JPS56113712A - Production of pharmaceutical preparation of bencyclane fumarate - Google Patents
Production of pharmaceutical preparation of bencyclane fumarateInfo
- Publication number
- JPS56113712A JPS56113712A JP1704280A JP1704280A JPS56113712A JP S56113712 A JPS56113712 A JP S56113712A JP 1704280 A JP1704280 A JP 1704280A JP 1704280 A JP1704280 A JP 1704280A JP S56113712 A JPS56113712 A JP S56113712A
- Authority
- JP
- Japan
- Prior art keywords
- fumarate
- bencyclane fumarate
- cyclodextrin
- water
- bencyclane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: To obtain the titled pharmaceutical preparation with its side effect extremely reduced, by blending bencyclane fumarate with cyclodextrin.
CONSTITUTION: Bencyclane fumarate [3-[(1-benzylcycloheptyl)oxy]-N,N-dimethylpropylamine fumarate] having anticonvulsive and vasodilating actions on the market is blended with cyclodextrin, preferably in water or a mixed solvent of water and a water-mixcible organic solvent (e.g., ethanol), to give a parmaceutical preparation of bencyclane fumarate. Bencyclane fumarate reduces stimulation, lowers the inhibiting action on its discharge from the stomach, increases stability in an acidic region by its inclusion in cyclodextrin, to improve the absorbing properties from the stomach and intestine.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1704280A JPS56113712A (en) | 1980-02-13 | 1980-02-13 | Production of pharmaceutical preparation of bencyclane fumarate |
US06/138,562 US4352793A (en) | 1979-04-26 | 1980-04-08 | Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin |
CA000349526A CA1146545A (en) | 1979-04-26 | 1980-04-10 | Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin |
AT80301315T ATE3812T1 (en) | 1979-04-26 | 1980-04-23 | PHARMACEUTICAL COMPOSITION CONTAINING BENCYCLAN FUMARATE, A PROCESS FOR THE PREPARATION THEREOF AND AN INCLUSION COMPOUND CONTAINING BENCYCLAN FUMARATE. |
DE8080301315T DE3063842D1 (en) | 1979-04-26 | 1980-04-23 | A pharmaceutical composition containing bencyclane fumarate, a process for its preparation and an inclusion compound containing bencyclane fumarate |
EP80301315A EP0018773B1 (en) | 1979-04-26 | 1980-04-23 | A pharmaceutical composition containing bencyclane fumarate, a process for its preparation and an inclusion compound containing bencyclane fumarate |
ES490848A ES8103972A1 (en) | 1979-04-26 | 1980-04-24 | A pharmaceutical composition containing bencyclane fumarate, a process for its preparation and an inclusion compound containing bencyclane fumarate. |
MX808774U MX5999E (en) | 1979-04-26 | 1980-04-24 | PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS CONTAINING BENCICLANUM FUMARATE AND CYCLODEXTRIN |
CS293480A CS227308B2 (en) | 1979-04-26 | 1980-04-25 | Method of preparing pharmaceutical compositions |
HU801038A HU183129B (en) | 1979-04-26 | 1980-04-25 | Pharmaceutical compositions containing bencyclane-fumarate and cyclodextrin and process for the production thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1704280A JPS56113712A (en) | 1980-02-13 | 1980-02-13 | Production of pharmaceutical preparation of bencyclane fumarate |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56113712A true JPS56113712A (en) | 1981-09-07 |
Family
ID=11932935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1704280A Pending JPS56113712A (en) | 1979-04-26 | 1980-02-13 | Production of pharmaceutical preparation of bencyclane fumarate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56113712A (en) |
-
1980
- 1980-02-13 JP JP1704280A patent/JPS56113712A/en active Pending
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