DK0579770T3 - Makrocycliske lactamprokinetika - Google Patents

Makrocycliske lactamprokinetika

Info

Publication number
DK0579770T3
DK0579770T3 DK92911585.5T DK92911585T DK0579770T3 DK 0579770 T3 DK0579770 T3 DK 0579770T3 DK 92911585 T DK92911585 T DK 92911585T DK 0579770 T3 DK0579770 T3 DK 0579770T3
Authority
DK
Denmark
Prior art keywords
image
pct
procinetics
sec
macrocyclic lactam
Prior art date
Application number
DK92911585.5T
Other languages
Danish (da)
English (en)
Inventor
Leslie A Freiberg
Carla Edwards
Richard J Pariza
Hugh N Nellans
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0579770T3 publication Critical patent/DK0579770T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Polyamides (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK92911585.5T 1991-04-09 1992-03-30 Makrocycliske lactamprokinetika DK0579770T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68283691A 1991-04-09 1991-04-09

Publications (1)

Publication Number Publication Date
DK0579770T3 true DK0579770T3 (da) 1996-11-04

Family

ID=24741372

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92911585.5T DK0579770T3 (da) 1991-04-09 1992-03-30 Makrocycliske lactamprokinetika

Country Status (15)

Country Link
US (1) US5538961A (enExample)
EP (1) EP0579770B1 (enExample)
JP (1) JPH06509326A (enExample)
KR (1) KR100222014B1 (enExample)
AT (1) ATE139697T1 (enExample)
AU (1) AU663089B2 (enExample)
CA (1) CA2103913A1 (enExample)
DE (1) DE69211845T2 (enExample)
DK (1) DK0579770T3 (enExample)
ES (1) ES2091471T3 (enExample)
GR (1) GR3020853T3 (enExample)
IE (1) IE73236B1 (enExample)
IL (1) IL101504A (enExample)
PT (1) PT100357B (enExample)
WO (1) WO1992018134A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122261A3 (en) * 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
AU2001238476A1 (en) 2000-02-18 2001-08-27 Kosan Biosciences, Inc. Motocide compounds
EP1489090B1 (en) * 2000-08-17 2006-02-01 The Kitasato Institute Novel pseudoerythormycin derivatives
CA2429709A1 (en) * 2000-12-01 2002-07-04 Gary Ashley Motilide compounds
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
SI1532131T1 (sl) * 2002-08-29 2009-04-30 Pfizer Motilidne spojine
AU2003273318A1 (en) * 2002-09-12 2004-04-30 University Of Chicago Monitoring and diagnosis of gastric emptying and gastroparesis
CA2528375C (en) 2003-06-18 2013-11-19 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
JP2009518396A (ja) * 2005-12-08 2009-05-07 ファイザー・インク エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
RU2422453C2 (ru) * 2006-12-05 2011-06-27 Пфайзер Инк. Полиморфы мотилида
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
ES2609845T3 (es) * 2011-07-29 2017-04-24 Cambridge Epigenetix Limited Métodos para la detección de modificación de nucleótidos
ES2669512T3 (es) 2012-11-30 2018-05-28 Cambridge Epigenetix Limited Agente oxidante para nucleótidos modificados
CN115057794B (zh) * 2022-07-07 2023-11-17 桂林理工大学 一种可见光诱导铈催化氧化酰胺去甲基化的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
EP0215355B1 (en) * 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
US5008249A (en) * 1985-08-31 1991-04-16 Kitasato Kenkyusho Therapeutic method of stimulating digestive tract contractile motion in mammals
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
US5202434A (en) * 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers

Also Published As

Publication number Publication date
EP0579770A4 (enExample) 1994-03-30
IL101504A (en) 1998-04-05
CA2103913A1 (en) 1992-10-10
JPH06509326A (ja) 1994-10-20
IE73236B1 (en) 1997-05-21
KR100222014B1 (ko) 1999-10-01
ES2091471T3 (es) 1996-11-01
PT100357B (pt) 1999-06-30
EP0579770B1 (en) 1996-06-26
GR3020853T3 (en) 1996-11-30
DE69211845T2 (de) 1997-01-23
US5538961A (en) 1996-07-23
PT100357A (pt) 1993-07-30
WO1992018134A1 (en) 1992-10-29
EP0579770A1 (en) 1994-01-26
IE921045A1 (en) 1992-10-21
AU663089B2 (en) 1995-09-28
AU1910392A (en) 1992-11-17
IL101504A0 (en) 1992-12-30
DE69211845D1 (de) 1996-08-01
ATE139697T1 (de) 1996-07-15

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