DK0742834T4 - Fremgangsmåde til fremstilling af en virusvektor på mindst 20 kb ved intermolekylær homolog rekombination i en prokaryot celle - Google Patents
Fremgangsmåde til fremstilling af en virusvektor på mindst 20 kb ved intermolekylær homolog rekombination i en prokaryot celleInfo
- Publication number
- DK0742834T4 DK0742834T4 DK95941755T DK95941755T DK0742834T4 DK 0742834 T4 DK0742834 T4 DK 0742834T4 DK 95941755 T DK95941755 T DK 95941755T DK 95941755 T DK95941755 T DK 95941755T DK 0742834 T4 DK0742834 T4 DK 0742834T4
- Authority
- DK
- Denmark
- Prior art keywords
- homologous recombination
- producing
- virus vector
- prokaryotic cell
- vector
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9414470A FR2727689A1 (fr) | 1994-12-01 | 1994-12-01 | Nouveau procede de preparation d'un vecteur viral |
PCT/FR1995/001590 WO1996017070A1 (fr) | 1994-12-01 | 1995-12-01 | Procede de preparation d'un vecteur viral par recombinaison homologue intermoleculaire |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0742834T3 DK0742834T3 (da) | 2001-01-29 |
DK0742834T4 true DK0742834T4 (da) | 2005-08-22 |
Family
ID=9469390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95941755T DK0742834T4 (da) | 1994-12-01 | 1995-12-01 | Fremgangsmåde til fremstilling af en virusvektor på mindst 20 kb ved intermolekylær homolog rekombination i en prokaryot celle |
Country Status (13)
Country | Link |
---|---|
US (3) | US6110735A (pt) |
EP (1) | EP0742834B9 (pt) |
JP (1) | JP3989541B2 (pt) |
AT (1) | ATE196507T1 (pt) |
AU (1) | AU707208B2 (pt) |
CA (1) | CA2182303C (pt) |
DE (2) | DE69518910D1 (pt) |
DK (1) | DK0742834T4 (pt) |
ES (1) | ES2150595T5 (pt) |
FR (1) | FR2727689A1 (pt) |
GR (1) | GR3035050T3 (pt) |
PT (1) | PT742834E (pt) |
WO (1) | WO1996017070A1 (pt) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2727689A1 (fr) * | 1994-12-01 | 1996-06-07 | Transgene Sa | Nouveau procede de preparation d'un vecteur viral |
FR2730504B1 (fr) * | 1995-02-13 | 1997-03-28 | Rhone Poulenc Rorer Sa | Procede de preparation de genomes d'adenovirus recombinants |
US6720140B1 (en) * | 1995-06-07 | 2004-04-13 | Invitrogen Corporation | Recombinational cloning using engineered recombination sites |
US6143557A (en) | 1995-06-07 | 2000-11-07 | Life Technologies, Inc. | Recombination cloning using engineered recombination sites |
FR2761689B1 (fr) | 1997-04-02 | 1999-06-25 | Transgene Sa | Fibre adenovirale modifiee et adenovirus cibles |
DE69820450T2 (de) * | 1997-06-09 | 2004-05-27 | Genvec, Inc. | Chimäre vektoren, die die verpackungsregion eines phagengenoms und einen teil des genoms eines eukaryontischen virus enthalten |
FR2766091A1 (fr) | 1997-07-18 | 1999-01-22 | Transgene Sa | Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee |
CA2304173A1 (en) | 1997-09-23 | 1999-04-01 | Genvec, Inc. | Plasmids for construction of eukaryotic viral vectors |
CN100342008C (zh) * | 1997-10-24 | 2007-10-10 | 茵维特罗根公司 | 利用具重组位点的核酸进行重组克隆 |
CN101125873A (zh) * | 1997-10-24 | 2008-02-20 | 茵维特罗根公司 | 利用具重组位点的核酸进行重组克隆 |
US5922576A (en) * | 1998-02-27 | 1999-07-13 | The John Hopkins University | Simplified system for generating recombinant adenoviruses |
