DK0605474T3 - Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraser - Google Patents
Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraserInfo
- Publication number
- DK0605474T3 DK0605474T3 DK92919058T DK92919058T DK0605474T3 DK 0605474 T3 DK0605474 T3 DK 0605474T3 DK 92919058 T DK92919058 T DK 92919058T DK 92919058 T DK92919058 T DK 92919058T DK 0605474 T3 DK0605474 T3 DK 0605474T3
- Authority
- DK
- Denmark
- Prior art keywords
- thiaphysovenin
- methods
- pharmaceutical preparations
- compounds
- cholinesterases
- Prior art date
Links
- 150000004657 carbamic acid derivatives Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 102000003914 Cholinesterases Human genes 0.000 title 1
- 108090000322 Cholinesterases Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 108010053652 Butyrylcholinesterase Proteins 0.000 abstract 1
- 102100032404 Cholinesterase Human genes 0.000 abstract 1
- 239000000544 cholinesterase inhibitor Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76576691A | 1991-09-26 | 1991-09-26 | |
| US84508192A | 1992-03-03 | 1992-03-03 | |
| PCT/US1992/007085 WO1993005779A1 (en) | 1991-09-26 | 1992-08-26 | Carbamate analogs of thiaphysovenine, pharmaceutical compositions, and method for inhibiting cholinesterases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0605474T3 true DK0605474T3 (da) | 2004-02-23 |
Family
ID=27117648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92919058T DK0605474T3 (da) | 1991-09-26 | 1992-08-26 | Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraser |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5378723A (enExample) |
| EP (2) | EP0605474B1 (enExample) |
| JP (1) | JP3193717B2 (enExample) |
| AT (1) | ATE254916T1 (enExample) |
| AU (1) | AU667318B2 (enExample) |
| CA (1) | CA2119782C (enExample) |
| DE (1) | DE69233255T2 (enExample) |
| DK (1) | DK0605474T3 (enExample) |
| ES (1) | ES2206449T3 (enExample) |
| WO (1) | WO1993005779A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2255170T3 (es) * | 1997-07-09 | 2006-06-16 | Axonyx | Inhibidores de butirilcolinesterasa altamente selectivos para el tratamiento y diagnostico de demencias y de la enfermedad de alzheimer. |
| US6534541B1 (en) | 1999-10-19 | 2003-03-18 | Novartis Ag | Treatment of ocular disorders |
| DE60135579D1 (de) | 2000-11-02 | 2008-10-09 | Us Gov Health & Human Serv | Wirkstoffe für die verminderung von amyloid precursor protein und die behandlung von schwachsinn, und deren verfahren der verwendung |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP1718294A4 (en) * | 2004-01-30 | 2007-10-03 | Axonyx Inc | METHODS OF TREATING COMPLICATIONS OF DIABETES |
| DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
| KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료 |
| WO2010095940A2 (en) | 2009-02-20 | 2010-08-26 | To-Bbb Holding B.V. | Glutathione-based drug delivery system |
| TWI556839B (zh) | 2009-05-06 | 2016-11-11 | 研究室護膚股份有限公司 | 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| KR101667215B1 (ko) | 2014-10-21 | 2016-10-18 | 한밭대학교 산학협력단 | 신규한 트립타민 컨쥬게이트 화합물 및 그의 용도 |
| KR102233120B1 (ko) | 2018-12-18 | 2021-03-29 | 한밭대학교 산학협력단 | 신규한 파에오놀-트립타민 화합물 및 그의 용도 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3133930A (en) * | 1961-08-15 | 1964-05-19 | Ciba Geigy Corp | Ester and amide derivatives of thieno-[3, 2-b] indole 3-carboxylic acids |
| US4900748A (en) * | 1988-03-04 | 1990-02-13 | The United States Of America As Represented By The Department Of Health And Human Services | Carbamates related to (-)-physostigmine as cholinergic agents |
-
1992
- 1992-08-26 JP JP50604593A patent/JP3193717B2/ja not_active Expired - Fee Related
- 1992-08-26 WO PCT/US1992/007085 patent/WO1993005779A1/en not_active Ceased
- 1992-08-26 CA CA002119782A patent/CA2119782C/en not_active Expired - Fee Related
- 1992-08-26 ES ES92919058T patent/ES2206449T3/es not_active Expired - Lifetime
- 1992-08-26 EP EP92919058A patent/EP0605474B1/en not_active Expired - Lifetime
- 1992-08-26 DK DK92919058T patent/DK0605474T3/da active
- 1992-08-26 DE DE69233255T patent/DE69233255T2/de not_active Expired - Fee Related
- 1992-08-26 AU AU25042/92A patent/AU667318B2/en not_active Ceased
- 1992-08-26 AT AT92919058T patent/ATE254916T1/de not_active IP Right Cessation
- 1992-08-28 EP EP02013799A patent/EP1251131A3/en not_active Withdrawn
-
1994
- 1994-01-18 US US08/182,301 patent/US5378723A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU667318B2 (en) | 1996-03-21 |
| DE69233255D1 (de) | 2004-01-08 |
| EP1251131A3 (en) | 2002-10-30 |
| ES2206449T3 (es) | 2004-05-16 |
| EP1251131A2 (en) | 2002-10-23 |
| EP0605474A4 (enExample) | 1994-08-03 |
| DE69233255T2 (de) | 2004-05-27 |
| JPH07505120A (ja) | 1995-06-08 |
| ATE254916T1 (de) | 2003-12-15 |
| CA2119782C (en) | 2005-08-23 |
| EP0605474A1 (en) | 1994-07-13 |
| AU2504292A (en) | 1993-04-27 |
| JP3193717B2 (ja) | 2001-07-30 |
| US5378723A (en) | 1995-01-03 |
| CA2119782A1 (en) | 1993-04-01 |
| EP0605474B1 (en) | 2003-11-26 |
| WO1993005779A1 (en) | 1993-04-01 |
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