PT736009E - N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos - Google Patents

N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos

Info

Publication number
PT736009E
PT736009E PT95906100T PT95906100T PT736009E PT 736009 E PT736009 E PT 736009E PT 95906100 T PT95906100 T PT 95906100T PT 95906100 T PT95906100 T PT 95906100T PT 736009 E PT736009 E PT 736009E
Authority
PT
Portugal
Prior art keywords
arylipypherazines
arylippyridines
oxides
psychotic drugs
psychotic
Prior art date
Application number
PT95906100T
Other languages
English (en)
Inventor
Mark E Mcdonnell
Allen B Reitz
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of PT736009E publication Critical patent/PT736009E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT95906100T 1993-12-23 1994-12-22 N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos PT736009E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17338293A 1993-12-23 1993-12-23

Publications (1)

Publication Number Publication Date
PT736009E true PT736009E (pt) 2003-01-31

Family

ID=22631753

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95906100T PT736009E (pt) 1993-12-23 1994-12-22 N-oxidos de 4-arilpiperazinas e 4-arilpiperidinas como farmacos antipsicoticos

Country Status (16)

Country Link
EP (1) EP0736009B1 (pt)
JP (1) JPH09507077A (pt)
AT (1) ATE223898T1 (pt)
AU (1) AU687501B2 (pt)
CA (1) CA2179735A1 (pt)
DE (1) DE69431360T2 (pt)
DK (1) DK0736009T3 (pt)
ES (1) ES2183862T3 (pt)
IL (1) IL112099A (pt)
MX (1) MX9500228A (pt)
NZ (1) NZ278261A (pt)
PT (1) PT736009E (pt)
RU (1) RU2123001C1 (pt)
SI (1) SI0736009T1 (pt)
WO (1) WO1995017385A1 (pt)
ZA (1) ZA9410287B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
BR0113167A (pt) * 2000-08-11 2003-06-24 Ono Pharmaceutical Co Derivados de piperidina e agente que compreende o derivado como ingrediente ativo
CA2526209A1 (en) 2003-06-12 2004-12-23 Btg International Limited Cyclic hydroxylamine as psychoactive compounds
EP2146961B1 (en) * 2007-04-12 2014-01-29 IVAX International GmbH N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles
US9012476B2 (en) 2011-12-08 2015-04-21 IVAX International GmbH Hydrobromide salt of pridopidine
EA027748B1 (ru) 2012-04-04 2017-08-31 Тева Фармасьютикалз Интернэшнл Гмбх Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения
JP2018505147A (ja) 2014-12-22 2018-02-22 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハー プリドピジンのｌ−酒石酸塩

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE914218A1 (en) * 1991-09-11 1993-03-24 Mcneilab Inc Novel 4-arylpiperazines and 4-arylpiperidines
FR2697251B1 (fr) * 1992-10-22 1994-12-02 Synthelabo N-oxydes de dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl] pipéridin-1-yl]éthanol, leur procédé de préparation et leur application en thérapeutique.

Also Published As

Publication number Publication date
SI0736009T1 (en) 2003-04-30
AU1444695A (en) 1995-07-10
EP0736009A1 (en) 1996-10-09
ZA9410287B (en) 1996-06-24
DE69431360T2 (de) 2003-01-23
EP0736009B1 (en) 2002-09-11
DK0736009T3 (da) 2002-10-07
NZ278261A (en) 1998-08-26
DE69431360D1 (de) 2002-10-17
RU2123001C1 (ru) 1998-12-10
AU687501B2 (en) 1998-02-26
ES2183862T3 (es) 2003-04-01
ATE223898T1 (de) 2002-09-15
IL112099A (en) 1999-07-14
MX9500228A (es) 1997-02-28
WO1995017385A1 (en) 1995-06-29
JPH09507077A (ja) 1997-07-15
CA2179735A1 (en) 1995-06-29
IL112099A0 (en) 1995-03-15

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