DK0678025T3 - Transdermal behandling af cancer med vand-ouopløslig S-camptothecin af den lukkede lactonringform - Google Patents
Transdermal behandling af cancer med vand-ouopløslig S-camptothecin af den lukkede lactonringformInfo
- Publication number
- DK0678025T3 DK0678025T3 DK94907804T DK94907804T DK0678025T3 DK 0678025 T3 DK0678025 T3 DK 0678025T3 DK 94907804 T DK94907804 T DK 94907804T DK 94907804 T DK94907804 T DK 94907804T DK 0678025 T3 DK0678025 T3 DK 0678025T3
- Authority
- DK
- Denmark
- Prior art keywords
- camptothecin
- insoluble
- water
- lactone ring
- cancer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US284493A | 1993-01-15 | 1993-01-15 | |
| PCT/US1994/000403 WO1994015604A1 (en) | 1993-01-15 | 1994-01-14 | Transdermal treatment of cancer with water-insoluble s-camptothecin of the closed lactone ring form |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0678025T3 true DK0678025T3 (da) | 1998-10-07 |
Family
ID=21702794
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97101631T DK0778024T3 (da) | 1993-01-15 | 1994-01-14 | Oral eller intramuskulær behandling af pancreascancer med vanduopløselig S-camptothecin i lukket lactonring-formen |
| DK02015200T DK1250926T3 (da) | 1993-01-15 | 1994-01-14 | Anvendelse af vanduoplöseligt S-camptothecin med en lukket lactonring i fremstilling af et medikament til behandling af coloncancer |
| DK94907804T DK0678025T3 (da) | 1993-01-15 | 1994-01-14 | Transdermal behandling af cancer med vand-ouopløslig S-camptothecin af den lukkede lactonringform |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97101631T DK0778024T3 (da) | 1993-01-15 | 1994-01-14 | Oral eller intramuskulær behandling af pancreascancer med vanduopløselig S-camptothecin i lukket lactonring-formen |
| DK02015200T DK1250926T3 (da) | 1993-01-15 | 1994-01-14 | Anvendelse af vanduoplöseligt S-camptothecin med en lukket lactonring i fremstilling af et medikament til behandling af coloncancer |
Country Status (9)
| Country | Link |
|---|---|
| EP (3) | EP1250926B1 (da) |
| JP (1) | JP3099128B2 (da) |
| AT (3) | ATE227573T1 (da) |
| CA (1) | CA2148822C (da) |
| DE (3) | DE69435084T2 (da) |
| DK (3) | DK0778024T3 (da) |
| ES (3) | ES2301590T3 (da) |
| PT (1) | PT1250926E (da) |
| WO (1) | WO1994015604A1 (da) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5244903A (en) * | 1987-03-31 | 1993-09-14 | Research Triangle Institute | Camptothecin analogs as potent inhibitors of topoisomerase I |
| ATE211142T1 (de) * | 1989-09-15 | 2002-01-15 | Res Triangle Inst | Verfahren zur herstellung von 10,11-methylendioxy-20(rs)-camptothecin und 10,11-methylendioxy-20(s)-camptothecin-analog |
| US5422344A (en) * | 1990-05-08 | 1995-06-06 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Method of treating retroviral infections in mammals |
| ATE136898T1 (de) * | 1991-10-29 | 1996-05-15 | Glaxo Wellcome Inc | Wasserlösliche camptothecinderivate |
| EP1393730A3 (en) * | 1991-11-15 | 2004-03-17 | Smithkline Beecham Corporation | Combination chemotherapy involving topotecan and a platinum coordination compound |
| CA2125293A1 (en) * | 1991-12-10 | 1993-06-24 | Randall Keith Johnson | Treatment of colorectal cancer |
-
1994
- 1994-01-14 ES ES02015200T patent/ES2301590T3/es not_active Expired - Lifetime
- 1994-01-14 AT AT97101631T patent/ATE227573T1/de not_active IP Right Cessation
- 1994-01-14 EP EP02015200A patent/EP1250926B1/en not_active Expired - Lifetime
- 1994-01-14 PT PT02015200T patent/PT1250926E/pt unknown
- 1994-01-14 AT AT02015200T patent/ATE388706T1/de not_active IP Right Cessation
- 1994-01-14 AT AT94907804T patent/ATE165003T1/de not_active IP Right Cessation
- 1994-01-14 JP JP06516305A patent/JP3099128B2/ja not_active Expired - Fee Related
- 1994-01-14 DE DE69435084T patent/DE69435084T2/de not_active Expired - Fee Related
- 1994-01-14 CA CA002148822A patent/CA2148822C/en not_active Expired - Fee Related
- 1994-01-14 DE DE69409633T patent/DE69409633T2/de not_active Expired - Fee Related
- 1994-01-14 WO PCT/US1994/000403 patent/WO1994015604A1/en active IP Right Grant
- 1994-01-14 ES ES94907804T patent/ES2114681T3/es not_active Expired - Lifetime
- 1994-01-14 DK DK97101631T patent/DK0778024T3/da active
- 1994-01-14 ES ES97101631T patent/ES2186812T3/es not_active Expired - Lifetime
- 1994-01-14 DE DE69431731T patent/DE69431731T2/de not_active Expired - Fee Related
- 1994-01-14 EP EP94907804A patent/EP0678025B1/en not_active Expired - Lifetime
- 1994-01-14 DK DK02015200T patent/DK1250926T3/da active
- 1994-01-14 EP EP97101631A patent/EP0778024B1/en not_active Expired - Lifetime
- 1994-01-14 DK DK94907804T patent/DK0678025T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0678025A1 (en) | 1995-10-25 |
| DE69431731T2 (de) | 2003-03-13 |
| ATE165003T1 (de) | 1998-05-15 |
| EP0778024B1 (en) | 2002-11-13 |
| DE69431731D1 (de) | 2002-12-19 |
| WO1994015604A1 (en) | 1994-07-21 |
| ES2186812T3 (es) | 2003-05-16 |
| JPH08505626A (ja) | 1996-06-18 |
| EP1250926B1 (en) | 2008-03-12 |
| JP3099128B2 (ja) | 2000-10-16 |
| EP0778024A1 (en) | 1997-06-11 |
| DE69435084D1 (de) | 2008-04-24 |
| DK1250926T3 (da) | 2008-07-07 |
| PT1250926E (pt) | 2008-06-11 |
| DK0778024T3 (da) | 2002-12-23 |
| ES2301590T3 (es) | 2008-07-01 |
| CA2148822A1 (en) | 1994-07-21 |
| ATE227573T1 (de) | 2002-11-15 |
| EP0678025B1 (en) | 1998-04-15 |
| EP1250926A2 (en) | 2002-10-23 |
| DE69409633D1 (de) | 1998-05-20 |
| DE69435084T2 (de) | 2009-03-19 |
| ES2114681T3 (es) | 1998-06-01 |
| CA2148822C (en) | 2001-03-27 |
| DE69409633T2 (de) | 1998-08-06 |
| ATE388706T1 (de) | 2008-03-15 |
| EP1250926A3 (en) | 2002-11-20 |
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