ES2110098T3 - Procedimiento de produccion de formulaciones para medicamentos. - Google Patents
Procedimiento de produccion de formulaciones para medicamentos.Info
- Publication number
- ES2110098T3 ES2110098T3 ES93914852T ES93914852T ES2110098T3 ES 2110098 T3 ES2110098 T3 ES 2110098T3 ES 93914852 T ES93914852 T ES 93914852T ES 93914852 T ES93914852 T ES 93914852T ES 2110098 T3 ES2110098 T3 ES 2110098T3
- Authority
- ES
- Spain
- Prior art keywords
- mold
- production procedure
- drug formulations
- disclosed
- longitudinal axis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/02—Dies; Inserts therefor; Mounting thereof; Moulds
- B30B15/022—Moulds for compacting material in powder, granular of pasta form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/007—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a plurality of pressing members working in different directions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
- A61M2202/066—Powder made from a compacted product by abrading
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S425/00—Plastic article or earthenware shaping or treating: apparatus
- Y10S425/014—Expansible and collapsible
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S425/00—Plastic article or earthenware shaping or treating: apparatus
- Y10S425/044—Rubber mold
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Saccharide Compounds (AREA)
Abstract
SE DESCRIBE UN PROCESO PARA LA PRODUCCION DE CUERPOS COMPACTADOS DE MEDICAMENTOS EN POLVO, COMPRENDIENDO DICHO PROCESO LOS PASOS DE: A) POSICIONADO DE ELEMENTOS EXPANSIBLES A LO LARGO DEL EJE LONGITUDINAL DEL MOLDE; B) COLOCACION DEL MEDICAMENTO EN FORMA DE POLVO SUELTO EN EL MOLDE, Y C) EXPANSION DE LOS ELEMENTOS EXPANSIBLES PERPENDICULARMENTE AL EJE LONGITUDINAL DEL MOLDE. TAMBIEN SE DESCRIBEN UN APARATO PARA USO EN EL PROCESO DE ACUERDO DE ACUERDO CON LA INVENCION Y MEDICAMENTOS COMPACTOS FORMADOS POR DICHO PROCESO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929213874A GB9213874D0 (en) | 1992-06-30 | 1992-06-30 | Process to novel medicament form |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2110098T3 true ES2110098T3 (es) | 1998-02-01 |
Family
ID=10717946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93914852T Expired - Lifetime ES2110098T3 (es) | 1992-06-30 | 1993-06-30 | Procedimiento de produccion de formulaciones para medicamentos. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5976436A (es) |
EP (1) | EP0650410B1 (es) |
JP (1) | JP3477201B2 (es) |
AT (1) | ATE160725T1 (es) |
CA (1) | CA2137826C (es) |
DE (1) | DE69315578T2 (es) |
DK (1) | DK0650410T3 (es) |
ES (1) | ES2110098T3 (es) |
GB (1) | GB9213874D0 (es) |
GR (1) | GR3026059T3 (es) |
WO (1) | WO1994000291A1 (es) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL111194A (en) * | 1993-10-08 | 1998-02-08 | Fisons Plc | Process for the production of drug patramulations |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
DE4436854A1 (de) * | 1994-10-15 | 1996-04-18 | Ggu Gesundheits Umweltforsch | Arzneistoff-Vorrat zur mechanischen Freisetzung von lungengängigen Wirkstoff-Aerosolen für die inhalative Applikation von Arzneistoffen |
US5676967A (en) * | 1995-04-18 | 1997-10-14 | Brennen Medical, Inc. | Mesh matrix wound dressing |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
US7442388B2 (en) | 2000-05-10 | 2008-10-28 | Weers Jeffry G | Phospholipid-based powders for drug delivery |
US7134623B2 (en) * | 2001-05-17 | 2006-11-14 | Rader Companies | Hammermill |
BR0209839B1 (pt) * | 2001-05-17 | 2010-11-30 | moinho de martelos. | |
CA2468958C (en) | 2001-12-19 | 2012-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
PT1572217E (pt) | 2002-12-12 | 2008-11-28 | Nycomed Gmbh | Medicamento combinado de r,r-formoterol e ciclesonida |
MY143936A (en) | 2003-03-27 | 2011-07-29 | Nycomed Gmbh | Process for preparing crystalline ciclesonide with defined particle size |
PL1670482T5 (pl) | 2003-09-16 | 2022-10-03 | Covis Pharma Gmbh | Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego |
US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
DE102004026969A1 (de) * | 2004-06-02 | 2005-12-29 | Sms Meer Gmbh | Vorrichtung zum Herstellen eines Formteils aus Pulver |
CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
HUE028691T2 (en) | 2005-09-14 | 2016-12-28 | Mannkind Corp | A method for formulating a drug based on increasing the affinity of crystalline microparticle surfaces towards active ingredients |
US20070178049A1 (en) * | 2005-12-20 | 2007-08-02 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile |
US20070197486A1 (en) * | 2005-12-20 | 2007-08-23 | Verus Pharmaceuticals, Inc. | Methods and systems for the delivery of corticosteroids |
US20070160542A1 (en) * | 2005-12-20 | 2007-07-12 | Verus Pharmaceuticals, Inc. | Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile |
