DK0652752T3 - Vanddispergerbare tabletter - Google Patents
Vanddispergerbare tabletterInfo
- Publication number
- DK0652752T3 DK0652752T3 DK93917926T DK93917926T DK0652752T3 DK 0652752 T3 DK0652752 T3 DK 0652752T3 DK 93917926 T DK93917926 T DK 93917926T DK 93917926 T DK93917926 T DK 93917926T DK 0652752 T3 DK0652752 T3 DK 0652752T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- date
- sec
- disintegrating agent
- water dispersible
- Prior art date
Links
- 239000004565 water dispersible tablet Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- RRMBHRAGONDLTM-UHFFFAOYSA-N 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)-1h-pyrimidin-2-amine Chemical compound C1CN(C)CCN1C1(N)N=CC(C=2C(=C(Cl)C=C(Cl)C=2)Cl)=CN1 RRMBHRAGONDLTM-UHFFFAOYSA-N 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- -1 Alzheimer's disease Chemical compound 0.000 abstract 1
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
- 239000002858 neurotransmitter agent Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- General Preparation And Processing Of Foods (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929215908A GB9215908D0 (en) | 1992-07-27 | 1992-07-27 | Water dispersible tablets |
PCT/GB1993/001586 WO1994002147A1 (en) | 1992-07-27 | 1993-07-27 | Water-dispersible tablets |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0652752T3 true DK0652752T3 (da) | 2000-03-20 |
Family
ID=10719356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93917926T DK0652752T3 (da) | 1992-07-27 | 1993-07-27 | Vanddispergerbare tabletter |
Country Status (14)
Country | Link |
---|---|
US (1) | US5698221A (da) |
EP (1) | EP0652752B1 (da) |
JP (1) | JPH07509463A (da) |
AT (1) | ATE184486T1 (da) |
AU (1) | AU4717193A (da) |
DE (1) | DE69326470T2 (da) |
DK (1) | DK0652752T3 (da) |
ES (1) | ES2137267T3 (da) |
GB (1) | GB9215908D0 (da) |
GR (1) | GR3031679T3 (da) |
IL (1) | IL106492A0 (da) |
MX (1) | MX9304502A (da) |
WO (1) | WO1994002147A1 (da) |
ZA (1) | ZA935381B (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL145688A0 (en) * | 1999-03-29 | 2002-06-30 | American Home Prod | Coating system |
US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
ATE319447T1 (de) * | 1999-08-16 | 2006-03-15 | Revaax Pharmaceuticals Llc | Pharmazeutische zubereitungen die clavulansäure oder derivate enthalten zur behandlund von neurologischen störungen |
GB0223978D0 (en) * | 2002-10-15 | 2002-11-20 | Novartis Ag | Organic compound |
ES2335008T3 (es) * | 2003-04-24 | 2010-03-18 | Jagotec Ag | Comprimido con nucleo coloreado. |
JP4999329B2 (ja) | 2003-12-01 | 2012-08-15 | 武田薬品工業株式会社 | 固形製剤の印刷前処理方法 |
GB0408078D0 (en) * | 2004-04-08 | 2004-05-12 | Novartis Ag | Organic compounds |
EP1906937B1 (en) | 2005-07-22 | 2016-10-19 | Rubicon Research Pvt Ltd. | Novel dispersible tablet composition |
KR20080056225A (ko) * | 2005-10-19 | 2008-06-20 | 노파르티스 아게 | 데페라시록스를 포함하는 분산성 정제 |
MY149863A (en) | 2006-08-03 | 2013-10-31 | Nitec Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid disease |
US20100255099A1 (en) * | 2007-10-26 | 2010-10-07 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB777516A (en) * | 1955-04-14 | 1957-06-26 | Griffiths Hughes Ltd E | Improvements in or relating to the production of tablets by pressure |
GB837451A (en) * | 1956-02-20 | 1960-06-15 | Arner Co Inc | Sustained release therapeutic composition and process of preparing same |
US3432593A (en) * | 1963-09-18 | 1969-03-11 | Key Pharm Inc | Delayed and sustained release type pharmaceutical preparation |
US3427379A (en) * | 1966-01-13 | 1969-02-11 | Hoffmann La Roche | Dextromethorphan and benzyl alcohol hard candy lozenges free from opaqueness and/or tiny entrapped air bubbles |
NL6814269A (da) * | 1967-10-13 | 1969-04-15 | ||
DE2016622A1 (en) * | 1970-04-08 | 1971-10-21 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Anthelmintic benzimidazole deriv |
FR2096292A5 (da) * | 1970-06-15 | 1972-02-11 | Sumitomo Chemical Co | |
US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
FR2183546B1 (da) * | 1972-05-10 | 1975-06-20 | Servier Lab | |
