DK0576439T3 - Monoklonalt antistof mod LPS-kerne - Google Patents

Monoklonalt antistof mod LPS-kerne

Info

Publication number
DK0576439T3
DK0576439T3 DK92904901T DK92904901T DK0576439T3 DK 0576439 T3 DK0576439 T3 DK 0576439T3 DK 92904901 T DK92904901 T DK 92904901T DK 92904901 T DK92904901 T DK 92904901T DK 0576439 T3 DK0576439 T3 DK 0576439T3
Authority
DK
Denmark
Prior art keywords
thr
leu
tyr
arg
ser
Prior art date
Application number
DK92904901T
Other languages
Danish (da)
English (en)
Inventor
Hermann Gram
Padova Franco Di
George Robin Barclay
Ian Raymond Poxton
Original Assignee
Common Services Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Common Services Agency filed Critical Common Services Agency
Application granted granted Critical
Publication of DK0576439T3 publication Critical patent/DK0576439T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92904901T 1991-03-13 1992-02-22 Monoklonalt antistof mod LPS-kerne DK0576439T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919105292A GB9105292D0 (en) 1991-03-13 1991-03-13 Improvements in or relating to organic compounds
PCT/EP1992/000380 WO1992016624A1 (fr) 1991-03-13 1992-02-22 Anticorps monoclonal dresse contre le noyau de lipopolysaccharide

Publications (1)

Publication Number Publication Date
DK0576439T3 true DK0576439T3 (da) 1999-11-01

Family

ID=10691487

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92904901T DK0576439T3 (da) 1991-03-13 1992-02-22 Monoklonalt antistof mod LPS-kerne

Country Status (10)

Country Link
EP (1) EP0576439B1 (fr)
JP (1) JP3328277B2 (fr)
AT (1) ATE179753T1 (fr)
AU (1) AU1261192A (fr)
CA (1) CA2105979C (fr)
DE (1) DE69229110T2 (fr)
DK (1) DK0576439T3 (fr)
ES (1) ES2131526T3 (fr)
GB (1) GB9105292D0 (fr)
WO (1) WO1992016624A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0776240B2 (ja) * 1983-05-06 1995-08-16 ベロス グル−プ エンドトキシンコア−と反応性のモノクロ−ナル抗体
US5863537A (en) * 1992-02-19 1999-01-26 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US6749831B1 (en) 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
EP1521776A2 (fr) 2002-07-04 2005-04-13 Oncomab Gmbh Anticorps specifiques de neoplasme et utilisations associees
DE10311248A1 (de) 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
EP1531162A1 (fr) 2003-11-14 2005-05-18 Heinz Vollmers Anticorps SAM-6, spécifique d'adénocarcinome, et ses utilisations
DE10353175A1 (de) 2003-11-14 2005-06-16 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper mit fettsenkender Wirkung
BRPI1014774A2 (pt) * 2009-04-27 2019-04-16 Immuron Limited preparacao de imunoglobulina enriquecida anti-lps para uso no tratamento e/ou na profilaxia de um disturbio patologico
DK2605791T3 (en) 2010-08-17 2017-06-19 Immuron Ltd ANTI-LPS ENHANCED IMMUNOGLOBULIN PREPARATION FOR USE IN TREATMENT AND / OR PROPHYLAXY OF A PATHOLOGICAL DISORDER
DE102011006781A1 (de) * 2011-04-05 2012-10-11 Mat-Malta Advanced Technologies Limited Antikörperprodukt, umfassend n spezifische Antikörper
DE102011006809A1 (de) 2011-04-05 2012-10-11 Freistaat Bayern vertreten durch die Julius-Maximilians-Universität Würzburg Verwendung eines Mittels aus Antikörpern und/oder Insulin-like growth factor-Antagonisten
US11168131B2 (en) 2015-11-10 2021-11-09 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
KR102697723B1 (ko) 2017-01-18 2024-08-21 비스테라, 인크. 항체 분자-약물 접합체 및 이의 용도
WO2021203024A1 (fr) 2020-04-03 2021-10-07 Visterra, Inc. Conjugués molécule d'anticorps-médicament et leurs utilisations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0776240B2 (ja) * 1983-05-06 1995-08-16 ベロス グル−プ エンドトキシンコア−と反応性のモノクロ−ナル抗体
JPS61130300A (ja) * 1984-11-27 1986-06-18 ザ ボ−ド オブ トラステイ−ズ オブ ザ レランド スタンフオ−ド ジユニア ユニバ−シテイ ヒトモノクロ−ナル抗体
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
FR2606421B1 (fr) * 1986-11-12 1990-01-26 Roussel Uclaf Anticorps monoclonaux antigram (-) procede de preparation et applications
GB2218703B (en) * 1988-05-10 1992-10-28 Sumitomo Chemical Co Human monoclonal antibody to p.aeruginosa: its production and use
WO1990003186A1 (fr) * 1988-09-19 1990-04-05 Cetus Corporation Endotoxine bacterienne gram negative bloquant des anticorps monoclonaux

