JPS56113712A - Production of pharmaceutical preparation of bencyclane fumarate - Google Patents

Production of pharmaceutical preparation of bencyclane fumarate

Info

Publication number
JPS56113712A
JPS56113712A JP1704280A JP1704280A JPS56113712A JP S56113712 A JPS56113712 A JP S56113712A JP 1704280 A JP1704280 A JP 1704280A JP 1704280 A JP1704280 A JP 1704280A JP S56113712 A JPS56113712 A JP S56113712A
Authority
JP
Japan
Prior art keywords
fumarate
bencyclane fumarate
cyclodextrin
water
bencyclane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1704280A
Other languages
Japanese (ja)
Inventor
Yoshinari Yamahira
Takeshi Noguchi
Takaharu Fujioka
Tetsuo Noguchi
Shigeji Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP1704280A priority Critical patent/JPS56113712A/en
Priority to US06/138,562 priority patent/US4352793A/en
Priority to CA000349526A priority patent/CA1146545A/en
Priority to AT80301315T priority patent/ATE3812T1/en
Priority to DE8080301315T priority patent/DE3063842D1/en
Priority to EP80301315A priority patent/EP0018773B1/en
Priority to ES490848A priority patent/ES8103972A1/en
Priority to MX808774U priority patent/MX5999E/en
Priority to CS293480A priority patent/CS227308B2/en
Priority to HU801038A priority patent/HU183129B/en
Publication of JPS56113712A publication Critical patent/JPS56113712A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: To obtain the titled pharmaceutical preparation with its side effect extremely reduced, by blending bencyclane fumarate with cyclodextrin.
CONSTITUTION: Bencyclane fumarate [3-[(1-benzylcycloheptyl)oxy]-N,N-dimethylpropylamine fumarate] having anticonvulsive and vasodilating actions on the market is blended with cyclodextrin, preferably in water or a mixed solvent of water and a water-mixcible organic solvent (e.g., ethanol), to give a parmaceutical preparation of bencyclane fumarate. Bencyclane fumarate reduces stimulation, lowers the inhibiting action on its discharge from the stomach, increases stability in an acidic region by its inclusion in cyclodextrin, to improve the absorbing properties from the stomach and intestine.
COPYRIGHT: (C)1981,JPO&Japio
JP1704280A 1979-04-26 1980-02-13 Production of pharmaceutical preparation of bencyclane fumarate Pending JPS56113712A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP1704280A JPS56113712A (en) 1980-02-13 1980-02-13 Production of pharmaceutical preparation of bencyclane fumarate
US06/138,562 US4352793A (en) 1979-04-26 1980-04-08 Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
CA000349526A CA1146545A (en) 1979-04-26 1980-04-10 Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
AT80301315T ATE3812T1 (en) 1979-04-26 1980-04-23 PHARMACEUTICAL COMPOSITION CONTAINING BENCYCLAN FUMARATE, A PROCESS FOR THE PREPARATION THEREOF AND AN INCLUSION COMPOUND CONTAINING BENCYCLAN FUMARATE.
DE8080301315T DE3063842D1 (en) 1979-04-26 1980-04-23 A pharmaceutical composition containing bencyclane fumarate, a process for its preparation and an inclusion compound containing bencyclane fumarate
EP80301315A EP0018773B1 (en) 1979-04-26 1980-04-23 A pharmaceutical composition containing bencyclane fumarate, a process for its preparation and an inclusion compound containing bencyclane fumarate
ES490848A ES8103972A1 (en) 1979-04-26 1980-04-24 A pharmaceutical composition containing bencyclane fumarate, a process for its preparation and an inclusion compound containing bencyclane fumarate.
MX808774U MX5999E (en) 1979-04-26 1980-04-24 PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS CONTAINING BENCICLANUM FUMARATE AND CYCLODEXTRIN
CS293480A CS227308B2 (en) 1979-04-26 1980-04-25 Method of preparing pharmaceutical compositions
HU801038A HU183129B (en) 1979-04-26 1980-04-25 Pharmaceutical compositions containing bencyclane-fumarate and cyclodextrin and process for the production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1704280A JPS56113712A (en) 1980-02-13 1980-02-13 Production of pharmaceutical preparation of bencyclane fumarate

Publications (1)

Publication Number Publication Date
JPS56113712A true JPS56113712A (en) 1981-09-07

Family

ID=11932935

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1704280A Pending JPS56113712A (en) 1979-04-26 1980-02-13 Production of pharmaceutical preparation of bencyclane fumarate

Country Status (1)

Country Link
JP (1) JPS56113712A (en)

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