DK0650410T3 - Fremgangsmåde til fremstilling af lægemiddelformuleringer - Google Patents

Fremgangsmåde til fremstilling af lægemiddelformuleringer

Info

Publication number
DK0650410T3
DK0650410T3 DK93914852.4T DK93914852T DK0650410T3 DK 0650410 T3 DK0650410 T3 DK 0650410T3 DK 93914852 T DK93914852 T DK 93914852T DK 0650410 T3 DK0650410 T3 DK 0650410T3
Authority
DK
Denmark
Prior art keywords
mold
drug formulations
preparing drug
disclosed
longitudinal axis
Prior art date
Application number
DK93914852.4T
Other languages
Danish (da)
English (en)
Inventor
David John Livesley
Ian Michael Daines Gaylor
Original Assignee
Fisons Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Plc filed Critical Fisons Plc
Application granted granted Critical
Publication of DK0650410T3 publication Critical patent/DK0650410T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/02—Dies; Inserts therefor; Mounting thereof; Moulds
    • B30B15/022—Moulds for compacting material in powder, granular of pasta form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/007—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a plurality of pressing members working in different directions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A61M2202/066—Powder made from a compacted product by abrading
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S425/00—Plastic article or earthenware shaping or treating: apparatus
    • Y10S425/014—Expansible and collapsible
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S425/00—Plastic article or earthenware shaping or treating: apparatus
    • Y10S425/044—Rubber mold

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Saccharide Compounds (AREA)
DK93914852.4T 1992-06-30 1993-06-30 Fremgangsmåde til fremstilling af lægemiddelformuleringer DK0650410T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929213874A GB9213874D0 (en) 1992-06-30 1992-06-30 Process to novel medicament form

Publications (1)

Publication Number Publication Date
DK0650410T3 true DK0650410T3 (da) 1998-05-25

Family

ID=10717946

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93914852.4T DK0650410T3 (da) 1992-06-30 1993-06-30 Fremgangsmåde til fremstilling af lægemiddelformuleringer

Country Status (11)

Country Link
US (1) US5976436A (el)
EP (1) EP0650410B1 (el)
JP (1) JP3477201B2 (el)
AT (1) ATE160725T1 (el)
CA (1) CA2137826C (el)
DE (1) DE69315578T2 (el)
DK (1) DK0650410T3 (el)
ES (1) ES2110098T3 (el)
GB (1) GB9213874D0 (el)
GR (1) GR3026059T3 (el)
WO (1) WO1994000291A1 (el)

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DE4436854A1 (de) * 1994-10-15 1996-04-18 Ggu Gesundheits Umweltforsch Arzneistoff-Vorrat zur mechanischen Freisetzung von lungengängigen Wirkstoff-Aerosolen für die inhalative Applikation von Arzneistoffen
US5676967A (en) * 1995-04-18 1997-10-14 Brennen Medical, Inc. Mesh matrix wound dressing
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
EP1280520B2 (en) 2000-05-10 2018-03-21 Novartis AG Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
RU2003136260A (ru) * 2001-05-17 2005-05-20 Рейдер Компаниз (Us) Молотковая дробилка
US7134623B2 (en) * 2001-05-17 2006-11-14 Rader Companies Hammermill
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
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US7879833B2 (en) 2002-12-12 2011-02-01 Nycomed Gmbh Combination medicament
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EP1670482B2 (en) 2003-09-16 2022-06-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
DE102004026969A1 (de) * 2004-06-02 2005-12-29 Sms Meer Gmbh Vorrichtung zum Herstellen eines Formteils aus Pulver
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
DK1937219T3 (en) 2005-09-14 2016-02-15 Mannkind Corp A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles
US20070197486A1 (en) * 2005-12-20 2007-08-23 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids
US20070178049A1 (en) * 2005-12-20 2007-08-02 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070185066A1 (en) * 2005-12-20 2007-08-09 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070160542A1 (en) * 2005-12-20 2007-07-12 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070249572A1 (en) * 2005-12-20 2007-10-25 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
JP2009526858A (ja) * 2006-02-15 2009-07-23 ティカ レーケメデル アーベー コルチコステロイド溶液を製造する方法
IN2015DN00888A (el) 2006-02-22 2015-07-10 Mannkind Corp
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
KR20110091505A (ko) * 2008-10-14 2011-08-11 악티바에로 게엠베하 Ｃｏｐｄ 및 기타 폐질환의 치료 방법
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
AR079451A1 (es) 2009-12-18 2012-01-25 Nycomed Gmbh Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
JP2014519519A (ja) 2011-06-15 2014-08-14 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規３，４，４ａ，１０ｂ−テトラヒドロ−１Ｈ−チオピラノ［４，３−ｃ］イソキノリン化合物
BR112013031791A2 (pt) 2011-06-17 2017-01-31 Takeda Gmbh derivados de ftalazinona-pirrolopirimidinacarboxamida
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CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2018069210A1 (en) 2016-10-10 2018-04-19 Takeda Gmbh Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4
EP3892401A1 (en) * 2020-04-08 2021-10-13 Walter Ag Press tool and method for forming a cutting insert green body having a through hole

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US950567A (en) * 1908-11-30 1910-03-01 Granville Kesling Pipe and tile mold.
US2312381A (en) * 1940-10-24 1943-03-02 Frank J Bickenheuser Medicinal tablet
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
GB881701A (en) * 1959-09-11 1961-11-08 Ici Ltd Production of hollow articles from polytetrafluoroethylene
FR1346567A (fr) * 1962-12-26 1963-12-20 Asea Ab Appareil à haute pression, notamment pour la transformation du graphite en diamant
US3561079A (en) * 1968-03-11 1971-02-09 Robinson Clay Product Co The Apparatus for pressing of clay pipe using an elastomeric mandrel
US3583200A (en) * 1969-05-19 1971-06-08 Grotnes Machine Works Inc Expanding head and improved seal therefor
CA1058814A (en) * 1973-11-13 1979-07-24 Sumitomo Electric Industries, Ltd. Method for producing a tubular multi-layered porous barrier
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
CA2007683A1 (en) * 1989-02-03 1990-08-03 James C. Danly, Sr. Composite and self-lubricating bushing and method for making same
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
DE69012458T3 (de) * 1989-05-31 2000-01-20 Fisons Plc, Ipswich Medikament und Inhalationsvorrichtung dafür.

Also Published As

Publication number Publication date
US5976436A (en) 1999-11-02
DE69315578T2 (de) 1998-04-02
ES2110098T3 (es) 1998-02-01
EP0650410B1 (en) 1997-12-03
JPH07508194A (ja) 1995-09-14
CA2137826A1 (en) 1994-01-06
CA2137826C (en) 2005-01-25
GR3026059T3 (en) 1998-05-29
WO1994000291A1 (en) 1994-01-06
JP3477201B2 (ja) 2003-12-10
EP0650410A1 (en) 1995-05-03
GB9213874D0 (en) 1992-08-12
ATE160725T1 (de) 1997-12-15
DE69315578D1 (de) 1998-01-15

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