US6670188B1 (en) * | 1998-04-24 | 2003-12-30 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
US6413776B1 (en) | 1998-06-12 | 2002-07-02 | Galapagos Geonomics N.V. | High throughput screening of gene function using adenoviral libraries for functional genomics applications |
US7691370B2 (en) * | 1998-10-15 | 2010-04-06 | Canji, Inc. | Selectivity replicating viral vector |
CA2363924A1 (en) | 1999-03-02 | 2000-09-08 | Invitrogen Corporation | Compositions and methods for use in recombinational cloning of nucleic acids |
EP1248851A2 (en) * | 1999-12-07 | 2002-10-16 | Genethon III | Canine adenovirus vectors for the transfer of genes in targeted cells |
AU785483B2 (en) * | 1999-12-10 | 2007-09-20 | Invitrogen Corporation | Use of multiple recombination sites with unique specificity in recombinational cloning |
ES2394877T3 (es) * | 2000-08-14 | 2013-02-06 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Recombinación homóloga mejorada mediada por proteínas de recombinación de lambda |
US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
EP1337656A1 (en) * | 2000-11-10 | 2003-08-27 | AstraZeneca AB | In vitro generation of recombinant adenovirus vectors |
GB0027501D0 (en) * | 2000-11-10 | 2000-12-27 | Astrazeneca Ab | Vector |
WO2003051834A2 (en) * | 2001-12-14 | 2003-06-26 | President And Fellows Of Harvard College | Immunocellular receptors related to neurological disorders |
US7521242B2 (en) * | 2003-05-09 | 2009-04-21 | The United States Of America As Represented By The Department Of Health And Human Services | Host cells deficient for mismatch repair and their use in methods for inducing homologous recombination using single-stranded nucleic acids |
CN108486086A (zh) * | 2003-07-02 | 2018-09-04 | 维莱尼姆公司 | 葡聚糖酶,编码它们的核酸以及制备和使用它们的方法 |
ATE405654T1 (de) | 2003-07-21 | 2008-09-15 | Transgene Sa | Polypeptid mit verbesserter cytosin-deaminase- aktivität |
EP1925626A1 (en) | 2003-07-21 | 2008-05-28 | Transgene S.A. | Novel multifunctional cytokines |
DE602004027538D1 (de) | 2003-12-01 | 2010-07-15 | Life Technologies Corp | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
US7674621B2 (en) * | 2004-05-21 | 2010-03-09 | The United States Of America As Represented By The Department Of Health And Human Services | Plasmids and phages for homologous recombination and methods of use |
US20060234347A1 (en) * | 2005-04-13 | 2006-10-19 | Harding Thomas C | Targeting multiple angiogenic pathways for cancer therapy using soluble tyrosine kinase receptors |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
DK2068918T4 (da) | 2006-09-26 | 2024-09-02 | Access To Advanced Health Inst | Vaccinesammensætning omfattende syntetisk adjuvant |
ATE518958T1 (de) | 2007-01-30 | 2011-08-15 | Transgene Sa | Zur impfung verwendetes papillomavirus-e2- polypeptid |
US8470977B2 (en) | 2008-03-14 | 2013-06-25 | Transgene S.A. | Antibody against the CSF-1R |
BRPI1006179A2 (pt) | 2009-01-13 | 2016-02-23 | Transgène S A | uso de uma fração de ácidos nucleicos mitocondriais, composição adjuvante, composição de vacina, e, kit da parte |
KR20110116016A (ko) | 2009-01-20 | 2011-10-24 | 트랜스진 에스.에이. | 치료적 반응의 예측을 위한 바이오마커로서의 가용성 icam―1 |
US20120028279A1 (en) | 2009-03-24 | 2012-02-02 | Bruce Acres | Biomarker for monitoring patients |
