DK0655996T3 - Substituerede benzylamino-nitrogenholdige, ikke-aromatiske, heterocykliske forbindelser - Google Patents
Substituerede benzylamino-nitrogenholdige, ikke-aromatiske, heterocykliske forbindelserInfo
- Publication number
- DK0655996T3 DK0655996T3 DK93910925T DK93910925T DK0655996T3 DK 0655996 T3 DK0655996 T3 DK 0655996T3 DK 93910925 T DK93910925 T DK 93910925T DK 93910925 T DK93910925 T DK 93910925T DK 0655996 T3 DK0655996 T3 DK 0655996T3
- Authority
- DK
- Denmark
- Prior art keywords
- aromatic heterocyclic
- heterocyclic compounds
- substituted benzylamino
- compounds
- nitrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93239292A | 1992-08-19 | 1992-08-19 | |
PCT/US1993/004063 WO1994004496A1 (en) | 1992-08-19 | 1993-05-05 | Substituted benzylamino nitrogen containing non-aromatic heterocycles |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0655996T3 true DK0655996T3 (da) | 2001-12-27 |
Family
ID=25462237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93910925T DK0655996T3 (da) | 1992-08-19 | 1993-05-05 | Substituerede benzylamino-nitrogenholdige, ikke-aromatiske, heterocykliske forbindelser |
Country Status (17)
Country | Link |
---|---|
US (1) | US5721255A (de) |
EP (2) | EP1114823A3 (de) |
JP (1) | JP2909214B2 (de) |
CN (1) | CN1088917A (de) |
AT (1) | ATE208376T1 (de) |
AU (1) | AU4224993A (de) |
CA (1) | CA2141048C (de) |
DE (1) | DE69331103T2 (de) |
DK (1) | DK0655996T3 (de) |
ES (1) | ES2164072T3 (de) |
FI (1) | FI106552B (de) |
HU (1) | HU9302372D0 (de) |
IL (1) | IL106670A0 (de) |
MX (1) | MX9304996A (de) |
PT (1) | PT655996E (de) |
SI (1) | SI9300443A (de) |
WO (1) | WO1994004496A1 (de) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2087813B1 (es) * | 1993-08-09 | 1997-02-01 | Pfizer | Heterociclos no-aromaticos que contienen nitrogeno bencilamino substituidos. |
GB9317987D0 (en) * | 1993-08-26 | 1993-10-13 | Glaxo Group Ltd | Chemical compounds |
EP1209157A1 (de) * | 1993-09-17 | 2002-05-29 | Pfizer Inc. | Durch Geteroarylamion- und Heteroarylsulfonamido substituierte 3-Benzylaminomethylpiperidine und verwandte Derivate |
EP0653208A3 (de) * | 1993-11-17 | 1995-10-11 | Pfizer | Substanz P Antagonisten zur Behandlung oder Verhütung des sonnenbrandes. |
EP0659409A3 (de) * | 1993-11-23 | 1995-08-09 | Pfizer | Substanz P Antagonisten zur Hemmung der Angiogenese. |
EP0655246A1 (de) * | 1993-11-30 | 1995-05-31 | Pfizer Inc. | Substanz P Antagonisten zur Behandlung von durch Helicobacter Pylori oder andere spirale Urease-positive Gram-negative Bakterien verursachten Krankheiten |
IL116249A (en) * | 1994-12-12 | 2003-07-06 | Pfizer | Nk-1 receptor antagonists for the treatment of neuronal damage and stroke |
TW458774B (en) | 1995-10-20 | 2001-10-11 | Pfizer | Antiemetic pharmaceutical compositions |
GB9525296D0 (en) * | 1995-12-11 | 1996-02-07 | Merck Sharp & Dohme | Therapeutic agents |
DE69623580T2 (de) * | 1995-12-21 | 2003-01-09 | Pfizer | 3-((5-Substituierte Benzyl)Amino)-2-Phenylpiperidine als Substance-P-Antagonisten |
MX9706196A (es) * | 1996-08-14 | 1998-02-28 | Pfizer | Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p. |
CA2291734A1 (en) * | 1997-06-27 | 1999-01-07 | Merck Sharp & Dohme Limited | Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents |
AU2001288972A1 (en) | 2000-09-11 | 2002-03-26 | Sepracor, Inc. | Antipsychotic sulfonamide-heterocycles, and methods of use thereof |
AU2001292320A1 (en) * | 2000-10-02 | 2002-04-15 | Tanabe Seiyaku Co., Ltd. | Benzylamine compound, process for producing the same, and intermediate therefor |
DE10155075A1 (de) | 2001-11-09 | 2003-05-22 | Merck Patent Gmbh | Cyclische Sulfonamide |
US6861526B2 (en) | 2002-10-16 | 2005-03-01 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
US20050136487A1 (en) * | 2003-10-27 | 2005-06-23 | Meyer Donald W. | Transmissible spongiform encephalopathy detection in cervids, sheep and goats |
MX2007000428A (es) | 2004-07-15 | 2008-03-05 | Amr Technology Inc | Tetrahidroisoquinolinas sustituidas con arilo y heteroarilo y uso de las mismas para bloquear la captacion de norepinefrina, dopamina y serotonina. |
ATE550019T1 (de) | 2005-05-17 | 2012-04-15 | Merck Sharp & Dohme | Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs |
EP1905777B2 (de) * | 2005-07-04 | 2018-06-27 | Zannan Scitech Co., Ltd. | Rutheniumkomplexligand, rutheniumkomplex, geträgerter rutheniumkomplexkatalysator und herstellungsverfahren und anwendung davon |
CA2615403C (en) | 2005-07-15 | 2015-06-16 | Amr Technology, Inc. | Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
AU2006297443B2 (en) | 2005-09-29 | 2010-08-12 | Merck Sharp & Dohme Corp. | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
GB0603041D0 (en) | 2006-02-15 | 2006-03-29 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
CA2664113C (en) | 2006-09-22 | 2013-05-28 | Merck & Co., Inc. | Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer |
US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
EP2109608B1 (de) | 2007-01-10 | 2011-03-23 | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. | Amidsubstituierte indazole als poly-(adp-ribose)-polymerase (parp)-hemmer |
US8106086B2 (en) | 2007-04-02 | 2012-01-31 | Msd K.K. | Indoledione derivative |
JP5501227B2 (ja) | 2007-06-27 | 2014-05-21 | メルク・シャープ・アンド・ドーム・コーポレーション | ヒストンデアセチラーゼ阻害剤としての4−カルボキシベンジルアミノ誘導体 |
AU2009222122A1 (en) | 2008-03-03 | 2009-09-11 | Tiger Pharmatech | Tyrosine kinase inhibitors |
US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
UA105182C2 (ru) | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность |
GB0815782D0 (en) * | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
GB0815781D0 (en) * | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
GB0815784D0 (en) * | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
TW201026675A (en) * | 2008-10-09 | 2010-07-16 | Anadys Pharmaceuticals Inc | 5,6-dihydro-1H-pyridin-2-one compounds |
EP2413932A4 (de) | 2009-04-01 | 2012-09-19 | Merck Sharp & Dohme | Hemmer der akt-aktivität |
ES2662072T3 (es) | 2009-05-12 | 2018-04-05 | Albany Molecular Research, Inc. | 7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y uso de la misma |
KR20120034644A (ko) | 2009-05-12 | 2012-04-12 | 알바니 몰레큘라 리써치, 인크. | 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도 |
EP2429293B1 (de) | 2009-05-12 | 2014-10-29 | Bristol-Myers Squibb Company | KRISTALLINE FORMEN VON (S)-7-([1,2,4]TRIAZOL[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLORPHENYL)-1,2,3,4-TETRAHYDROISOCHINOLIN UND IHRE VERWENDUNG |
KR101485645B1 (ko) | 2009-10-14 | 2015-01-22 | 머크 샤프 앤드 돔 코포레이션 | p53 활성을 증가시키는 치환된 피페리딘 및 그의 용도 |
WO2011163330A1 (en) | 2010-06-24 | 2011-12-29 | Merck Sharp & Dohme Corp. | Novel heterocyclic compounds as erk inhibitors |
CN107090456B (zh) | 2010-08-02 | 2022-01-18 | 瑟纳治疗公司 | 使用短干扰核酸的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1基因表达的抑制 |
HUE044815T2 (hu) | 2010-08-17 | 2019-11-28 | Sirna Therapeutics Inc | Hepatitisz B vírus (HBV) génexpressziójának RNS-interferencia közvetített gátlása, rövid interferáló nukleinsav (SINS) alkalmazásával |
US8883801B2 (en) | 2010-08-23 | 2014-11-11 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors |
WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
US9242981B2 (en) | 2010-09-16 | 2016-01-26 | Merck Sharp & Dohme Corp. | Fused pyrazole derivatives as novel ERK inhibitors |
WO2012058210A1 (en) | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) |
US9351965B2 (en) | 2010-12-21 | 2016-05-31 | Merck Sharp & Dohme Corp. | Indazole derivatives useful as ERK inhibitors |
CN103732592A (zh) | 2011-04-21 | 2014-04-16 | 默沙东公司 | 胰岛素样生长因子-1受体抑制剂 |
US9023865B2 (en) | 2011-10-27 | 2015-05-05 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
EP3919620A1 (de) | 2012-05-02 | 2021-12-08 | Sirna Therapeutics, Inc. | Zusammensetzungen mit kurzer interferierender nukleinsäure (sina) |
CA2882950A1 (en) | 2012-09-28 | 2014-04-03 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
EP2919788A4 (de) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | Verfahren und zusammensetzungen zur behandlung von schizophrenie |
LT2925888T (lt) | 2012-11-28 | 2018-01-10 | Merck Sharp & Dohme Corp. | Vėžio gydymo kompozicijos ir būdai |
BR112015013611A2 (pt) | 2012-12-20 | 2017-11-14 | Merck Sharp & Dohme | composto, e, composição farmacêutica |
WO2014120748A1 (en) | 2013-01-30 | 2014-08-07 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as hdm2 inhibitors |
US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
US20170140680A1 (en) * | 2015-11-12 | 2017-05-18 | J. J. Keller & Associates, Inc. | Electronic placard |
US10947234B2 (en) | 2017-11-08 | 2021-03-16 | Merck Sharp & Dohme Corp. | PRMT5 inhibitors |
WO2020019247A1 (en) | 2018-07-26 | 2020-01-30 | Xw Laboratories, Inc. | Compounds as neurokinin-1 receptor antagonists and uses thereof |
US20210277009A1 (en) | 2018-08-07 | 2021-09-09 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
US20210309688A1 (en) | 2018-08-07 | 2021-10-07 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
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CS174885B2 (de) * | 1972-06-01 | 1977-04-29 | ||
GB1574418A (en) * | 1976-11-16 | 1980-09-03 | Anphar Sa | Piperidine derivatives |
MX18467A (es) * | 1988-11-23 | 1993-07-01 | Pfizer | Agentes terapeuticos de quinuclidinas |
US5232929A (en) * | 1990-11-28 | 1993-08-03 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use |
DK0532527T3 (da) * | 1990-06-01 | 1995-01-02 | Pfizer | 3-amino-2-arylquinuclidiner, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse |
CA2086434C (en) * | 1990-07-23 | 1998-09-22 | John A. Lowe, Iii | Quinuclidine derivatives |