US20070249572A1 (en) * | 2005-12-20 | 2007-10-25 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids |
US20070185066A1 (en) * | 2005-12-20 | 2007-08-09 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids |
CA2642577A1 (en) * | 2006-02-15 | 2007-08-23 | Tika Lakemedel Ab | Methods of manufacturing corticosteroid solutions |
EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
AR072114A1 (es) | 2008-06-13 | 2010-08-04 | Mannkind Corp | Un inhalador de polvo seco y sistema para suministro de farmacos |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
BRPI0914308B8 (pt) | 2008-06-20 | 2021-06-22 | Mannkind Corp | sistema de inalação |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
EP2344126A1 (en) * | 2008-10-14 | 2011-07-20 | Activaero GmbH | Method for treatment of copd and other pulmonary diseases |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US9060927B2 (en) | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
AR079451A1 (es) | 2009-12-18 | 2012-01-25 | Nycomed Gmbh | Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina |
RU2571331C1 (ru) | 2010-06-21 | 2015-12-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
JP6133270B2 (ja) | 2011-04-01 | 2017-05-24 | マンカインド コーポレイション | 薬剤カートリッジのためのブリスター包装 |
US20140113877A1 (en) | 2011-06-15 | 2014-04-24 | Takeda Gmbh | Novel 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c] isoquinoline compounds |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
CA2837248A1 (en) | 2011-06-17 | 2012-12-20 | Takeda Gmbh | Novel phthalazinone -pyrrolopyrimidinecarboxamide derivatives |
JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
SG11201500218VA (en) | 2012-07-12 | 2015-03-30 | Mannkind Corp | Dry powder drug delivery systems and methods |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
WO2014144895A1 (en) | 2013-03-15 | 2014-09-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
AU2014290438B2 (en) | 2013-07-18 | 2019-11-07 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
WO2018069210A1 (en) | 2016-10-10 | 2018-04-19 | Takeda Gmbh | Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US950567A (en) * | 1908-11-30 | 1910-03-01 | Granville Kesling | Pipe and tile mold. |
US2312381A (en) * | 1940-10-24 | 1943-03-02 | Frank J Bickenheuser | Medicinal tablet |
US2587215A (en) * | 1949-04-27 | 1952-02-26 | Frank P Priestly | Inhalator |
GB881701A (en) * | 1959-09-11 | 1961-11-08 | Ici Ltd | Production of hollow articles from polytetrafluoroethylene |
FR1346567A (fr) * | 1962-12-26 | 1963-12-20 | Asea Ab | Appareil à haute pression, notamment pour la transformation du graphite en diamant |
US3561079A (en) * | 1968-03-11 | 1971-02-09 | Robinson Clay Product Co The | Apparatus for pressing of clay pipe using an elastomeric mandrel |
US3583200A (en) * | 1969-05-19 | 1971-06-08 | Grotnes Machine Works Inc | Expanding head and improved seal therefor |
US4039703A (en) * | 1973-11-13 | 1977-08-02 | Sumitomo Electric Industries, Ltd. | Method for producing a tubular multi-layered porous barrier |
US5288497A (en) * | 1985-05-01 | 1994-02-22 | The University Of Utah | Compositions of oral dissolvable medicaments |
CA2007683A1 (en) * | 1989-02-03 | 1990-08-03 | James C. Danly, Sr. | Composite and self-lubricating bushing and method for making same |
ATE111364T1 (de) * | 1989-05-31 | 1994-09-15 | Fisons Plc | Medikament und inhalationsvorrichtung dafür. |
US5176132A (en) * | 1989-05-31 | 1993-01-05 | Fisons Plc | Medicament inhalation device and formulation |
-
1992
- 1992-06-30 GB GB929213874A patent/GB9213874D0/en active Pending
-
1993
- 1993-06-30 ES ES93914852T patent/ES2110098T3/es not_active Expired - Lifetime
- 1993-06-30 AT AT93914852T patent/ATE160725T1/de not_active IP Right Cessation
- 1993-06-30 CA CA002137826A patent/CA2137826C/en not_active Expired - Lifetime
- 1993-06-30 WO PCT/GB1993/001375 patent/WO1994000291A1/en active IP Right Grant
- 1993-06-30 DE DE69315578T patent/DE69315578T2/de not_active Expired - Lifetime
- 1993-06-30 JP JP50218294A patent/JP3477201B2/ja not_active Expired - Lifetime
- 1993-06-30 DK DK93914852.4T patent/DK0650410T3/da active
- 1993-06-30 EP EP93914852A patent/EP0650410B1/en not_active Expired - Lifetime
-
1997
- 1997-03-20 US US08/821,383 patent/US5976436A/en not_active Expired - Lifetime
-
1998
- 1998-02-04 GR GR980400227T patent/GR3026059T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2137826A1 (en) | 1994-01-06 |
ATE160725T1 (de) | 1997-12-15 |
JP3477201B2 (ja) | 2003-12-10 |
WO1994000291A1 (en) | 1994-01-06 |
GB9213874D0 (en) | 1992-08-12 |
CA2137826C (en) | 2005-01-25 |
EP0650410B1 (en) | 1997-12-03 |
DK0650410T3 (da) | 1998-05-25 |
EP0650410A1 (en) | 1995-05-03 |
DE69315578T2 (de) | 1998-04-02 |
GR3026059T3 (en) | 1998-05-29 |
DE69315578D1 (de) | 1998-01-15 |
JPH07508194A (ja) | 1995-09-14 |
US5976436A (en) | 1999-11-02 |
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