DK0620733T3 - Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf - Google Patents

Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf

Info

Publication number
DK0620733T3
DK0620733T3 DK93901850T DK93901850T DK0620733T3 DK 0620733 T3 DK0620733 T3 DK 0620733T3 DK 93901850 T DK93901850 T DK 93901850T DK 93901850 T DK93901850 T DK 93901850T DK 0620733 T3 DK0620733 T3 DK 0620733T3
Authority
DK
Denmark
Prior art keywords
pct
nifedipine
pharmaceutical compositions
preparation
compositions containing
Prior art date
Application number
DK93901850T
Other languages
Danish (da)
English (en)
Inventor
David Trigger
Original Assignee
Ethical Pharmaceuticals U K Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethical Pharmaceuticals U K Li filed Critical Ethical Pharmaceuticals U K Li
Application granted granted Critical
Publication of DK0620733T3 publication Critical patent/DK0620733T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
DK93901850T 1992-01-13 1993-01-12 Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf DK0620733T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929200607A GB9200607D0 (en) 1992-01-13 1992-01-13 Pharmaceutical compositions containing nifedipine and process for the preparation thereof
PCT/GB1993/000055 WO1993013773A1 (en) 1992-01-13 1993-01-12 Pharmaceutical compositions containing nifedipine and process for the preparation thereof

Publications (1)

Publication Number Publication Date
DK0620733T3 true DK0620733T3 (da) 2000-07-24

Family

ID=10708487

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93901850T DK0620733T3 (da) 1992-01-13 1993-01-12 Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf
DK083794A DK83794A (da) 1992-01-13 1994-07-11 Farmaceutiske præparater indeholdende nifedipin og fremgangsmåde til fremstilling heraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK083794A DK83794A (da) 1992-01-13 1994-07-11 Farmaceutiske præparater indeholdende nifedipin og fremgangsmåde til fremstilling heraf

Country Status (24)

Country Link
US (1) US5594013A (pt)
EP (1) EP0620733B1 (pt)
JP (1) JPH07503003A (pt)
AT (1) ATE191144T1 (pt)
AU (1) AU659529B2 (pt)
CA (1) CA2126864A1 (pt)
DE (2) DE69328245T2 (pt)
DK (2) DK0620733T3 (pt)
ES (1) ES2146227T3 (pt)
FI (1) FI943316A0 (pt)
GB (2) GB9200607D0 (pt)
HU (2) HU219338B (pt)
IS (1) IS1620B (pt)
MY (1) MY110660A (pt)
NL (1) NL9320021A (pt)
NO (1) NO305223B1 (pt)
NZ (1) NZ246374A (pt)
PH (1) PH30985A (pt)
PL (1) PL170935B1 (pt)
PT (1) PT620733E (pt)
RU (1) RU2106139C1 (pt)
SE (1) SE9402457L (pt)
WO (1) WO1993013773A1 (pt)
ZA (1) ZA93195B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005262A1 (en) * 1992-09-10 1994-03-17 F.H. Faulding & Co. Limited Sustained release matrix composition
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
AU7106996A (en) * 1995-09-07 1997-03-27 Fuisz Technologies Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
CO4771151A1 (es) * 1996-01-19 1999-04-30 Rachitzky Falicman Pablo Alberto Procedimiento para la elaboracion de una preparacion farmace utica que contiene nifedipina y la preparacion farmaceutica obtenida mediante el mismo
AU695734B2 (en) 1996-07-08 1998-08-20 Penwest Pharmaceuticals Co. Sustained release matrix for high-dose insoluble drugs
IT1284604B1 (it) * 1996-09-27 1998-05-21 Roberto Valducci Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva
US5922352A (en) * 1997-01-31 1999-07-13 Andrx Pharmaceuticals, Inc. Once daily calcium channel blocker tablet having a delayed release core
US5837379A (en) * 1997-01-31 1998-11-17 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6264872B1 (en) 1997-12-30 2001-07-24 Kimberly-Clark Worldwide, Inc. Method of forming thin, embossed, textured barrier films
US6969529B2 (en) 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6168806B1 (en) 1999-03-05 2001-01-02 Fang-Yu Lee Orally administrable nifedipine pellet and process for the preparation thereof
EP1341521B1 (en) * 2000-11-20 2009-01-07 Elan Pharma International Limited Nanoparticulate compositions comprising a drug and copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
SE0100200D0 (sv) * 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
ES2233876T3 (es) * 2001-12-19 2005-06-16 Astrazeneca Ab Nuevo recubrimiento de pelicula que contiene un copolimero acrilato de etilo/metacrilato de metilo y poli (acetato de vinilo).
US6620900B2 (en) * 2002-02-07 2003-09-16 Isp Investments Inc. Proliferous copolymer of vinyl pyrrolidone and vinyl acetate
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US20070078513A1 (en) * 2002-09-18 2007-04-05 Medtronic Vascular, Inc. Controllable drug releasing gradient coatings for medical devices
US9713592B2 (en) 2005-04-06 2017-07-25 Mallinckrodt Llc Matrix-based pulse release pharmaceutical formulation
WO2007106111A2 (en) * 2005-07-01 2007-09-20 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising nilvadipine
EP2214651A1 (en) * 2007-10-25 2010-08-11 Bayer Yakuhin, Ltd. Nifedipine-containing press coated tablet and method of preparing the same
RU2629843C1 (ru) * 2016-05-24 2017-09-04 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) Способ получения мази нифедипина (варианты)