Also Published As

Publication number Publication date
CA2105979C (fr) 2003-05-13
EP0576439B1 (fr) 1999-05-06
DE69229110D1 (de) 1999-06-10
JP3328277B2 (ja) 2002-09-24
ES2131526T3 (es) 1999-08-01
ATE179753T1 (de) 1999-05-15
WO1992016624A1 (fr) 1992-10-01
AU1261192A (en) 1992-10-21
DE69229110T2 (de) 1999-11-25
GB9105292D0 (en) 1991-04-24
EP0576439A1 (fr) 1994-01-05
CA2105979A1 (fr) 1992-09-14
JPH06505867A (ja) 1994-07-07

Similar Documents

Publication Publication Date Title
US20220267440A1 (en) Anti-cd47 antibodies
DK0576439T3 (da) Monoklonalt antistof mod LPS-kerne
CA2205007A1 (fr) Anticorpos de la chaine alpha du recepteur de l'interleukine 5 humaine
RU2017137010A (ru) Анти-сеасам6 антитела и их применения
CA2012993A1 (fr) Anticorps monoclonaux contre les antigenes associes a des tumeurs, leur preparation et leur utilisation
JP2018510636A5 (fr)
US20200347130A1 (en) CD96 Antibody, Antigen-Binding Fragment and Pharmaceutical use Thereof
MY145703A (en) Ganglioside-associated recombinant antibodies and the use thereof in the diagnosis and treatment of tumors
RU96115107A (ru) "очеловеченные" антитела и их использование
CY1113296T1 (el) Υβριδικο ανθρωπινο/τρωκτικου ιgg αντισωμα προς cd3 και μεθοδοι κατασκευης αυτου
JP6400480B2 (ja) ペプチドグリカン認識タンパク質1に結合する抗体
RU2003100512A (ru) Антитела к человеческому мср-1
CN110300764A (zh) 抗SIRPg抗体的新用途
DE3485432D1 (de) Monoklonale antikoerper mit spezifitaet fuer membran-assoziierte antigene.
CN107522783A (zh) 一种抗白介素17a 的抗体、其制备方法和应用
JP2020521504A (ja) 抗cd40抗体、その抗原結合フラグメント、およびその医学的使用
RU2013114368A (ru) Пептид или пептидный комплекс, связывающийся с альфа-интегрином, способы его получения и применения указанного вещества
CN106916225A (zh) 一种检测n端脑钠肽前体的单克隆抗体及其杂交瘤细胞株和应用
CN110461874B (zh) 抗gitr抗体、其抗原结合片段及其医药用途
CA2525657A1 (fr) Anticorps monoclonal humain specifique de lipopolysaccharides (lps) du serotype iats o6 de pseudomonas aeruginosa
KR890016165A (ko) 수도모나스 아에루기노사(Pseudomonas aeruginosa)에 대한 모노클로날 항체, 이의 제조방법 및 용도
Muneta et al. Production of monoclonal antibodies to porcine interleukin-18 and their use for immunoaffinity purification of recombinant porcine interleukin-18
CN114957468A (zh) 一种抗Siglec15抗体及其用途
JP2020172543A (ja) 骨髄細胞で発現されるトリガー受容体1(trem−1)に結合し、それを遮断する抗体
WO2024094151A1 (fr) Anticorps multi-spécifique et son utilisation médicale