmaceuticals, Inc. Method of treating clostridium difficile-associated diarrhea
US20080176927A1 (en) * 2007-01-19 2008-07-24 Optimer Pharmaceuticals, Inc. Compositions of stable tiacumicins
ZA200905337B (en) * 2007-01-22 2010-10-27 Optimer Pharmaceuticals Inc Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof
TWI523654B (zh) 2007-11-27 2016-03-01 默沙東藥廠 抗生素巨環化合物以及其製造及使用之方法
JP5825217B2 (ja) * 2012-07-27 2015-12-02 メルク シャープ アンド ドーム コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． １８員大環状化合物及びその類似化合物
JO3464B1 (ar) 2013-01-15 2020-07-05 Astellas Pharma Europe Ltd التركيبات الخاصة بمركبات التياكوميسين
SI3139932T1 (sl) 2014-05-09 2018-12-31 Astellas Pharma Europe Ltd. Režim zdravljenja za spojino tiacumicina
CA2990961A1 (en) 2015-07-03 2017-01-12 Astellas Pharma Europe Ltd. Novel dosage regimen tiacumicin compound
EP3508492A1 (de) * 2018-01-08 2019-07-10 Universität Zürich Tiacumicinderivate und ihre verrwendung als antibiotika

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918174A (en) * 1986-09-26 1990-04-17 Abbott Laboratories Tiacumicin compounds

Also Published As

Publication number Publication date
CA2218916A1 (en) 1996-11-14
US5583115A (en) 1996-12-10
ATE203246T1 (de) 2001-08-15
PT824539E (pt) 2002-01-30
ES2159733T3 (es) 2001-10-16
EP0824539A1 (de) 1998-02-25
DK0824539T3 (da) 2001-09-24
JPH11504937A (ja) 1999-05-11
MX9708611A (es) 1998-02-28
WO1996035702A1 (en) 1996-11-14
GR3036873T3 (en) 2002-01-31
EP0824539B1 (de) 2001-07-18
DE69613975D1 (de) 2001-08-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee