DK0605474T3 - Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraser - Google Patents

Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraser

Info

Publication number
DK0605474T3
DK0605474T3 DK92919058T DK92919058T DK0605474T3 DK 0605474 T3 DK0605474 T3 DK 0605474T3 DK 92919058 T DK92919058 T DK 92919058T DK 92919058 T DK92919058 T DK 92919058T DK 0605474 T3 DK0605474 T3 DK 0605474T3
Authority
DK
Denmark
Prior art keywords
thiaphysovenin
methods
pharmaceutical preparations
compounds
cholinesterases
Prior art date
Application number
DK92919058T
Other languages
English (en)
Inventor
Arnold Brossi
Xiao-Shu He
Stanley I Rapoport
Nigel H Greig
Malgarzota Brzostowska
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of DK0605474T3 publication Critical patent/DK0605474T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK92919058T 1991-09-26 1992-08-26 Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraser DK0605474T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76576691A 1991-09-26 1991-09-26
US84508192A 1992-03-03 1992-03-03
PCT/US1992/007085 WO1993005779A1 (en) 1991-09-26 1992-08-26 Carbamate analogs of thiaphysovenine, pharmaceutical compositions, and method for inhibiting cholinesterases

Publications (1)

Publication Number Publication Date
DK0605474T3 true DK0605474T3 (da) 2004-02-23

Family

ID=27117648

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92919058T DK0605474T3 (da) 1991-09-26 1992-08-26 Carbamatanaloger af thiaphysovenin, farmaceutiske præparater og fremgangsmåder til inhibering af cholinesteraser

Country Status (10)

Country Link
US (1) US5378723A (da)
EP (2) EP0605474B1 (da)
JP (1) JP3193717B2 (da)
AT (1) ATE254916T1 (da)
AU (1) AU667318B2 (da)
CA (1) CA2119782C (da)
DE (1) DE69233255T2 (da)
DK (1) DK0605474T3 (da)
ES (1) ES2206449T3 (da)
WO (1) WO1993005779A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04001462A (es) * 1997-07-09 2005-04-29 Nat Inst Health Inhibidores de butirilcolinesterasa altamente selectivos para el tratamiento y la diagnosis de la enfermedad de alzheimer y demencias.
US6534541B1 (en) 1999-10-19 2003-03-18 Novartis Ag Treatment of ocular disorders
CA2465534C (en) * 2000-11-02 2009-10-27 Nigel H. Greig Agents useful for reducing amyloid precursor protein and treating dementia and methods of use thereof
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
US20070129350A1 (en) * 2004-01-30 2007-06-07 Axonyx, Inc. Methods for treatment of diabetes
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
JP5564517B2 (ja) 2009-02-20 2014-07-30 ティーオー − ビービービー ホールディング ベスローテン フェンノートシャップ グルタチオンをベースとする薬物送達システム
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR101667215B1 (ko) 2014-10-21 2016-10-18 한밭대학교 산학협력단 신규한 트립타민 컨쥬게이트 화합물 및 그의 용도
KR102233120B1 (ko) 2018-12-18 2021-03-29 한밭대학교 산학협력단 신규한 파에오놀-트립타민 화합물 및 그의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133930A (en) * 1961-08-15 1964-05-19 Ciba Geigy Corp Ester and amide derivatives of thieno-[3, 2-b] indole 3-carboxylic acids
US4900748A (en) * 1988-03-04 1990-02-13 The United States Of America As Represented By The Department Of Health And Human Services Carbamates related to (-)-physostigmine as cholinergic agents

Also Published As

Publication number Publication date
ATE254916T1 (de) 2003-12-15
CA2119782A1 (en) 1993-04-01
EP0605474A4 (da) 1994-08-03
EP0605474B1 (en) 2003-11-26
US5378723A (en) 1995-01-03
EP1251131A3 (en) 2002-10-30
CA2119782C (en) 2005-08-23
ES2206449T3 (es) 2004-05-16
DE69233255T2 (de) 2004-05-27
AU2504292A (en) 1993-04-27
DE69233255D1 (de) 2004-01-08
AU667318B2 (en) 1996-03-21
JP3193717B2 (ja) 2001-07-30
EP0605474A1 (en) 1994-07-13
JPH07505120A (ja) 1995-06-08
EP1251131A2 (en) 2002-10-23
WO1993005779A1 (en) 1993-04-01

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