DK0605638T3 - Metalalkoxider - Google Patents

Metalalkoxider

Info

Publication number
DK0605638T3
DK0605638T3 DK92921317T DK92921317T DK0605638T3 DK 0605638 T3 DK0605638 T3 DK 0605638T3 DK 92921317 T DK92921317 T DK 92921317T DK 92921317 T DK92921317 T DK 92921317T DK 0605638 T3 DK0605638 T3 DK 0605638T3
Authority
DK
Denmark
Prior art keywords
group
metal alkoxides
hydrogen
hydroxy protecting
baccatin iii
Prior art date
Application number
DK92921317T
Other languages
Danish (da)
English (en)
Inventor
Robert A Holton
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State filed Critical Univ Florida State
Application granted granted Critical
Publication of DK0605638T3 publication Critical patent/DK0605638T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Saccharide Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
DK92921317T 1991-09-23 1992-09-22 Metalalkoxider DK0605638T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76380591A 1991-09-23 1991-09-23
US07/862,778 US5229526A (en) 1991-09-23 1992-04-03 Metal alkoxides
PCT/US1992/007952 WO1993006094A1 (en) 1991-09-23 1992-09-22 Metal alkoxides

Publications (1)

Publication Number Publication Date
DK0605638T3 true DK0605638T3 (da) 2000-02-28

Family

ID=27117339

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92921317T DK0605638T3 (da) 1991-09-23 1992-09-22 Metalalkoxider

Country Status (24)

Country Link
US (1) US5229526A (ja)
EP (1) EP0605638B1 (ja)
JP (1) JP3320416B2 (ja)
CN (1) CN1058714C (ja)
AT (1) ATE184004T1 (ja)
AU (1) AU643911B2 (ja)
CA (1) CA2098568C (ja)
CZ (1) CZ289299B6 (ja)
DE (1) DE69229916T2 (ja)
DK (1) DK0605638T3 (ja)
ES (1) ES2137951T3 (ja)
FI (1) FI109796B (ja)
HU (1) HU225914B1 (ja)
IL (1) IL103192A (ja)
MX (1) MX9205370A (ja)
MY (1) MY128481A (ja)
NO (1) NO305120B1 (ja)
NZ (1) NZ244458A (ja)
PH (1) PH30213A (ja)
PT (1) PT100884B (ja)
RU (1) RU2098413C1 (ja)
TW (1) TW368502B (ja)
UA (1) UA41287C2 (ja)
WO (1) WO1993006094A1 (ja)

Families Citing this family (97)

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US5430160A (en) 1991-09-23 1995-07-04 Florida State University Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
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US6521660B2 (en) 1991-09-23 2003-02-18 Florida State University 3′-alkyl substituted taxanes and pharmaceutical compositions containing them
US5728725A (en) * 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5998656A (en) * 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
US6335362B1 (en) * 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US6011056A (en) * 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US6005138A (en) 1991-09-23 1999-12-21 Florida State University Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US6028205A (en) * 1991-09-23 2000-02-22 Florida State University C2 tricyclic taxanes
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
ZA926829B (en) * 1991-09-23 1993-03-15 Univ Florida State Novel substituted taxanes and pharmaceutical compositions containing them.
US5284865A (en) * 1991-09-23 1994-02-08 Holton Robert A Cyclohexyl substituted taxanes and pharmaceutical compositions containing them
US5710287A (en) * 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5721268A (en) 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US7074945B2 (en) * 1991-09-23 2006-07-11 Florida State University Metal alkoxide taxane derivatives
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5489601A (en) * 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
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US5646176A (en) 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
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US6187916B1 (en) * 1993-02-01 2001-02-13 Research Foundation Of State University Of New York Process for the preparation of taxane derivatives and β-lactam intermediates therefor
ZA94128B (en) * 1993-02-01 1994-08-19 Univ New York State Res Found Process for the preparation of taxane derivatives and betalactam intermediates therefor
US6593482B2 (en) 1993-02-01 2003-07-15 Aventis Pharma S.A. Methods for preparing new taxoids and pharmaceutical compositions containing them
ES2193154T3 (es) * 1993-03-05 2003-11-01 Univ Florida State Procedimiento para la preparacion de 9-desoxotaxanos.
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
US5547981A (en) * 1993-03-09 1996-08-20 Enzon, Inc. Taxol-7-carbazates
TW467896B (en) 1993-03-19 2001-12-11 Bristol Myers Squibb Co Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
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IL109049A (en) * 1993-03-22 2006-12-31 Univ Florida State Texans have a side chain that is converted into pyridyl and pharmaceutical preparations that contain them
DE69432141T2 (de) * 1993-03-22 2003-07-31 Florida State University, Tallahassee Taxane mit furyl-oder thienyl substituierten seitenketten
IT1261667B (it) * 1993-05-20 1996-05-29 Tassano ad attivita' antitumorale.
KR101222904B1 (ko) 1993-07-19 2013-01-17 안지오테크 파마슈티칼즈, 인코포레이티드 항맥관형성 조성물, 당해 조성물로 피복된 스텐트 및 당해 스텐트의 제조방법
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US5405972A (en) * 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
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US6500858B2 (en) 1994-10-28 2002-12-31 The Research Foundation Of The State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
US6100411A (en) * 1994-10-28 2000-08-08 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
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US5760251A (en) * 1995-08-11 1998-06-02 Sepracor, Inc. Taxol process and compounds
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FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone

Also Published As

Publication number Publication date
HU225914B1 (en) 2007-12-28
NO305120B1 (no) 1999-04-06
MX9205370A (es) 1993-03-31
FI941323A (fi) 1994-03-22
AU643911B2 (en) 1993-11-25
EP0605638B1 (en) 1999-09-01
FI109796B (fi) 2002-10-15
HU9400831D0 (en) 1994-06-28
JPH07502982A (ja) 1995-03-30
DE69229916D1 (de) 1999-10-07
IL103192A0 (en) 1993-02-21
ES2137951T3 (es) 2000-01-01
HUT66398A (en) 1994-11-28
EP0605638A1 (en) 1994-07-13
PH30213A (en) 1997-02-05
CA2098568C (en) 1997-06-03
CN1058714C (zh) 2000-11-22
JP3320416B2 (ja) 2002-09-03
IL103192A (en) 1997-06-10
PT100884B (pt) 1999-07-30
AU2688892A (en) 1993-04-27
US5229526A (en) 1993-07-20
CZ289299B6 (cs) 2001-12-12
ATE184004T1 (de) 1999-09-15
PT100884A (pt) 1993-11-30
UA41287C2 (uk) 2001-09-17
EP0605638A4 (en) 1994-08-24
NO941020D0 (no) 1994-03-22
MY128481A (en) 2007-02-28
FI941323A0 (fi) 1994-03-22
WO1993006094A1 (en) 1993-04-01
CN1075718A (zh) 1993-09-01
NO941020L (no) 1994-05-20
TW368502B (en) 1999-09-01
NZ244458A (en) 1994-06-27
DE69229916T2 (de) 2000-02-17
CZ66294A3 (en) 1994-12-15
CA2098568A1 (en) 1993-03-24
RU2098413C1 (ru) 1997-12-10

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