DK0587436T3 - Fremgangsmåde til fremstilling af carbapenem- og penemforbindelser og nye forbindelser involveret i fremgangsmåden - Google Patents

Fremgangsmåde til fremstilling af carbapenem- og penemforbindelser og nye forbindelser involveret i fremgangsmåden

Info

Publication number
DK0587436T3
DK0587436T3 DK93307130T DK93307130T DK0587436T3 DK 0587436 T3 DK0587436 T3 DK 0587436T3 DK 93307130 T DK93307130 T DK 93307130T DK 93307130 T DK93307130 T DK 93307130T DK 0587436 T3 DK0587436 T3 DK 0587436T3
Authority
DK
Denmark
Prior art keywords
compounds
carbapenem
penem
preparation
involved
Prior art date
Application number
DK93307130T
Other languages
Danish (da)
English (en)
Inventor
Akira Yoshida
Kozo Oda
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK0587436T3 publication Critical patent/DK0587436T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Eye Examination Apparatus (AREA)
DK93307130T 1992-09-09 1993-09-09 Fremgangsmåde til fremstilling af carbapenem- og penemforbindelser og nye forbindelser involveret i fremgangsmåden DK0587436T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24082592 1992-09-09
JP32511492 1992-12-04

Publications (1)

Publication Number Publication Date
DK0587436T3 true DK0587436T3 (da) 2000-08-07

Family

ID=26534948

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93307130T DK0587436T3 (da) 1992-09-09 1993-09-09 Fremgangsmåde til fremstilling af carbapenem- og penemforbindelser og nye forbindelser involveret i fremgangsmåden

Country Status (21)

Country Link
EP (1) EP0587436B1 (hu)
KR (1) KR100300365B1 (hu)
CN (1) CN1048494C (hu)
AT (1) ATE192747T1 (hu)
AU (1) AU661793B2 (hu)
CA (1) CA2105746A1 (hu)
CZ (1) CZ287608B6 (hu)
DE (1) DE69328600T2 (hu)
DK (1) DK0587436T3 (hu)
ES (1) ES2147743T3 (hu)
FI (1) FI104822B (hu)
GR (1) GR3033555T3 (hu)
HK (1) HK1011975A1 (hu)
HU (1) HUT65301A (hu)
IL (1) IL106959A (hu)
MX (1) MX9305548A (hu)
NO (1) NO304981B1 (hu)
NZ (1) NZ248629A (hu)
PT (1) PT587436E (hu)
RU (1) RU2070555C1 (hu)
TW (1) TW368503B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496816A (en) * 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
IN191798B (hu) 2000-11-03 2004-01-03 Ranbaxy Lab Ltd

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000828B1 (en) * 1977-08-06 1983-03-09 Beecham Group Plc Synthetic beta-lactam compounds, a process for their preparation and compositions containing them
EP0046363B1 (en) * 1980-08-16 1984-11-14 Beecham Group Plc Process for the preparation of 2-thio penem derivatives and intermediates therefor
EP0061231A1 (en) * 1981-02-04 1982-09-29 Beecham Group Plc Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
EP0060612A1 (en) * 1981-02-04 1982-09-22 Beecham Group Plc Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
US4640915A (en) * 1982-03-29 1987-02-03 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives
JPS5946288A (ja) * 1982-09-10 1984-03-15 Sanraku Inc β−ラクタム誘導体の製造方法
EP0120613A1 (en) * 1983-03-02 1984-10-03 Beecham Group Plc Penem derivatives and precursors
US4614738A (en) * 1983-03-25 1986-09-30 Schering Corporation 2-(N-heterocycloaliphaticthio)penems
US4614737A (en) * 1983-10-14 1986-09-30 Pfizer Inc. 2-dioxacycloalkylthiopenem derivatives
US4820817A (en) * 1984-09-10 1989-04-11 Merck & Co., Inc. Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid

Also Published As

Publication number Publication date
RU2070555C1 (ru) 1996-12-20
NO933195L (no) 1994-03-10
CN1048494C (zh) 2000-01-19
DE69328600D1 (de) 2000-06-15
NZ248629A (en) 1995-04-27
EP0587436B1 (en) 2000-05-10
PT587436E (pt) 2000-10-31
CN1094728A (zh) 1994-11-09
IL106959A0 (en) 1993-12-28
NO933195D0 (no) 1993-09-08
ATE192747T1 (de) 2000-05-15
CZ187493A3 (en) 1994-04-13
FI933926A0 (fi) 1993-09-08
DE69328600T2 (de) 2001-02-08
GR3033555T3 (en) 2000-09-29
HU9302547D0 (en) 1993-11-29
CA2105746A1 (en) 1994-03-10
MX9305548A (es) 1994-04-29
NO304981B1 (no) 1999-03-15
TW368503B (en) 1999-09-01
KR100300365B1 (ko) 2001-11-22
HUT65301A (en) 1994-05-02
KR940007031A (ko) 1994-04-26
AU4624393A (en) 1994-03-17
CZ287608B6 (en) 2001-01-17
ES2147743T3 (es) 2000-10-01
AU661793B2 (en) 1995-08-03
EP0587436A1 (en) 1994-03-16
IL106959A (en) 2000-06-01
FI104822B (fi) 2000-04-14
HK1011975A1 (en) 1999-07-23
FI933926A (fi) 1994-03-10

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