PT2419728E (pt) | 2009-04-17 | 2014-03-12 | Transgene Sa | Marcadores biológicos para monitorizar doentes |
EP3124491B1 (en) * | 2009-06-05 | 2019-10-30 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants and vaccine compositions as well as pharmaceutical compositions containing them |
US20110015256A1 (en) * | 2009-07-16 | 2011-01-20 | Ihab Mamdouh Ishak Sadek | Delivery of restriction endonucleases to treat hiv, cancer, and other medical conditions |
US9393299B2 (en) | 2009-08-07 | 2016-07-19 | Transgene S.A. | Composition for treating HBV infection |
JP6054942B2 (ja) | 2011-04-08 | 2016-12-27 | イミューン デザイン コーポレイション | 免疫原性組成物、ならびに体液性および細胞性免疫応答を誘発するための該組成物の使用方法 |
PL2811981T3 (pl) | 2012-02-07 | 2019-09-30 | Infectious Disease Research Institute | Ulepszone formulacje adiuwantowe zawierające agonistę TLR4 oraz sposoby ich zastosowania |
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CN109134640A (zh) | 2012-10-23 | 2019-01-04 | 爱默蕾大学 | Gm-csf和il-4轭合物、组合物以及与其相关的方法 |
BR112015025709A2 (pt) | 2013-04-18 | 2017-07-18 | Immune Design Corp | monoterapia com gla para uso em tratamento de câncer |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
EP3452081A1 (en) | 2016-05-04 | 2019-03-13 | Transgene SA | Combination therapy with cpg tlr9 ligand |
ES2929054T3 (es) | 2016-05-16 | 2022-11-24 | Access To Advanced Health Inst | Formulación que contiene un agonista de TLR y métodos de uso |
WO2017210364A1 (en) | 2016-06-01 | 2017-12-07 | Infectious Disease Research Institute | Nanoalum particles containing a sizing agent |
KR102566066B1 (ko) | 2016-09-20 | 2023-08-16 | 베링거잉겔하임베트메디카게엠베하 | 신규한 돼지 인플루엔자 백신 |
WO2018057441A1 (en) | 2016-09-20 | 2018-03-29 | Boehringer Ingelheim Vetmedica Gmbh | Canine adenovirus vectors |
BR112019005418A2 (pt) | 2016-09-20 | 2019-10-01 | Boehringer Ingelheim Vetmedica Gmbh | novos promotores |
KR102618843B1 (ko) | 2016-09-20 | 2024-01-02 | 베링거잉겔하임베트메디카게엠베하 | 신규한 ehv 삽입 부위 orf70 |
US20190328869A1 (en) | 2016-10-10 | 2019-10-31 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
CA3044074A1 (en) | 2016-11-16 | 2018-05-24 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
CN110799529A (zh) | 2017-04-22 | 2020-02-14 | 免疫治疗有限公司 | 改良lamp构建物 |
BR112019023014A2 (pt) | 2017-05-02 | 2020-05-19 | Immunomic Therapeutics Inc | constructos de lamp aperfeiçoados compreendendo antígenos de câncer |
WO2019051149A1 (en) | 2017-09-08 | 2019-03-14 | Infectious Disease Research Institute | LIPOSOMAL FORMULATIONS COMPRISING SAPONIN AND METHODS OF USE |
JP2021523185A (ja) | 2018-05-15 | 2021-09-02 | イミュノミック セラピューティックス, インコーポレイテッドImmunomic Therapeutics, Inc. | アレルゲンを含む改善されたlamp構築物 |
CN113573729A (zh) | 2019-01-10 | 2021-10-29 | 詹森生物科技公司 | 前列腺新抗原及其用途 |
CN114761546A (zh) | 2019-10-08 | 2022-07-15 | 波士顿学院董事会 | 含有多个不同非天然氨基酸的蛋白质以及制备和使用此类蛋白质的方法 |
CN114641306A (zh) | 2019-10-18 | 2022-06-17 | 免疫治疗有限公司 | 包含癌抗原的改良lamp构建物 |
IL293051A (en) | 2019-11-18 | 2022-07-01 | Janssen Biotech Inc | calr and jak2 mutant-based vaccines and their uses |
TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
CN115484978A (zh) | 2020-03-05 | 2022-12-16 | 尼奥克斯医疗有限公司 | 使用免疫细胞治疗癌症的方法和组合物 |
WO2021209897A1 (en) | 2020-04-13 | 2021-10-21 | Janssen Biotech, Inc. | Psma and steap1 vaccines and their uses |