DE2251249A1 (de) * | 1972-10-19 | 1974-05-02 | Hoechst Ag | Verfahren zur herstellung von penicillin-verbindungen enthaltenden tabletten |
US4209513A (en) * | 1974-02-14 | 1980-06-24 | Burroughs Wellcome Co. | Tablet formulation |
DE2416903A1 (de) * | 1974-04-06 | 1975-10-09 | Bayer Ag | Verwendung von schmelzverspruehtem kugelfoermigem phenacetingranulat zur herstellung von tabletten im direkttablettierverfahren |
JPS5154918A (en) * | 1974-10-08 | 1976-05-14 | Nippon Kayaku Kk | Jozaino seizoho |
US4086335A (en) * | 1975-10-29 | 1978-04-25 | Bruscato Frank N | Pharmaceutical tablets containing chitin as a disintegrant |
DE2552967A1 (de) * | 1975-11-26 | 1977-06-08 | Bayer Ag | Fungizide mittel |
GB1548022A (en) * | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
AU508480B2 (en) * | 1977-04-13 | 1980-03-20 | Asahi Kasei Kogyo Kabushiki Kaisha | Microcrystalline cellulose excipient and pharmaceutical composition containing thesame |
CA1097233A (en) * | 1977-07-20 | 1981-03-10 | George K. E. Gregory | Packages |
DE2849494A1 (de) * | 1978-11-15 | 1980-05-29 | Voss Gunter M | Verfahren zur herstellung von arzneimittel-formlingen |
HU182086B (en) * | 1979-06-01 | 1983-12-28 | Wellcome Found | Process for preparing new 1,2,4-triazine derivatives |
US4251518A (en) * | 1979-07-03 | 1981-02-17 | Ralston Purina Company | Method of preparing readily disintegrable pharmaceutical compositions |
US4304773A (en) * | 1980-06-26 | 1981-12-08 | E. R. Squibb & Sons, Inc. | Novel bendroflumethiazide formulations and method |
US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
HU189534B (en) * | 1981-09-09 | 1986-07-28 | Chinoin Rt.,Hu | Process for producing new tablets containing cyclodextrin polymer as desintegrator |
DE3142826A1 (de) * | 1981-10-29 | 1983-05-11 | Rütgerswerke AG, 6000 Frankfurt | Verfahren zur herstellung einer hochreaktiven pechfraktion und deren verwendung |
US4517179A (en) * | 1983-04-29 | 1985-05-14 | Pennwalt Corporation | Rapid dissolving, uniform drug compositions and their preparation |
US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
US4661521A (en) * | 1984-04-30 | 1987-04-28 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
DE3505433A1 (de) * | 1985-02-16 | 1986-08-21 | Basf Ag, 6700 Ludwigshafen | Direkttablettierhilfsmittel |
US4631305A (en) * | 1985-03-22 | 1986-12-23 | The Upjohn Company | Polymeric material as a disintegrant in a compressed tablet |
EP0199855A1 (en) * | 1985-05-02 | 1986-11-05 | Gist-Brocades N.V. | Tablets comprising tromethoprim and a sulfonamide |
WO1987001936A1 (en) * | 1985-09-25 | 1987-04-09 | Gerhard Gergely | Desintegration tablet and process for its manufacture |
US4781925A (en) * | 1986-03-06 | 1988-11-01 | American Home Products Corporation | Calcium supplement compressed tablets |
KR880701098A (ko) * | 1986-04-01 | 1988-07-25 | 로버어트 에이 아미테이지 | 메틸프레드니솔론/소디움 카르복시메틸 전분 정제 조성물 |
GB8613183D0 (en) * | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
DE3635864A1 (de) * | 1986-06-26 | 1988-05-05 | Gerhard Gergely | Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung |
US4757090A (en) * | 1986-07-14 | 1988-07-12 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
KR960001372B1 (ko) * | 1986-09-24 | 1996-01-26 | 예일 유니버시티 | 레트로비루스로 감염된 환자의 치료에 사용되는 2',3'-디디옥시사이티딘-2'-엔(2',3'-디디옥시-2',3'-디디하이드로사이티딘)의 항생물질 |
US4771077A (en) * | 1986-10-21 | 1988-09-13 | American Home Products Corporation (Del.) | Spray dried acetaminophen |
GB8628359D0 (en) * | 1986-11-27 | 1986-12-31 | Zyma Sa | Galenical formulation |
DE3887179T2 (de) * | 1987-03-02 | 1994-06-16 | Brocades Pharma Bv | Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. |
ATE73328T1 (de) * | 1987-05-08 | 1992-03-15 | Smith Kline French Lab | Pharmazeutische zusammensetzungen. |
US4904477A (en) * | 1987-07-08 | 1990-02-27 | American Home Products Corporation | Spray dried ibuprofen compositions |
EP0300111B1 (en) * | 1987-07-22 | 1991-10-16 | Farvalsa AG | A moisture stable solid valproic acid formulation and a method of preparing the same |
