ES8103972A1 - Un procedimiento para preparar una composicion farmaceutica que contiene fumarato de benciclano y ciclodextrina - Google Patents

Un procedimiento para preparar una composicion farmaceutica que contiene fumarato de benciclano y ciclodextrina

Info

Publication number
ES8103972A1
ES8103972A1 ES490848A ES490848A ES8103972A1 ES 8103972 A1 ES8103972 A1 ES 8103972A1 ES 490848 A ES490848 A ES 490848A ES 490848 A ES490848 A ES 490848A ES 8103972 A1 ES8103972 A1 ES 8103972A1
Authority
ES
Spain
Prior art keywords
bencyclane fumarate
preparation
bencyclane
fumarate
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490848A
Other languages
English (en)
Other versions
ES490848A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5216479A external-priority patent/JPS55143911A/ja
Priority claimed from JP15715179A external-priority patent/JPS5679650A/ja
Priority claimed from JP920180A external-priority patent/JPS55143912A/ja
Priority claimed from JP1704280A external-priority patent/JPS56113712A/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of ES490848A0 publication Critical patent/ES490848A0/es
Publication of ES8103972A1 publication Critical patent/ES8103972A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA COMPOSICION FARMACEUTICA QUE CONTIENE FUMARATO DE BENCICLANO Y CICLODEXTRINA. SE OBTIENE MEZCLANDO FUMARATO DE BENCICLANO Y CICLODEXTRINA EN UNA RELACION MOLAR DE 1:5 Y 5:1, CON LO CUAL SE CONVIERTE TODO O PARTE EN UN COMPUESTO DE INCLUSION. LA MEZCLA SE LLEVA A CABO AMASANDO LOS COMPONENTES DURANTE 0,1-12 HORAS, JUNTO CON AGUA O UNA MEZCLA DE AGUA O UNO O MAS DISOLVENTES ORGANICOS MISCIBLES CON AGUA. LA MEZCLA RESULTANTE SE SECA MEDIANTE LIOFILIZACION, SECADO POR PULVERIZACION O AL VACIO. LOS DISOLVENTES ORGANICOS EMPLEADOS PUEDEN SER METANOL, ETANOL, ACETONA, ALCOHOL N-PROPILO O ALCOHOL ISOPROPILICO.
ES490848A 1979-04-26 1980-04-24 Un procedimiento para preparar una composicion farmaceutica que contiene fumarato de benciclano y ciclodextrina Expired ES8103972A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5216479A JPS55143911A (en) 1979-04-26 1979-04-26 Bencyclane fumarate preparation
JP15715179A JPS5679650A (en) 1979-12-04 1979-12-04 Bencyclane fumarate clathrate compound
JP920180A JPS55143912A (en) 1980-01-28 1980-01-28 Useful preparation comprising bencyclane fumarate
JP1704280A JPS56113712A (en) 1980-02-13 1980-02-13 Production of pharmaceutical preparation of bencyclane fumarate

Publications (2)

Publication Number Publication Date
ES490848A0 ES490848A0 (es) 1981-04-16
ES8103972A1 true ES8103972A1 (es) 1981-04-16

Family

ID=27455119

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490848A Expired ES8103972A1 (es) 1979-04-26 1980-04-24 Un procedimiento para preparar una composicion farmaceutica que contiene fumarato de benciclano y ciclodextrina

Country Status (7)

Country Link
US (1) US4352793A (es)
EP (1) EP0018773B1 (es)
CA (1) CA1146545A (es)
DE (1) DE3063842D1 (es)
ES (1) ES8103972A1 (es)
HU (1) HU183129B (es)
MX (1) MX5999E (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5830032B2 (ja) * 1981-02-18 1983-06-27 呉羽化学工業株式会社 ビフイダス菌の増殖剤
HU183430B (en) * 1981-05-12 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing cyclodextrine inclusion complexes of n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine or n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine-hydrochloride
DE3372705D1 (en) * 1982-04-30 1987-09-03 Takeda Chemical Industries Ltd Pharmaceutical composition and its use
JPS6140298A (ja) * 1984-06-30 1986-02-26 Zeria Shinyaku Kogyo Kk シクロアルテノ−ルフエルラ酸エステル−シクロデキストリン複合体
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
US5017566A (en) * 1987-12-30 1991-05-21 University Of Florida Redox systems for brain-targeted drug delivery
US5007966A (en) * 1988-09-21 1991-04-16 American Maize-Products Company Cyclodextrin complexing method
US5997856A (en) * 1988-10-05 1999-12-07 Chiron Corporation Method and compositions for solubilization and stabilization of polypeptides, especially proteins
US5602112A (en) * 1992-06-19 1997-02-11 Supergen, Inc. Pharmaceutical formulation
US20040014695A1 (en) * 1992-06-19 2004-01-22 Supergen, Inc. Pharmaceutical formulation
US5824668A (en) * 1996-11-07 1998-10-20 Supergen, Inc. Formulation for administration of steroid compounds
US5942501A (en) * 1996-08-16 1999-08-24 Collaborative Laboratories, Inc. Cyclodextrin derivative complex
US20070009532A1 (en) * 2005-07-06 2007-01-11 Branimir Sikic Treatment of patients with cancer using a calicheamicin-antibody conjugate in combination with zosuquidar
US20070010487A1 (en) * 2005-07-06 2007-01-11 Jeff Schwegman Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins
US20070010485A1 (en) * 2005-07-06 2007-01-11 Jeff Schwegman Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins
US20070010478A1 (en) * 2005-07-06 2007-01-11 Branimir Sikic Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer
US20070010486A1 (en) * 2005-07-06 2007-01-11 Jeff Schwegman Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins
US10532102B2 (en) 2016-08-19 2020-01-14 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical composition and methods of uses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE895769C (de) * 1951-08-26 1953-11-05 Knoll Ag Verfahren zur Herstellung von Einschlussverbindungen physiologisch wirksamer organischer Verbindungen
HU179141B (es) * 1977-09-23 1982-08-28
HU176215B (en) * 1978-01-27 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1

Also Published As

Publication number Publication date
US4352793A (en) 1982-10-05
ES490848A0 (es) 1981-04-16
EP0018773B1 (en) 1983-06-22
EP0018773A1 (en) 1980-11-12
DE3063842D1 (en) 1983-07-28
MX5999E (es) 1984-09-18
HU183129B (en) 1984-04-28
CA1146545A (en) 1983-05-17

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