SI0736009T1 - N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs - Google Patents
N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugsInfo
- Publication number
- SI0736009T1 SI0736009T1 SI9430427T SI9430427T SI0736009T1 SI 0736009 T1 SI0736009 T1 SI 0736009T1 SI 9430427 T SI9430427 T SI 9430427T SI 9430427 T SI9430427 T SI 9430427T SI 0736009 T1 SI0736009 T1 SI 0736009T1
- Authority
- SI
- Slovenia
- Prior art keywords
- arylpiperidines
- arylpiperazines
- oxides
- antipsychotic drugs
- antipsychotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17338293A | 1993-12-23 | 1993-12-23 | |
| EP95906100A EP0736009B1 (en) | 1993-12-23 | 1994-12-22 | N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs |
| PCT/US1994/014850 WO1995017385A1 (en) | 1993-12-23 | 1994-12-22 | N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0736009T1 true SI0736009T1 (en) | 2003-04-30 |
Family
ID=22631753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9430427T SI0736009T1 (en) | 1993-12-23 | 1994-12-22 | N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0736009B1 (ru) |
| JP (1) | JPH09507077A (ru) |
| AT (1) | ATE223898T1 (ru) |
| AU (1) | AU687501B2 (ru) |
| CA (1) | CA2179735A1 (ru) |
| DE (1) | DE69431360T2 (ru) |
| DK (1) | DK0736009T3 (ru) |
| ES (1) | ES2183862T3 (ru) |
| IL (1) | IL112099A (ru) |
| MX (1) | MX9500228A (ru) |
| NZ (1) | NZ278261A (ru) |
| PT (1) | PT736009E (ru) |
| RU (1) | RU2123001C1 (ru) |
| SI (1) | SI0736009T1 (ru) |
| WO (1) | WO1995017385A1 (ru) |
| ZA (1) | ZA9410287B (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| NZ524050A (en) * | 2000-08-11 | 2005-07-29 | Ono Pharmaceutical Co | Piperidine derivatives in compounds that have a PDE4 inhibitory activity to treat inflammatory conditions |
| KR20060018253A (ko) | 2003-06-12 | 2006-02-28 | 비티지 인터내셔널 리미티드 | 정신작용 화합물로서의 시클릭 히드록실아민 |
| JP5393654B2 (ja) * | 2007-04-12 | 2014-01-22 | イヴァックス インテルナツィオナール ゲゼルシャフト ミット ベシュレンクテル ハフツンク | 改善された心血管副作用プロフィールを呈する、ドーパミン受容体安定剤／調節剤のｎ−オキシド誘導体及び／又はジ−ｎ−オキシド誘導体 |
| UY34503A (es) | 2011-12-08 | 2013-07-31 | Ivax Int Gmbh | ?sal de bromhidrato de pridopidina? |
| WO2013152105A1 (en) | 2012-04-04 | 2013-10-10 | IVAX International GmbH | Pharmaceutical compositions for combination therapy |
| EP3236964A4 (en) | 2014-12-22 | 2018-09-19 | Teva Pharmaceuticals International GmbH | L-tartrate salt of pridopidine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ240863A (en) * | 1991-09-11 | 1995-04-27 | Mcneilab Inc | Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof |
| FR2697251B1 (fr) * | 1992-10-22 | 1994-12-02 | Synthelabo | N-oxydes de dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl] pipéridin-1-yl]éthanol, leur procédé de préparation et leur application en thérapeutique. |
-
1994
- 1994-12-21 IL IL11209994A patent/IL112099A/xx not_active IP Right Cessation
- 1994-12-22 SI SI9430427T patent/SI0736009T1/xx unknown
- 1994-12-22 NZ NZ278261A patent/NZ278261A/en unknown
- 1994-12-22 EP EP95906100A patent/EP0736009B1/en not_active Expired - Lifetime
- 1994-12-22 DE DE69431360T patent/DE69431360T2/de not_active Expired - Fee Related
- 1994-12-22 ZA ZA9410287A patent/ZA9410287B/xx unknown
- 1994-12-22 CA CA002179735A patent/CA2179735A1/en not_active Abandoned
- 1994-12-22 AT AT95906100T patent/ATE223898T1/de not_active IP Right Cessation
- 1994-12-22 JP JP7517623A patent/JPH09507077A/ja not_active Ceased
- 1994-12-22 WO PCT/US1994/014850 patent/WO1995017385A1/en active IP Right Grant
- 1994-12-22 PT PT95906100T patent/PT736009E/pt unknown
- 1994-12-22 RU RU96115155A patent/RU2123001C1/ru not_active IP Right Cessation
- 1994-12-22 AU AU14446/95A patent/AU687501B2/en not_active Ceased
- 1994-12-22 ES ES95906100T patent/ES2183862T3/es not_active Expired - Lifetime
- 1994-12-22 DK DK95906100T patent/DK0736009T3/da active
-
1995
- 1995-01-02 MX MX9500228A patent/MX9500228A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL112099A (en) | 1999-07-14 |
| WO1995017385A1 (en) | 1995-06-29 |
| PT736009E (pt) | 2003-01-31 |
| EP0736009A1 (en) | 1996-10-09 |
| CA2179735A1 (en) | 1995-06-29 |
| MX9500228A (es) | 1997-02-28 |
| DE69431360T2 (de) | 2003-01-23 |
| NZ278261A (en) | 1998-08-26 |
| RU2123001C1 (ru) | 1998-12-10 |
| AU1444695A (en) | 1995-07-10 |
| EP0736009B1 (en) | 2002-09-11 |
| AU687501B2 (en) | 1998-02-26 |
| DE69431360D1 (de) | 2002-10-17 |
| DK0736009T3 (da) | 2002-10-07 |
| ZA9410287B (en) | 1996-06-24 |
| JPH09507077A (ja) | 1997-07-15 |
| ATE223898T1 (de) | 2002-09-15 |
| IL112099A0 (en) | 1995-03-15 |
| ES2183862T3 (es) | 2003-04-01 |
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