DK0644199T3 - Cykliske antimikrobielle peptider og fremstilling deraf - Google Patents

Cykliske antimikrobielle peptider og fremstilling deraf

Info

Publication number
DK0644199T3
DK0644199T3 DK94107406T DK94107406T DK0644199T3 DK 0644199 T3 DK0644199 T3 DK 0644199T3 DK 94107406 T DK94107406 T DK 94107406T DK 94107406 T DK94107406 T DK 94107406T DK 0644199 T3 DK0644199 T3 DK 0644199T3
Authority
DK
Denmark
Prior art keywords
preparation
hydroxy
hydrogen
antimicrobial peptides
cyclic antimicrobial
Prior art date
Application number
DK94107406T
Other languages
Danish (da)
English (en)
Inventor
Hisashi Takasugi
Hidenori Ohki
Masaki Tomishima
Akira Yamada
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310091A external-priority patent/GB9310091D0/en
Priority claimed from GB939325269A external-priority patent/GB9325269D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0644199T3 publication Critical patent/DK0644199T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK94107406T 1993-05-17 1994-05-12 Cykliske antimikrobielle peptider og fremstilling deraf DK0644199T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939310091A GB9310091D0 (en) 1993-05-17 1993-05-17 New polypeptide compound and a process for preparation thereof
GB939325269A GB9325269D0 (en) 1993-12-10 1993-12-10 New polypeptide compound and a process for preparation thereof

Publications (1)

Publication Number Publication Date
DK0644199T3 true DK0644199T3 (da) 2000-09-18

Family

ID=26302903

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94107406T DK0644199T3 (da) 1993-05-17 1994-05-12 Cykliske antimikrobielle peptider og fremstilling deraf

Country Status (18)

Country Link
US (2) US5569646A (zh)
EP (1) EP0644199B1 (zh)
JP (1) JP3551469B2 (zh)
KR (1) KR100346489B1 (zh)
CN (1) CN1057306C (zh)
AT (1) ATE194846T1 (zh)
AU (1) AU681119B2 (zh)
CA (1) CA2123921A1 (zh)
DE (1) DE69425304T2 (zh)
DK (1) DK0644199T3 (zh)
ES (1) ES2148254T3 (zh)
GR (1) GR3034366T3 (zh)
HU (1) HUT68385A (zh)
IL (1) IL109615A (zh)
PH (1) PH30811A (zh)
PT (1) PT644199E (zh)
RU (1) RU2164230C2 (zh)
TW (1) TW301655B (zh)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874403A (en) * 1992-10-15 1999-02-23 Merck & Co., Inc. Amino acid conjugates of cyclohexapeptidyl amines
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
EP0846699A1 (en) * 1995-06-29 1998-06-10 Fujisawa Pharmaceutical Co., Ltd. Substance wf16616, process for production thereof, and use thereof
WO1997017365A1 (en) * 1995-11-09 1997-05-15 Merck & Co., Inc. Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use
US6117641A (en) * 1996-04-11 2000-09-12 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents and uses related thereto
WO1997038293A2 (en) 1996-04-11 1997-10-16 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US6727082B1 (en) 1996-04-11 2004-04-27 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US5854212A (en) * 1996-10-23 1998-12-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
JP3561917B2 (ja) * 1998-02-09 2004-09-08 藤沢薬品工業株式会社 新規化合物
EP1064299A1 (en) * 1998-03-16 2001-01-03 Fujisawa Pharmaceutical Co., Ltd. Cyclohexapeptide wf14573 or its salt, production thereof and use thereof
PT1073675E (pt) 1998-04-23 2007-03-30 Aventis Pharma Gmbh Processo para a conversão de péptidos da classe da equinocandina nos seus análogos monodesoxilo da c4-homotirosina
AU6408499A (en) * 1998-10-05 2000-04-26 Abbott Laboratories Cyclic peptides as antifungal agents
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
FR2794747B1 (fr) * 1999-06-09 2004-04-16 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
AUPR362001A0 (en) * 2001-03-08 2001-04-05 Fujisawa Pharmaceutical Co., Ltd. New compound
BRPI0820409A2 (pt) * 2007-10-29 2015-05-19 Astellas Pharma Inc Composto de polipeptídeo
EP2408802B1 (en) 2009-03-16 2017-05-03 The Governing Council of the University of Toronto Cyclic amino acid molecules and methods of preparing the same
US8927801B2 (en) * 2009-04-13 2015-01-06 The Procter & Gamble Company Absorbent articles comprising wetness indicators
JP2014088326A (ja) * 2011-02-22 2014-05-15 Astellas Pharma Inc ポリペプチド化合物
CN102512379B (zh) * 2011-12-16 2017-03-08 深圳市健元医药科技有限公司 一种新型棘白菌素类抗真菌药物组合物及其制备方法
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102786591B (zh) * 2012-08-31 2014-03-12 哈尔滨工业大学 定向诱导合成金属硫蛋白的工艺
AU2016353547B9 (en) 2015-11-11 2020-12-03 Universite De Montreal Cyclic peptides targeting α4β7 integrin
CA3042576A1 (en) 2016-11-11 2018-05-17 Encycle Therapeutics, Inc. Cyclic peptides multimers targeting .alpha.4.beta.7 integrin
IL270465B (en) 2017-05-10 2022-09-01 Encycle Therapeutics Inc Cyclic peptides targeting alpha4beta7 integrin
CN112759627B (zh) * 2021-03-12 2021-10-01 河南科技大学 一种抗白色念珠菌多肽及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5159059A (en) * 1990-05-29 1992-10-27 Merck & Co., Inc. Process for reduction of certain cyclohexapeptide compounds
FI912873A (fi) * 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
WO1994009033A1 (en) * 1992-10-16 1994-04-28 Merck & Co., Inc. An improved process for cyclohexapeptidyl bisamine compounds

Also Published As

Publication number Publication date
ATE194846T1 (de) 2000-08-15
TW301655B (zh) 1997-04-01
JPH06340693A (ja) 1994-12-13
CN1057306C (zh) 2000-10-11
US5569646A (en) 1996-10-29
IL109615A0 (en) 1994-08-26
EP0644199B1 (en) 2000-07-19
JP3551469B2 (ja) 2004-08-04
HU9401515D0 (en) 1994-08-29
EP0644199A1 (en) 1995-03-22
DE69425304T2 (de) 2000-12-21
CN1100104A (zh) 1995-03-15
GR3034366T3 (en) 2000-12-29
DE69425304D1 (de) 2000-08-24
RU2164230C2 (ru) 2001-03-20
CA2123921A1 (en) 1994-11-18
PH30811A (en) 1997-10-17
AU681119B2 (en) 1997-08-21
IL109615A (en) 2000-12-06
US5693750A (en) 1997-12-02
PT644199E (pt) 2001-01-31
KR100346489B1 (ko) 2002-11-18
AU6199494A (en) 1994-11-24
ES2148254T3 (es) 2000-10-16
HUT68385A (en) 1995-06-28

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