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2400819C2 (de) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
ATE16500T1 (de) * 1980-09-05 1985-11-15 Argus Chem Homogene, lagerbestaendige, fluessige bariumcadmium-triphosphit-stabilisierungssysteme fuer polyvinylchloridharze.
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
JPS5846019A (ja) * 1981-09-14 1983-03-17 Kanebo Ltd 持続性ニフエジピン製剤
EP0078430B2 (de) * 1981-10-29 1993-02-10 Bayer Ag Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen
EP0159604B1 (en) * 1984-04-09 1990-11-07 Toyo Boseki Kabushiki Kaisha Sustained-release preparation applicable to mucous membrane in oral cavity
DE3424553A1 (de) * 1984-07-04 1986-01-09 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
IT1178511B (it) * 1984-09-14 1987-09-09 Pharmatec Spa Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
DE3438830A1 (de) * 1984-10-23 1986-04-30 Rentschler Arzneimittel Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung
FR2579510B1 (fr) * 1985-03-29 1989-12-15 Demler Sa Ets Table vibrante pour la fabrication de produits en beton
FR2585174B1 (fr) * 1985-07-16 1987-11-27 Eurofarad Procede de fabrication d'un composant capacitif multicouche a dielectrique ceramique du type cordierite, et composant ainsi obtenu
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
GB8613689D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US4970075A (en) * 1986-07-18 1990-11-13 Euroceltique, S.A. Controlled release bases for pharmaceuticals
IE59540B1 (en) * 1987-01-09 1994-03-09 Elan Corp Sustained release capsule or tablet formulation
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
DE69020758T2 (de) * 1989-03-10 1995-12-07 Yamanouchi Pharma Co Ltd Die Wirkstoffabgabe steuerndes Überzugsmaterial für lang wirksame Formulierungen.
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
JPH0729926B2 (ja) * 1989-07-25 1995-04-05 大塚製薬株式会社 易吸収性製剤用組成物

Also Published As

Publication number Publication date
IS3966A (is) 1993-07-14
US5594013A (en) 1997-01-14
GB9413101D0 (en) 1994-08-31
NO942622L (no) 1994-07-12
AU659529B2 (en) 1995-05-18
NZ246374A (en) 1995-07-26
DE69328245D1 (de) 2000-05-04
EP0620733A1 (en) 1994-10-26
EP0620733B1 (en) 2000-03-29
RU94035739A (ru) 1996-09-20
HU9401850D0 (en) 1994-09-28
ES2146227T3 (es) 2000-08-01
AU3263693A (en) 1993-08-03
GB9200607D0 (en) 1992-03-11
DK83794A (da) 1994-07-11
HUT67426A (en) 1995-04-28
PT620733E (pt) 2000-08-31
CA2126864A1 (en) 1993-07-22
SE9402457D0 (sv) 1994-07-12
GB2277872B (en) 1995-10-04
PH30985A (en) 1997-12-23
ZA93195B (en) 1993-08-16
NO305223B1 (no) 1999-04-26
NL9320021A (nl) 1995-06-01
SE9402457L (sv) 1994-09-12
FI943316A (fi) 1994-07-12
PL300638A1 (en) 1994-03-21
JPH07503003A (ja) 1995-03-30
DE69328245T2 (de) 2000-10-12
WO1993013773A1 (en) 1993-07-22
HU219338B (en) 2001-03-28
NO942622D0 (no) 1994-07-12
FI943316A0 (fi) 1994-07-12
DE4390075T1 (de) 1994-12-01
MY110660A (en) 1999-01-30
GB2277872A (en) 1994-11-16
HU210539A9 (en) 1995-05-29
IS1620B (is) 1996-10-18
ATE191144T1 (de) 2000-04-15
RU2106139C1 (ru) 1998-03-10
PL170935B1 (pl) 1997-02-28

Similar Documents

Publication Publication Date Title
DK0620733T3 (da) Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf
AU635021B2 (en) Extended release pharmaceutical formulations
ATE153022T1 (de) 3',5'-ditertbutyl-4'-hydroxyflavone, verfahren zu ihrer herstellung und pharmazeutische zusammensetzung mit antioxidations- und antivasokonstriktionsaktivität
DK0626843T3 (da) Anvendelse af polyvinylpyrrolidon til nedsættelse af orale bakteriers adhærens
DE59104271D1 (de) Lösungsmittelfreie, oral zu verabreichende pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung und verfahren zu deren herstellung.
ATE150735T1 (de) Lagerstabil verkapseltes natriumpercarbonat und verfahren zu seiner herstellung
DE69617030T2 (de) VERFAHREN ZUM MARKIEREN VON GEGENSTäNDEN SOWIE NACH DIESEM VERFAHREN MARKIERTE GEGENSTäNDE
DE69305080D1 (de) Alginatfasern mit verzögerter wirkstofffreigabe und verfahren zu deren herstellung
ATE246515T1 (de) Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac
CO4761022A1 (es) Pesticidas que contienen alcaloides de benzofenantridina
DK0689441T3 (da) Farmaceutisk præparat i form af et kit omfattende prostaglandin E1
ATE104848T1 (de) Trapidil enthaltende pharmazeutische zusammensetzungen und verfahren zu ihrer herstellung.
DE68913257D1 (de) Gegenstand aus Kristall und Verfahren zu seiner Herstellung.
DK8291D0 (da) Praeparat omfattende en aktiv bestanddel, fortrinsvis i pulver- eller partikelform, samt en baerer for den aktive bestanddel og fremgangsmaade til fremstilling af et saadant praeparat
ATE145647T1 (de) Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen