ATE165003T1 - Transdermal behandlung von krebs mit wasserunlöslichem s-camtothecin mit geschlossenem lactoring - Google Patents

Transdermal behandlung von krebs mit wasserunlöslichem s-camtothecin mit geschlossenem lactoring

Info

Publication number
ATE165003T1
ATE165003T1 AT94907804T AT94907804T ATE165003T1 AT E165003 T1 ATE165003 T1 AT E165003T1 AT 94907804 T AT94907804 T AT 94907804T AT 94907804 T AT94907804 T AT 94907804T AT E165003 T1 ATE165003 T1 AT E165003T1
Authority
AT
Austria
Prior art keywords
camptothecin
insoluble
water
closed
cancer
Prior art date
Application number
AT94907804T
Other languages
English (en)
Inventor
Beppino C Giovanella
Hellmuth R Hinz
Anthony J Kozielski
John S Stehlin
Original Assignee
Stehlin Foundation For Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stehlin Foundation For Cancer filed Critical Stehlin Foundation For Cancer
Application granted granted Critical
Publication of ATE165003T1 publication Critical patent/ATE165003T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT94907804T 1993-01-15 1994-01-14 Transdermal behandlung von krebs mit wasserunlöslichem s-camtothecin mit geschlossenem lactoring ATE165003T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US284493A 1993-01-15 1993-01-15

Publications (1)

Publication Number Publication Date
ATE165003T1 true ATE165003T1 (de) 1998-05-15

Family

ID=21702794

Family Applications (3)

Application Number Title Priority Date Filing Date
AT97101631T ATE227573T1 (de) 1993-01-15 1994-01-14 Orale oder intramuskuläre behandlung von pankreaskrebs durch wasserunlösliches s- camptothecin mit geschlossenem lactonring
AT94907804T ATE165003T1 (de) 1993-01-15 1994-01-14 Transdermal behandlung von krebs mit wasserunlöslichem s-camtothecin mit geschlossenem lactoring
AT02015200T ATE388706T1 (de) 1993-01-15 1994-01-14 Die verwendung von wasserunlöslichem s- camptothecin mit geschlossenem lactonring für die herstellung eines medikamentes zur behandlung von darmkrebs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97101631T ATE227573T1 (de) 1993-01-15 1994-01-14 Orale oder intramuskuläre behandlung von pankreaskrebs durch wasserunlösliches s- camptothecin mit geschlossenem lactonring

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02015200T ATE388706T1 (de) 1993-01-15 1994-01-14 Die verwendung von wasserunlöslichem s- camptothecin mit geschlossenem lactonring für die herstellung eines medikamentes zur behandlung von darmkrebs

Country Status (9)

Country Link
EP (3) EP0778024B1 (de)
JP (1) JP3099128B2 (de)
AT (3) ATE227573T1 (de)
CA (1) CA2148822C (de)
DE (3) DE69435084T2 (de)
DK (3) DK1250926T3 (de)
ES (3) ES2114681T3 (de)
PT (1) PT1250926E (de)
WO (1) WO1994015604A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244903A (en) * 1987-03-31 1993-09-14 Research Triangle Institute Camptothecin analogs as potent inhibitors of topoisomerase I
DK0418099T3 (da) * 1989-09-15 2002-04-02 Res Triangle Inst Fremgangsmåde til fremstilling af 10,11-methylendioxy-20(RS)-camptothecin og 10,11-methylendioxy-20(S)-camptothecinanaloger
US5422344A (en) * 1990-05-08 1995-06-06 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Method of treating retroviral infections in mammals
DE69209969T2 (de) * 1991-10-29 1996-09-12 Glaxo Wellcome Inc Wasserlösliche Camptothecinderivate
ES2204894T3 (es) * 1991-11-15 2004-05-01 Smithkline Beecham Corporation Composicion que contiene cisplatino y topotecan como agente antitumoral.
CA2125293A1 (en) * 1991-12-10 1993-06-24 Randall Keith Johnson Treatment of colorectal cancer

Also Published As

Publication number Publication date
DK1250926T3 (da) 2008-07-07
DK0678025T3 (da) 1998-10-07
DK0778024T3 (da) 2002-12-23
DE69435084T2 (de) 2009-03-19
DE69431731D1 (de) 2002-12-19
ATE227573T1 (de) 2002-11-15
CA2148822A1 (en) 1994-07-21
EP0778024A1 (de) 1997-06-11
PT1250926E (pt) 2008-06-11
EP1250926A3 (de) 2002-11-20
EP1250926B1 (de) 2008-03-12
DE69435084D1 (de) 2008-04-24
EP1250926A2 (de) 2002-10-23
EP0778024B1 (de) 2002-11-13
DE69409633D1 (de) 1998-05-20
ES2301590T3 (es) 2008-07-01
EP0678025B1 (de) 1998-04-15
ES2114681T3 (es) 1998-06-01
ES2186812T3 (es) 2003-05-16
ATE388706T1 (de) 2008-03-15
CA2148822C (en) 2001-03-27
JPH08505626A (ja) 1996-06-18
EP0678025A1 (de) 1995-10-25
WO1994015604A1 (en) 1994-07-21
DE69409633T2 (de) 1998-08-06
DE69431731T2 (de) 2003-03-13
JP3099128B2 (ja) 2000-10-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee