ATE139697T1 - Macrozyklische laktam-prokinetika - Google Patents

Macrozyklische laktam-prokinetika

Info

Publication number
ATE139697T1
ATE139697T1 AT92911585T AT92911585T ATE139697T1 AT E139697 T1 ATE139697 T1 AT E139697T1 AT 92911585 T AT92911585 T AT 92911585T AT 92911585 T AT92911585 T AT 92911585T AT E139697 T1 ATE139697 T1 AT E139697T1
Authority
AT
Austria
Prior art keywords
image
pct
prokinetics
sec
macrocyclic lactam
Prior art date
Application number
AT92911585T
Other languages
German (de)
English (en)
Inventor
Leslie A Freiberg
Carla Edwards
Richard J Pariza
Hugh N Nellans
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE139697T1 publication Critical patent/ATE139697T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polyamides (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92911585T 1991-04-09 1992-03-30 Macrozyklische laktam-prokinetika ATE139697T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68283691A 1991-04-09 1991-04-09

Publications (1)

Publication Number Publication Date
ATE139697T1 true ATE139697T1 (de) 1996-07-15

Family

ID=24741372

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92911585T ATE139697T1 (de) 1991-04-09 1992-03-30 Macrozyklische laktam-prokinetika

Country Status (15)

Country Link
US (1) US5538961A (enExample)
EP (1) EP0579770B1 (enExample)
JP (1) JPH06509326A (enExample)
KR (1) KR100222014B1 (enExample)
AT (1) ATE139697T1 (enExample)
AU (1) AU663089B2 (enExample)
CA (1) CA2103913A1 (enExample)
DE (1) DE69211845T2 (enExample)
DK (1) DK0579770T3 (enExample)
ES (1) ES2091471T3 (enExample)
GR (1) GR3020853T3 (enExample)
IE (1) IE73236B1 (enExample)
IL (1) IL101504A (enExample)
PT (1) PT100357B (enExample)
WO (1) WO1992018134A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122261A3 (en) * 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
WO2001060833A2 (en) 2000-02-18 2001-08-23 Kosan Biosciences, Inc. Motilide compounds
KR20040074096A (ko) * 2000-08-17 2004-08-21 샤단호칭키타사토겐큐쇼 신규 슈도에리쓰로마이신 유도체
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
CA2429709A1 (en) * 2000-12-01 2002-07-04 Gary Ashley Motilide compounds
DK1532131T3 (da) * 2002-08-29 2009-02-09 Pfizer Motilid-forbindelser
JP2006510593A (ja) * 2002-09-12 2006-03-30 ザ ユニヴァーシティ オヴ シカゴ 胃内容排出及び胃不全麻痺のモニタリング及び診断
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en) 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
AU2006323175A1 (en) * 2005-12-08 2007-06-14 Pfizer, Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
KR101120483B1 (ko) * 2006-12-05 2012-02-29 브리스톨-마이어즈 스퀴브 컴페니 모틸라이드 다형체
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
AU2012291873B2 (en) 2011-07-29 2016-03-10 Cambridge Epigenetix Limited Methods for detection of nucleotide modification
US10563248B2 (en) 2012-11-30 2020-02-18 Cambridge Epigenetix Limited Oxidizing agent for modified nucleotides
CN115057794B (zh) * 2022-07-07 2023-11-17 桂林理工大学 一种可见光诱导铈催化氧化酰胺去甲基化的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US5008249A (en) * 1985-08-31 1991-04-16 Kitasato Kenkyusho Therapeutic method of stimulating digestive tract contractile motion in mammals
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
US5202434A (en) * 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers

Also Published As

Publication number Publication date
PT100357A (pt) 1993-07-30
ES2091471T3 (es) 1996-11-01
IL101504A (en) 1998-04-05
EP0579770A4 (enExample) 1994-03-30
AU1910392A (en) 1992-11-17
KR100222014B1 (ko) 1999-10-01
DE69211845T2 (de) 1997-01-23
DK0579770T3 (da) 1996-11-04
GR3020853T3 (en) 1996-11-30
CA2103913A1 (en) 1992-10-10
AU663089B2 (en) 1995-09-28
EP0579770A1 (en) 1994-01-26
IE73236B1 (en) 1997-05-21
EP0579770B1 (en) 1996-06-26
IL101504A0 (en) 1992-12-30
IE921045A1 (en) 1992-10-21
PT100357B (pt) 1999-06-30
DE69211845D1 (de) 1996-08-01
US5538961A (en) 1996-07-23
WO1992018134A1 (en) 1992-10-29
JPH06509326A (ja) 1994-10-20

Similar Documents

Publication Publication Date Title
DE69211845D1 (de) Macrozyklische laktam-prokinetika
BR9408246A (pt) Composto derivado de 3-azabicicloalcano N-substituído
HUT66660A (en) Intermediates for producing 9-[(substituted glicyl)-amido]-6-demetyl-6-deoxy-tetracyclines and pharmaceutical compositions containing them
IL98933A0 (en) Benzimidazoles,their preparation and pharmaceutical compositions containing them
IL101819A0 (en) Amidinophenylalanine derivatives,a process for the preparation thereof,use thereof and agents containing these as anticoagulants
ZA942131B (en) Pyridothiadiazines processes for their preparation and the pharmaceutical compositions which contain them
GR3022079T3 (en) Preparation of substituted piperidines
BR9206823A (pt) Preparação de piperidinas substituídas
DE3667059D1 (en) Benzodipyrroles, processes for their preparation and pharmaceutical compositions containing these compounds
EP0450420A3 (en) Dihydropyridines substituted by heterocycles, process for their preparation and their use in medicaments
DK0564358T3 (da) 3-aminochroman-spiro-derivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende sådanne
DK0484966T3 (da) 7-Acryl-3-(substitueret carbamoyloxy)cephemforbindelser, anvendelse deraf og fremgangsmåde deraf
GR3023757T3 (en) Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents.
SE9203824D0 (sv) Benzofuranylimidazole derivatives a process for the preparation and therapeutical compositions containing the same
US5162542A (en) Substituted pyrazoline derivatives
GR3015706T3 (en) Benzylselenobenzamides of aminopyridines and picolylamines.
DK0552631T3 (da) Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
IL99369A0 (en) Pharmaceutical compositions containing substituted 2-cyclohexene derivatives
IL101379A0 (en) Light screening compositions containing isoxazolones,certain such novel compounds and their preparation
IL97780A0 (en) Substituted 3-thia-and 3-oxa-alkylflavones,a process for their preparation,the use thereof,medicaments based on these compounds and intermediates
GR3029453T3 (en) NOVEL PROCESSES AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PLATELET CLYCOPROTEIN IIb/IIIa INHIBITORS

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee