DK0584125T3 - Afkortede former af hepatocyt vækstfaktor (HGF) receptor - Google Patents

Afkortede former af hepatocyt vækstfaktor (HGF) receptor

Info

Publication number
DK0584125T3
DK0584125T3 DK92909513.1T DK92909513T DK0584125T3 DK 0584125 T3 DK0584125 T3 DK 0584125T3 DK 92909513 T DK92909513 T DK 92909513T DK 0584125 T3 DK0584125 T3 DK 0584125T3
Authority
DK
Denmark
Prior art keywords
growth factor
hepatocyte growth
hgf
receptor
chain
Prior art date
Application number
DK92909513.1T
Other languages
English (en)
Inventor
Paolo Comoglio
Tiziana Crepaldi
Maria Prat
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919110202A external-priority patent/GB9110202D0/en
Priority claimed from GB919124896A external-priority patent/GB9124896D0/en
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Application granted granted Critical
Publication of DK0584125T3 publication Critical patent/DK0584125T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK92909513.1T 1991-05-10 1992-04-30 Afkortede former af hepatocyt vækstfaktor (HGF) receptor DK0584125T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110202A GB9110202D0 (en) 1991-05-10 1991-05-10 Truncated forms of the hepatocyte growth factor(hgf)receptor
GB919124896A GB9124896D0 (en) 1991-11-22 1991-11-22 Truncated forms of the hepatocyte growth factor(hgf)receptor

Publications (1)

Publication Number Publication Date
DK0584125T3 true DK0584125T3 (da) 1997-09-08

Family

ID=26298888

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92909513.1T DK0584125T3 (da) 1991-05-10 1992-04-30 Afkortede former af hepatocyt vækstfaktor (HGF) receptor

Country Status (18)

Country Link
US (1) US5571509A (da)
EP (2) EP0520158A1 (da)
JP (1) JP3293823B2 (da)
AT (1) ATE155525T1 (da)
AU (1) AU651452B2 (da)
CA (1) CA2102595C (da)
DE (1) DE69220940T2 (da)
DK (1) DK0584125T3 (da)
ES (1) ES2104914T3 (da)
FI (1) FI934934A (da)
GR (1) GR3024998T3 (da)
HU (1) HUT67009A (da)
IE (1) IE921485A1 (da)
IL (1) IL101809A0 (da)
MX (1) MX9202129A (da)
MY (1) MY108614A (da)
NZ (1) NZ242645A (da)
WO (1) WO1992020792A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344321B1 (en) * 1990-06-11 2002-02-05 Gilead Sciences, Inc. Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
WO1995001376A1 (en) * 1993-06-30 1995-01-12 Pharmacia S.P.A. Peptide inhibitors of mitogenesis and motogenesis
US5464815A (en) * 1993-09-08 1995-11-07 Genentech, Inc. Inhibition of heparin-binding
US5646036A (en) * 1995-06-02 1997-07-08 Genentech, Inc. Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
WO1997009997A1 (en) * 1995-09-12 1997-03-20 Genentech, Inc. Cystic fibrosis therapy
AU7254896A (en) * 1995-10-05 1997-04-28 Genentech Inc. Improved angiogenesis using hepatocyte growth factor
WO1997012628A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Methods and compositions for treating vascular stenosis
JP2000515735A (ja) * 1996-07-03 2000-11-28 ジェネンテック インコーポレーテッド 肝細胞成長因子レセプターアゴニスト
US5874306A (en) * 1996-12-12 1999-02-23 The Regents Of The University Of California Culturing human pancreatic endocrine cells in medium containing extracellular matrix from human bladder carcinoma cells
US6759206B1 (en) 1997-02-27 2004-07-06 Cellomics, Inc. System for cell-based screening
US6031155A (en) * 1997-06-05 2000-02-29 Cameron-Mills; Verena Arabinoxylan degradation
AU2760602A (en) * 2001-03-23 2002-09-26 Agouron Pharmaceuticals, Inc. Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
US20040248157A1 (en) * 2001-09-14 2004-12-09 Michal Ayalon-Soffer Novel polynucleotides encoding soluble polypeptides and methods using same
WO2007036945A2 (en) * 2005-09-30 2007-04-05 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US20100183573A1 (en) * 2001-09-14 2010-07-22 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US20070082337A1 (en) * 2004-01-27 2007-04-12 Compugen Ltd. Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby
US7678769B2 (en) * 2001-09-14 2010-03-16 Compugen, Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
ITMI20031127A1 (it) 2003-06-05 2004-12-06 Uni Degli Studi Del Piemont E Orientale Am Anticorpi anti-hgf-r e loro uso
DK1636593T5 (da) * 2003-06-06 2009-07-27 Genentech Inc Modulering af vekselvirkningen mellem HGF-beta-kæde og c-met
US20050233960A1 (en) * 2003-12-11 2005-10-20 Genentech, Inc. Methods and compositions for inhibiting c-met dimerization and activation
WO2005071058A2 (en) * 2004-01-27 2005-08-04 Compugen Ltd. Methods and systems for annotating biomolecular sequences
PT1773885E (pt) 2004-08-05 2010-07-21 Genentech Inc Antagonistas anti-cmet humanizados
KR101259655B1 (ko) 2005-04-15 2013-04-30 제넨테크, 인크. Ｈｇｆ 베타 사슬 변이체
EP2004693B1 (en) 2006-03-30 2012-06-06 Novartis AG Compositions and methods of use for antibodies of c-met
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
IL198545A0 (en) 2008-05-14 2011-07-31 Metheresis Translational Res Sa High affinity binding site of hgfr and methods for identification of antagonists thereof
PA8849001A1 (es) * 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
KR101671378B1 (ko) * 2009-10-30 2016-11-01 삼성전자 주식회사 ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그의 용도
JP2013532627A (ja) 2010-07-01 2013-08-19 武田薬品工業株式会社 ｃＭＥＴ阻害剤とＨＧＦおよび／またはｃＭＥＴに対する抗体との組み合わせ
CN107090038A (zh) 2011-06-30 2017-08-25 霍夫曼-拉罗奇有限公司 抗c‑met抗体配制剂
EP2758430A4 (en) 2011-09-20 2015-06-03 Lilly Co Eli ANTI-C-MET ANTIBODY
BR112016021383A2 (pt) 2014-03-24 2017-10-03 Genentech Inc Método para identificar um paciente com câncer que é susceptível ou menos susceptível a responder ao tratamento com um antagonista de cmet, método para identificar um paciente apresentando câncer previamente tratado, método para determinar a expressão do biomarcador hgf, antagonista anti-c-met e seu uso, kit de diagnóstico e seu método de preparo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648273A (en) * 1989-12-27 1997-07-15 The United States Of America, As Represented By The Department Of Health And Human Services Hepatic growth factor receptor is the MET proto-oncogene
CA2070995A1 (en) * 1989-12-27 1991-06-28 Thomas E. Kmiecik Diagnostic probe for detecting human stomach cancer

Also Published As

Publication number Publication date
MY108614A (en) 1996-10-31
EP0584125B1 (en) 1997-07-16
HUT67009A (en) 1995-01-30
EP0520158A1 (en) 1992-12-30
GR3024998T3 (en) 1998-01-30
FI934934A (fi) 1994-01-05
CA2102595A1 (en) 1992-11-11
AU651452B2 (en) 1994-07-21
ATE155525T1 (de) 1997-08-15
HU9303182D0 (en) 1994-03-28
US5571509A (en) 1996-11-05
IE921485A1 (en) 1992-11-18
DE69220940D1 (de) 1997-08-21
JPH06508508A (ja) 1994-09-29
ES2104914T3 (es) 1997-10-16
DE69220940T2 (de) 1998-01-15
FI934934A0 (fi) 1993-11-08
NZ242645A (en) 1994-11-25
AU1672092A (en) 1992-12-30
JP3293823B2 (ja) 2002-06-17
IL101809A0 (en) 1992-12-30
WO1992020792A1 (en) 1992-11-26
EP0584125A1 (en) 1994-03-02
MX9202129A (es) 1992-11-01
CA2102595C (en) 2003-01-14

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