DK0669129T3 - Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof - Google Patents

Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof

Info

Publication number
DK0669129T3
DK0669129T3 DK95102074T DK95102074T DK0669129T3 DK 0669129 T3 DK0669129 T3 DK 0669129T3 DK 95102074 T DK95102074 T DK 95102074T DK 95102074 T DK95102074 T DK 95102074T DK 0669129 T3 DK0669129 T3 DK 0669129T3
Authority
DK
Denmark
Prior art keywords
contg
polymer
pref
gps
polymers
Prior art date
Application number
DK95102074T
Other languages
English (en)
Inventor
Gunther Dr Penners
Klemens Dr Lustig
Joerg Dr Petersen-Von-Gehr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0669129T3 publication Critical patent/DK0669129T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95102074T 1994-02-28 1995-02-15 Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof DK0669129T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4406424A DE4406424A1 (de) 1994-02-28 1994-02-28 Expandierbare Arzneiformen

Publications (1)

Publication Number Publication Date
DK0669129T3 true DK0669129T3 (da) 2002-02-25

Family

ID=6511366

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95102074T DK0669129T3 (da) 1994-02-28 1995-02-15 Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof

Country Status (10)

Country Link
US (2) US5651985A (da)
EP (1) EP0669129B1 (da)
JP (1) JP3937464B2 (da)
AT (1) ATE207741T1 (da)
CA (1) CA2143500C (da)
DE (2) DE4406424A1 (da)
DK (1) DK0669129T3 (da)
ES (1) ES2166790T3 (da)
PT (1) PT669129E (da)
SI (1) SI0669129T1 (da)