DE3806633A1 (de) * | 1987-09-01 | 1989-03-09 | Bayer Ag | Antivirales mittel |
US4837031A (en) * | 1987-09-17 | 1989-06-06 | Mallinckrodt, Inc. | Compositions containing ibuprofen |
US4999200A (en) * | 1987-12-09 | 1991-03-12 | Marion Laboratories | Psyllium tablet composition, method of manufacture and method of use |
ATE108996T1 (de) * | 1988-02-25 | 1994-08-15 | Brocades Pharma Bv | Verfahren zur herstellung eines pharmazeutischen granulats. |
US4910023A (en) * | 1988-06-09 | 1990-03-20 | Warner-Lambert Company | Drug in combination with flavor masking agent and method for making same |
YU120988A (en) * | 1988-06-23 | 1990-06-30 | Lek Tovarna Farmacevtskih | Process for preparing new dispersion pills of cimetidine |
IT1226549B (it) * | 1988-07-12 | 1991-01-24 | Resa Farma | Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose. |
YU183988A (en) * | 1988-09-30 | 1990-08-31 | Lek Tovarna Farmacevtskih | Process for preparing dispersion pills of dihydroergotoxine |
US4965072A (en) * | 1988-11-03 | 1990-10-23 | Miles Inc. | Granulating composition and method |
US5073377A (en) * | 1988-11-03 | 1991-12-17 | Miles Inc. | Method of preparing oral dosage forms with a granulating composition |
FI895821A0 (fi) * | 1988-12-07 | 1989-12-05 | Wellcome Found | Farmaceutiskt aktiva cns foereningar. |
US4925676A (en) * | 1989-02-02 | 1990-05-15 | Warner-Lambert Company | Extended release gemfibrozil composition |
US4927639A (en) * | 1989-02-02 | 1990-05-22 | Warner-Lambert Company | Modified release gemfibrozil composition |
DE59006174D1 (de) * | 1989-04-07 | 1994-07-28 | Ciba Geigy Ag | Pestizide Wirkstoffkonzentrate und ihre Herstellung. |
US4970078A (en) * | 1989-05-25 | 1990-11-13 | Aqualon Company | Crosslinked carboxymethyguar tablet disintegrant |
US5260304A (en) * | 1989-09-07 | 1993-11-09 | Gerhard Gergely | Pharmaceutical preparation binding with gastric acid |
US5037658A (en) * | 1989-09-14 | 1991-08-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Direct dry compressible acetaminophen composition |
US5064656A (en) * | 1989-11-14 | 1991-11-12 | Dr. Gergely & Co. | Uncoated pharmaceutical reaction tablet |
GB9012316D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
GB9012311D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
US5087454A (en) * | 1990-07-30 | 1992-02-11 | American Home Products Corporation | Ibuprofen tablet |
GB9025372D0 (en) * | 1990-11-22 | 1991-01-09 | Nat Res Dev | Pharmaceutical dosage forms |
-
1992
- 1992-07-27 GB GB929215908A patent/GB9215908D0/en active Pending
-
1993
- 1993-07-26 MX MX9304502A patent/MX9304502A/es unknown
- 1993-07-26 ZA ZA935381A patent/ZA935381B/xx unknown
- 1993-07-27 JP JP6504326A patent/JPH07509463A/ja active Pending
- 1993-07-27 ES ES93917926T patent/ES2137267T3/es not_active Expired - Lifetime
- 1993-07-27 DE DE69326470T patent/DE69326470T2/de not_active Expired - Fee Related
- 1993-07-27 AT AT93917926T patent/ATE184486T1/de not_active IP Right Cessation
- 1993-07-27 AU AU47171/93A patent/AU4717193A/en not_active Abandoned
- 1993-07-27 US US08/374,728 patent/US5698221A/en not_active Expired - Fee Related
- 1993-07-27 IL IL106492A patent/IL106492A0/xx unknown
- 1993-07-27 EP EP93917926A patent/EP0652752B1/en not_active Expired - Lifetime
- 1993-07-27 DK DK93917926T patent/DK0652752T3/da active
- 1993-07-27 WO PCT/GB1993/001586 patent/WO1994002147A1/en active IP Right Grant
-
1999
- 1999-10-27 GR GR990402769T patent/GR3031679T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
MX9304502A (es) | 1994-06-30 |
ES2137267T3 (es) | 1999-12-16 |
ATE184486T1 (de) | 1999-10-15 |
GB9215908D0 (en) | 1992-09-09 |
WO1994002147A1 (en) | 1994-02-03 |
DE69326470D1 (de) | 1999-10-21 |
US5698221A (en) | 1997-12-16 |
DE69326470T2 (de) | 2000-01-13 |
GR3031679T3 (en) | 2000-02-29 |
EP0652752B1 (en) | 1999-09-15 |
ZA935381B (en) | 1995-01-26 |
IL106492A0 (en) | 1993-11-15 |
AU4717193A (en) | 1994-02-14 |
EP0652752A1 (en) | 1995-05-17 |
JPH07509463A (ja) | 1995-10-19 |
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