CA2089736A1 (en) * | 1990-09-28 | 1992-03-29 | Manoj C. Desai | Fused ring analogs of nitrogen containing nonaromatic heterocycles |
WO1992015585A1 (en) * | 1991-03-01 | 1992-09-17 | Pfizer Inc. | 1-azabicyclo[3.2.2]nonan-3-amine derivatives |
RU2105001C1 (ru) * | 1991-03-26 | 1998-02-20 | Пфайзер Инк. | Способ получения замещенных 3-аминопиперидинов |
ATE211743T1 (de) * | 1991-05-22 | 2002-01-15 | Pfizer | Substituierte 3-aminochinuclidine |
DE9290063U1 (de) * | 1991-05-31 | 1994-02-24 | Pfizer | Chinuclidin-Derivate |
CA2109613C (en) * | 1991-06-20 | 1996-11-19 | John Adams Lowe Iii | Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles |
TW202432B (de) * | 1991-06-21 | 1993-03-21 | Pfizer | |
EP0536817A1 (de) * | 1991-07-05 | 1993-04-14 | MERCK SHARP & DOHME LTD. | Azabicyclische Verbindungen als Tachykinin-Antagonisten |
DE69232588T2 (de) * | 1991-09-26 | 2002-08-22 | Pfizer | Kondensierte trizyklische, stickstoffenthaltende Verbindungen als Substanz P Rezeptor Antagonisten |
ATE161821T1 (de) * | 1991-11-12 | 1998-01-15 | Pfizer | Azyklische ethylendiaminderivate als 'substance p rezeptor' antagonisten |
-
1993
- 1993-05-05 AT AT93910925T patent/ATE208376T1/de not_active IP Right Cessation
- 1993-05-05 EP EP01108881A patent/EP1114823A3/de not_active Withdrawn
- 1993-05-05 PT PT93910925T patent/PT655996E/pt unknown
- 1993-05-05 JP JP6506227A patent/JP2909214B2/ja not_active Expired - Fee Related
- 1993-05-05 CA CA002141048A patent/CA2141048C/en not_active Expired - Fee Related
- 1993-05-05 ES ES93910925T patent/ES2164072T3/es not_active Expired - Lifetime
- 1993-05-05 AU AU42249/93A patent/AU4224993A/en not_active Abandoned
- 1993-05-05 DE DE69331103T patent/DE69331103T2/de not_active Expired - Fee Related
- 1993-05-05 DK DK93910925T patent/DK0655996T3/da active
- 1993-05-05 US US08/387,765 patent/US5721255A/en not_active Expired - Fee Related
- 1993-05-05 EP EP93910925A patent/EP0655996B1/de not_active Expired - Lifetime
- 1993-05-05 WO PCT/US1993/004063 patent/WO1994004496A1/en active IP Right Grant
- 1993-08-12 IL IL106670A patent/IL106670A0/xx unknown
- 1993-08-17 MX MX9304996A patent/MX9304996A/es unknown
- 1993-08-18 HU HU9302372A patent/HU9302372D0/hu unknown
- 1993-08-18 FI FI933641A patent/FI106552B/fi not_active IP Right Cessation
- 1993-08-18 CN CN93109599A patent/CN1088917A/zh active Pending
- 1993-08-23 SI SI9300443A patent/SI9300443A/sl unknown
Also Published As
Publication number | Publication date |
---|---|
WO1994004496A1 (en) | 1994-03-03 |
CN1088917A (zh) | 1994-07-06 |
CA2141048A1 (en) | 1994-03-03 |
US5721255A (en) | 1998-02-24 |
ATE208376T1 (de) | 2001-11-15 |
EP1114823A2 (de) | 2001-07-11 |
FI933641A (fi) | 1994-02-20 |
DE69331103T2 (de) | 2002-03-14 |
EP0655996A1 (de) | 1995-06-07 |
AU4224993A (en) | 1994-03-15 |
HU9302372D0 (en) | 1993-10-28 |
IL106670A0 (en) | 1993-12-08 |
EP1114823A3 (de) | 2001-07-18 |
PT655996E (pt) | 2002-04-29 |
SI9300443A (en) | 1994-06-30 |
JPH07508755A (ja) | 1995-09-28 |
MX9304996A (es) | 1994-05-31 |
CA2141048C (en) | 2003-03-18 |
EP0655996B1 (de) | 2001-11-07 |
ES2164072T3 (es) | 2002-02-16 |
DE69331103D1 (de) | 2001-12-13 |
FI106552B (fi) | 2001-02-28 |
FI933641A0 (fi) | 1993-08-18 |
JP2909214B2 (ja) | 1999-06-23 |
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