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FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif
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SE9702533D0 (sv) 1997-07-01 1997-07-01 Astra Ab New oral formulation
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US6090411A (en) * 1998-03-09 2000-07-18 Temple University Monolithic tablet for controlled drug release
FR2784583B1 (fr) 1998-10-16 2002-01-25 Synthelabo Composition pharmaceutique a residence gastrique et a liberation controlee
DE19920833A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit quellbaren Polymeren
FR2797185B1 (fr) * 1999-08-06 2001-10-26 Galenix Dev Composition pharmaceutique flottante comprenant une phase active et une phase non active
IL133196A0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
EP1118321A1 (fr) * 2000-01-14 2001-07-25 Ucb, S.A. Compositions pharmaceutiques solides pour la libération contrôlée de substances actives
KR20030025903A (ko) * 2000-02-10 2003-03-29 비피에스아이 홀딩스, 인코포레이션. 아크릴 장용 코팅 조성물
OA12381A (en) * 2000-03-03 2004-09-06 Ranbaxy Lab Ltd Orally administered controlled delivery system foronce daily administration of ciprofloxacin.
DE10014588A1 (de) * 2000-03-27 2001-10-04 Basf Ag Wirkstoffhaltige Schwimmformen enthaltend Polyvinylacetat und Polyvinylpyrrolidon, deren Verwendung und Herstellung
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
EP1245227A1 (en) 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
AU2008255254B2 (en) * 2001-03-31 2010-12-09 Jagotec Ag A pharmaceutical tablet system that floats on gastric fluid for multipulse release of active substance and respective processes of producing same and a cup-shaped envelope of same
AU2002355686B2 (en) * 2001-07-04 2007-11-29 Sun Pharmaceutical Industries Limited Gastric retention controlled drug delivery system
US20040219186A1 (en) * 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
CN1543337A (zh) * 2001-08-16 2004-11-03 ���ո����ɸߵȽ�����ίԱ�������� 可膨胀的胃潴留装置
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
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US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
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US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
CN1630513A (zh) * 2002-02-04 2005-06-22 兰贝克赛实验室有限公司 流体动力平衡的以两相释放的口服药物输递系统
WO2004047768A2 (en) * 2002-11-26 2004-06-10 Seacoast Neuroscience, Inc. Buoyant polymer particles delivering therapeutic agents
TWI355276B (en) * 2003-01-14 2012-01-01 Akira Tsuji Gastrointestinal absorption enhancer mediated by p
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US20050220863A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
WO2006007354A2 (en) * 2004-06-28 2006-01-19 Alza Corporation A drug/polymer complex, preferably ciprofloxacin/hpmc, its method of manufacturing using lyophilization and its use in an osmotic device
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
US9579227B2 (en) 2006-03-29 2017-02-28 Eat Little Inc. Ingestible implement for weight control
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US8426466B2 (en) * 2006-05-22 2013-04-23 Nexus Pharma, Inc. Compositions and methods for enhancing active agent absorption
US8889184B2 (en) * 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
EP2182917B1 (en) * 2007-07-06 2011-07-13 BASF Corporation A gastroretentive composition on the basis of a water-soluble reaction product from a vinyl group- containing precursor
MX2010001071A (es) * 2007-07-27 2010-03-09 Depomed Inc Formas de dosificacion retentivas gastricas pulsatiles.
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
US20110171275A1 (en) * 2007-08-20 2011-07-14 Team Academy Of Pharmaceutical Science Gastroretentive drug delivery system, preparation method and use thereof
CN102202656A (zh) 2008-08-15 2011-09-28 蒂宝制药公司 治疗和预防cns障碍的胃滞留药用组合物
JP2012500230A (ja) 2008-08-18 2012-01-05 北京天衡▲薬▼物研究院 胃内滞留薬物放出システム及びその製造方法と使用
EP2210585A1 (en) 2009-01-16 2010-07-28 Exelgyn SPRM pharmaceutical compositions methods of treatment using them
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US8658631B1 (en) 2011-05-17 2014-02-25 Mallinckrodt Llc Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
WO2013051036A1 (en) 2011-10-03 2013-04-11 Council Of Scientific & Industrial Research Use of pharmaceutical composition for gastroretentive sustained and pulsatile drug delivery system
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
CN105431144A (zh) 2013-06-05 2016-03-23 思康脑侒股份有限公司 阿坎酸制剂、使用阿坎酸制剂的方法以及包含阿坎酸制剂的组合
FR3014692B1 (fr) * 2013-12-18 2016-01-29 Ethypharm Sa Compositions pharmaceutiques orales a retention gastrique.
PL235144B1 (pl) 2014-06-03 2020-06-01 Univ Medyczny Im Piastow Slaskich We Wroclawiu Sposób wytwarzania tabletki flotacyjnej o przedłużonym oddziaływaniu substancji leczniczych z błoną śluzową żołądka oraz kompozycja farmaceutyczna
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
EP3155024B1 (en) 2014-06-11 2020-09-16 Massachusetts Institute Of Technology Residence structures and related methods
AU2016342374B2 (en) * 2015-10-23 2022-08-04 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
US11992552B2 (en) 2015-12-08 2024-05-28 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
CN109890371A (zh) 2016-08-26 2019-06-14 斯瑞尼瓦萨饶·韦帕切杜 组合物及其方法
CN110022861B (zh) 2016-09-30 2024-06-28 林德拉治疗公司 用于金刚烷类药物缓释的胃驻留系统
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WO2023214018A1 (en) * 2022-05-06 2023-11-09 Galenix Innovations Gastro-retentive swellable sustained release composition

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Also Published As

Publication number Publication date
PT669129E (pt) 2002-03-28
ES2166790T3 (es) 2002-05-01
DE4406424A1 (de) 1995-08-31
SI0669129T1 (en) 2002-04-30
ATE207741T1 (de) 2001-11-15
US5651985A (en) 1997-07-29
EP0669129B1 (de) 2001-10-31
EP0669129A3 (de) 1995-11-22
CA2143500C (en) 2007-04-24
CA2143500A1 (en) 1995-08-29
EP0669129A2 (de) 1995-08-30
JPH0840879A (ja) 1996-02-13
JP3937464B2 (ja) 2007-06-27
US6306439B1 (en) 2001-10-23
DE59509765D1 (de) 2001-12-06

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