ATE254916T1 - Carbamatanalogen von thiaphysovenin, pharmazeutische zusammensetzungen und verfahren zur hemmung von cholinesterasen - Google Patents

Carbamatanalogen von thiaphysovenin, pharmazeutische zusammensetzungen und verfahren zur hemmung von cholinesterasen

Info

Publication number
ATE254916T1
ATE254916T1 AT92919058T AT92919058T ATE254916T1 AT E254916 T1 ATE254916 T1 AT E254916T1 AT 92919058 T AT92919058 T AT 92919058T AT 92919058 T AT92919058 T AT 92919058T AT E254916 T1 ATE254916 T1 AT E254916T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
thiaphysovenin
carbamat
analogues
methods
Prior art date
Application number
AT92919058T
Other languages
English (en)
Inventor
Arnold Brossi
Xiao-Shu He
Stanley I Rapoport
Nigel H Greig
Malgarzota Brzostowska
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE254916T1 publication Critical patent/ATE254916T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT92919058T 1991-09-26 1992-08-26 Carbamatanalogen von thiaphysovenin, pharmazeutische zusammensetzungen und verfahren zur hemmung von cholinesterasen ATE254916T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76576691A 1991-09-26 1991-09-26
US84508192A 1992-03-03 1992-03-03
PCT/US1992/007085 WO1993005779A1 (en) 1991-09-26 1992-08-26 Carbamate analogs of thiaphysovenine, pharmaceutical compositions, and method for inhibiting cholinesterases

Publications (1)

Publication Number Publication Date
ATE254916T1 true ATE254916T1 (de) 2003-12-15

Family

ID=27117648

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92919058T ATE254916T1 (de) 1991-09-26 1992-08-26 Carbamatanalogen von thiaphysovenin, pharmazeutische zusammensetzungen und verfahren zur hemmung von cholinesterasen

Country Status (10)

Country Link
US (1) US5378723A (de)
EP (2) EP0605474B1 (de)
JP (1) JP3193717B2 (de)
AT (1) ATE254916T1 (de)
AU (1) AU667318B2 (de)
CA (1) CA2119782C (de)
DE (1) DE69233255T2 (de)
DK (1) DK0605474T3 (de)
ES (1) ES2206449T3 (de)
WO (1) WO1993005779A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4522499B2 (ja) * 1997-07-09 2010-08-11 トレーパインズ セラピューティクス インコーポレイテッド アルツハイマー病及び痴呆の治療及び診断のための高選択的ブチリルコリンエステラーゼ阻害薬
US6534541B1 (en) 1999-10-19 2003-03-18 Novartis Ag Treatment of ocular disorders
ATE406371T1 (de) * 2000-11-02 2008-09-15 Us Gov Health & Human Serv Wirkstoffe für die verminderung von amyloid precursor protein und die behandlung von schwachsinn, und deren verfahren der verwendung
EP1554572B1 (de) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20070129350A1 (en) * 2004-01-30 2007-06-07 Axonyx, Inc. Methods for treatment of diabetes
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
EP2063905B1 (de) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR101667215B1 (ko) 2014-10-21 2016-10-18 한밭대학교 산학협력단 신규한 트립타민 컨쥬게이트 화합물 및 그의 용도
KR102233120B1 (ko) 2018-12-18 2021-03-29 한밭대학교 산학협력단 신규한 파에오놀-트립타민 화합물 및 그의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133930A (en) * 1961-08-15 1964-05-19 Ciba Geigy Corp Ester and amide derivatives of thieno-[3, 2-b] indole 3-carboxylic acids
US4900748A (en) * 1988-03-04 1990-02-13 The United States Of America As Represented By The Department Of Health And Human Services Carbamates related to (-)-physostigmine as cholinergic agents

Also Published As

Publication number Publication date
ES2206449T3 (es) 2004-05-16
DK0605474T3 (da) 2004-02-23
CA2119782A1 (en) 1993-04-01
EP0605474B1 (de) 2003-11-26
US5378723A (en) 1995-01-03
CA2119782C (en) 2005-08-23
DE69233255D1 (de) 2004-01-08
EP1251131A3 (de) 2002-10-30
JP3193717B2 (ja) 2001-07-30
WO1993005779A1 (en) 1993-04-01
AU2504292A (en) 1993-04-27
DE69233255T2 (de) 2004-05-27
AU667318B2 (en) 1996-03-21
JPH07505120A (ja) 1995-06-08
EP0605474A4 (de) 1994-08-03
EP0605474A1 (de) 1994-07-13
EP1251131A2 (de) 2002-10-23

Similar Documents

Publication Publication Date Title
DE69332860D1 (de) Bicyklische fibrinogen antagoniste
DK0659174T3 (da) Derivater af valproinsyre og 2-valproensyreamider samt deres anvendelse som antikonvulsive midler
NZ238181A (en) N-(1-substituted-piperidinyl(alkyl))carbamic acid, urea and carboxamide derivatives and homologues thereof; preparatory processes and pharmaceutical compositions
FI862210A0 (fi) Imidazoheterocykliska foereningar och foerfarande foer deras framstaellning.
PT96324A (pt) Processo para a preparacao de compostos peptidicos e de composicoes farmaceuticas que os contem
DK163120C (da) Analogifremgangsmaade til fremstilling af substituerede acylderivater af 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyre (s,s,s) eller et farmaceutisk acceptabelt salt deraf
ES2081187T3 (es) Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ATE254916T1 (de) Carbamatanalogen von thiaphysovenin, pharmazeutische zusammensetzungen und verfahren zur hemmung von cholinesterasen
PT96916A (pt) Processo para a preparacao de composicoes farmaceuticas contendo um macrolido
DE68914292D1 (de) Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
DE69400382D1 (de) Zusammensetzung zur Förderung des Lipidmetabolismus
BR9305164A (pt) Composto, formulação farmacêutica e processo para preparar um composto
PT96030A (pt) Processo para a preparacao de aminocarbonilcarbamatos relacionados com fisoestigmina e de composicoes farmaceuticas que os contem
PT94297A (pt) Processo para a preparacao de n-hetero-aril-purin-6-aminas e de composicoes farmaceuticas que as contem
DE68926981D1 (de) Cephemverbindungen und Verfahren zu ihrer Herstellung
MX9202975A (es) Nuevos compuestos biciclicos y sus sales farmaceuticamente aceptables y procedimiento para su preparacion.
DE69232840D1 (de) Verfahren zu Herstellung von N-Halomethylpyrrolen und deren Zwischenverbindungen
EP0642504A4 (de) (3s, 4s)-delta-6-tetrahydrocannabinol-7-säuren und ihre derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES2062214T3 (es) Derivados de aminooligohidroxi inhibidores de renina.
ES2062014T3 (es) Carbonatos de 3-desmetiltiocolchicina y analogos n-acilados.
NO941757D0 (no) 1-fenylpyrrolidon-derivater med optisk aktivitet, mellomprodukter for fremstilling derav og fremgangsmåter for deres fremstilling

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0605474

Country of ref document: EP

REN Ceased due to non-payment of the annual fee