WO2022009051A1 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | A method for determining responsiveness to prostate cancer treatment |
US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
EP4175664A2 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
AU2023254186A1 (en) | 2022-04-10 | 2024-10-17 | Immunomic Therapeutics, Inc. | Bicistronic lamp constructs comprising immune response enhancing genes and methods of use thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
GB9001766D0 (en) * | 1990-01-25 | 1990-03-28 | Univ Court Of The University O | Vaccines |
FR2705361B1 (fr) | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
WO1995003400A1 (en) * | 1993-07-23 | 1995-02-02 | Johns Hopkins University School Of Medicine | Recombinationally targeted cloning in yeast artificial chromosomes |
FR2727689A1 (fr) * | 1994-12-01 | 1996-06-07 | Transgene Sa | Nouveau procede de preparation d'un vecteur viral |
US5582362A (en) * | 1995-03-31 | 1996-12-10 | Johnson; John R. | Center feed toilet paper dispenser |
-
1994
- 1994-12-01 FR FR9414470A patent/FR2727689A1/fr active Granted
-
1995
- 1995-12-01 WO PCT/FR1995/001590 patent/WO1996017070A1/fr active IP Right Grant
- 1995-12-01 EP EP95941755A patent/EP0742834B9/fr not_active Expired - Lifetime
- 1995-12-01 ES ES95941755T patent/ES2150595T5/es not_active Expired - Lifetime
- 1995-12-01 JP JP51834696A patent/JP3989541B2/ja not_active Expired - Lifetime
- 1995-12-01 AU AU43068/96A patent/AU707208B2/en not_active Expired
- 1995-12-01 DE DE69518910A patent/DE69518910D1/de not_active Expired - Lifetime
- 1995-12-01 PT PT95941755T patent/PT742834E/pt unknown
- 1995-12-01 AT AT95941755T patent/ATE196507T1/de active
- 1995-12-01 CA CA002182303A patent/CA2182303C/fr not_active Expired - Lifetime
- 1995-12-01 DK DK95941755T patent/DK0742834T4/da active
- 1995-12-01 DE DE69518910T patent/DE69518910T3/de not_active Expired - Lifetime
- 1995-12-01 US US08/682,794 patent/US6110735A/en not_active Expired - Lifetime
-
1999
- 1999-12-21 US US09/467,952 patent/US6281000B1/en not_active Expired - Lifetime
-
2000
- 2000-12-12 GR GR20000402737T patent/GR3035050T3/el unknown
-
2001
- 2001-08-27 US US09/938,491 patent/US7067310B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69518910D1 (de) | 2000-10-26 |
EP0742834A1 (fr) | 1996-11-20 |
US20020090715A1 (en) | 2002-07-11 |
DE69518910T2 (de) | 2001-03-29 |
CA2182303C (fr) | 2005-06-21 |
EP0742834B2 (fr) | 2005-08-03 |
DK0742834T3 (da) | 2001-01-29 |
FR2727689A1 (fr) | 1996-06-07 |
ES2150595T5 (es) | 2005-12-01 |
EP0742834B9 (fr) | 2005-12-28 |
JP3989541B2 (ja) | 2007-10-10 |
AU707208B2 (en) | 1999-07-08 |
US7067310B2 (en) | 2006-06-27 |
US6110735A (en) | 2000-08-29 |
FR2727689B1 (pt) | 1997-02-28 |
PT742834E (pt) | 2001-03-30 |
GR3035050T3 (en) | 2001-03-30 |
DE69518910T4 (de) | 2006-02-09 |
US6281000B1 (en) | 2001-08-28 |
WO1996017070A1 (fr) | 1996-06-06 |
ES2150595T3 (es) | 2000-12-01 |
EP0742834B1 (fr) | 2000-09-20 |
ATE196507T1 (de) | 2000-10-15 |
JPH09509330A (ja) | 1997-09-22 |
DE69518910T3 (de) | 2006-07-13 |
AU4306896A (en) | 1996-06-19 |
CA2182303A1 (fr) | 1996-06-06 |
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