DK0736009T3 - N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter - Google Patents
N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenterInfo
- Publication number
- DK0736009T3 DK0736009T3 DK95906100T DK95906100T DK0736009T3 DK 0736009 T3 DK0736009 T3 DK 0736009T3 DK 95906100 T DK95906100 T DK 95906100T DK 95906100 T DK95906100 T DK 95906100T DK 0736009 T3 DK0736009 T3 DK 0736009T3
- Authority
- DK
- Denmark
- Prior art keywords
- arylpiperidines
- arylpiperazines
- oxides
- antipsychotic drugs
- antipsychotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17338293A | 1993-12-23 | 1993-12-23 | |
PCT/US1994/014850 WO1995017385A1 (en) | 1993-12-23 | 1994-12-22 | N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0736009T3 true DK0736009T3 (da) | 2002-10-07 |
Family
ID=22631753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95906100T DK0736009T3 (da) | 1993-12-23 | 1994-12-22 | N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0736009B1 (ru) |
JP (1) | JPH09507077A (ru) |
AT (1) | ATE223898T1 (ru) |
AU (1) | AU687501B2 (ru) |
CA (1) | CA2179735A1 (ru) |
DE (1) | DE69431360T2 (ru) |
DK (1) | DK0736009T3 (ru) |
ES (1) | ES2183862T3 (ru) |
IL (1) | IL112099A (ru) |
MX (1) | MX9500228A (ru) |
NZ (1) | NZ278261A (ru) |
PT (1) | PT736009E (ru) |
RU (1) | RU2123001C1 (ru) |
SI (1) | SI0736009T1 (ru) |
WO (1) | WO1995017385A1 (ru) |
ZA (1) | ZA9410287B (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
BR0113167A (pt) * | 2000-08-11 | 2003-06-24 | Ono Pharmaceutical Co | Derivados de piperidina e agente que compreende o derivado como ingrediente ativo |
CA2526209A1 (en) | 2003-06-12 | 2004-12-23 | Btg International Limited | Cyclic hydroxylamine as psychoactive compounds |
CN101711236B (zh) * | 2007-04-12 | 2012-10-31 | Nsab神经研究瑞典公司分公司 | 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 |
EP2787997A4 (en) | 2011-12-08 | 2015-05-27 | Ivax Int Gmbh | HYDROBROMIDE SALT OF PRIDOPIDINE |
EA027748B1 (ru) | 2012-04-04 | 2017-08-31 | Тева Фармасьютикалз Интернэшнл Гмбх | Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения |
EP3236964A4 (en) | 2014-12-22 | 2018-09-19 | Teva Pharmaceuticals International GmbH | L-tartrate salt of pridopidine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ240863A (en) * | 1991-09-11 | 1995-04-27 | Mcneilab Inc | Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof |
FR2697251B1 (fr) * | 1992-10-22 | 1994-12-02 | Synthelabo | N-oxydes de dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl] pipéridin-1-yl]éthanol, leur procédé de préparation et leur application en thérapeutique. |
-
1994
- 1994-12-21 IL IL11209994A patent/IL112099A/xx not_active IP Right Cessation
- 1994-12-22 PT PT95906100T patent/PT736009E/pt unknown
- 1994-12-22 AT AT95906100T patent/ATE223898T1/de not_active IP Right Cessation
- 1994-12-22 DK DK95906100T patent/DK0736009T3/da active
- 1994-12-22 DE DE69431360T patent/DE69431360T2/de not_active Expired - Fee Related
- 1994-12-22 RU RU96115155A patent/RU2123001C1/ru not_active IP Right Cessation
- 1994-12-22 CA CA002179735A patent/CA2179735A1/en not_active Abandoned
- 1994-12-22 EP EP95906100A patent/EP0736009B1/en not_active Expired - Lifetime
- 1994-12-22 AU AU14446/95A patent/AU687501B2/en not_active Ceased
- 1994-12-22 ZA ZA9410287A patent/ZA9410287B/xx unknown
- 1994-12-22 NZ NZ278261A patent/NZ278261A/en unknown
- 1994-12-22 WO PCT/US1994/014850 patent/WO1995017385A1/en active IP Right Grant
- 1994-12-22 JP JP7517623A patent/JPH09507077A/ja not_active Ceased
- 1994-12-22 ES ES95906100T patent/ES2183862T3/es not_active Expired - Lifetime
- 1994-12-22 SI SI9430427T patent/SI0736009T1/xx unknown
-
1995
- 1995-01-02 MX MX9500228A patent/MX9500228A/es not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU1444695A (en) | 1995-07-10 |
PT736009E (pt) | 2003-01-31 |
ES2183862T3 (es) | 2003-04-01 |
MX9500228A (es) | 1997-02-28 |
DE69431360T2 (de) | 2003-01-23 |
IL112099A (en) | 1999-07-14 |
EP0736009B1 (en) | 2002-09-11 |
SI0736009T1 (en) | 2003-04-30 |
CA2179735A1 (en) | 1995-06-29 |
AU687501B2 (en) | 1998-02-26 |
NZ278261A (en) | 1998-08-26 |
EP0736009A1 (en) | 1996-10-09 |
DE69431360D1 (de) | 2002-10-17 |
JPH09507077A (ja) | 1997-07-15 |
IL112099A0 (en) | 1995-03-15 |
RU2123001C1 (ru) | 1998-12-10 |
ATE223898T1 (de) | 2002-09-15 |
ZA9410287B (en) | 1996-06-24 |
WO1995017385A1 (en) | 1995-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0563345T3 (da) | Nye 4-arylpiperaziner og 4-arylpiperidiner | |
DK0559019T3 (da) | 14-beta-hydroxy-10-deacetyl-baccatin III og derivater deraf som antitumormidler | |
PT789578E (pt) | Inibidores da protease multicatalitica | |
AU6787390A (en) | Nitrogen-containing spirocycles | |
ATE226201T1 (de) | Substituierte pyridylpyrazole | |
DK0481522T3 (da) | Nye mercaptoacetylamid-derivater anvendelige som inhibitorer af enkephalinase og ACE | |
TR199800011T1 (xx) | Benzo$g] kuinolin t�revleri | |
DK1097173T3 (da) | Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler | |
KR960702830A (ko) | 방사선 보호제로서의 N-알킬티오 폴리아민 유도체(N-Alkylthio polyaine derivatives as radioprotective agents) | |
NO952205L (no) | Heterocykliske karbamater, fremgangsmåte for fremstilling derav og medikamenter | |
DK0638068T3 (da) | Fremgangsmåde til fremstilling af (S)-3-amino-1-substitueret-pyrrolidiner | |
DK0736009T3 (da) | N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter | |
FI955118A0 (fi) | Herbisidiset substituoidut 1-fenyyli- tai 1-pyridinyyli-bentsotriatsolit | |
ES2104174T3 (es) | Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos. | |
TR199701298T1 (xx) | Tetralinler. | |
DE60030710D1 (de) | Freisetzungsregulierende zubereitungen | |
UY24326A1 (es) | Nuevas piperidinas. | |
DK0779075T3 (da) | Anvendelse af 3-alpha-hydroxy-5-alpha-androsta-16-en som lægemidler |