DK0565549T3 - Anvendelse af 1,3-oxathiolannucleosidanaloger til fremstilling af et præparat til behandling af hepatitis B - Google Patents

Anvendelse af 1,3-oxathiolannucleosidanaloger til fremstilling af et præparat til behandling af hepatitis B

Info

Publication number
DK0565549T3
DK0565549T3 DK92901354.8T DK92901354T DK0565549T3 DK 0565549 T3 DK0565549 T3 DK 0565549T3 DK 92901354 T DK92901354 T DK 92901354T DK 0565549 T3 DK0565549 T3 DK 0565549T3
Authority
DK
Denmark
Prior art keywords
preparation
hepatitis
treatment
oxathiolannucleoside
analogues
Prior art date
Application number
DK92901354.8T
Other languages
Danish (da)
English (en)
Inventor
Bernard Belleau
Nghe Nguyen-Ba
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26298202&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0565549(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919100039A external-priority patent/GB9100039D0/en
Priority claimed from GB919109913A external-priority patent/GB9109913D0/en
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Application granted granted Critical
Publication of DK0565549T3 publication Critical patent/DK0565549T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK92901354.8T 1991-01-03 1992-01-03 Anvendelse af 1,3-oxathiolannucleosidanaloger til fremstilling af et præparat til behandling af hepatitis B DK0565549T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919100039A GB9100039D0 (en) 1991-01-03 1991-01-03 Medicaments
GB919109913A GB9109913D0 (en) 1991-05-07 1991-05-07 Medicaments

Publications (1)

Publication Number Publication Date
DK0565549T3 true DK0565549T3 (da) 1995-07-03

Family

ID=26298202

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92901354.8T DK0565549T3 (da) 1991-01-03 1992-01-03 Anvendelse af 1,3-oxathiolannucleosidanaloger til fremstilling af et præparat til behandling af hepatitis B

Country Status (23)

Country Link
US (2) US5532246A (zh)
EP (2) EP0565549B1 (zh)
JP (1) JP2659863B2 (zh)
KR (1) KR0156747B1 (zh)
AT (1) ATE120644T1 (zh)
AU (1) AU660650B2 (zh)
CA (2) CA2100269C (zh)
CY (1) CY2047B1 (zh)
DE (1) DE69201948T2 (zh)
DK (1) DK0565549T3 (zh)
EE (1) EE02995B1 (zh)
ES (1) ES2070628T3 (zh)
GE (1) GEP19981482B (zh)
GR (1) GR3015694T3 (zh)
HK (1) HK159395A (zh)
IE (1) IE73642B1 (zh)
IL (1) IL100502A (zh)
MD (1) MD1224C2 (zh)
NO (1) NO180407C (zh)
PH (1) PH31397A (zh)
TJ (1) TJ249B (zh)
TW (1) TW202385B (zh)
WO (1) WO1992011852A1 (zh)

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US20020120130A1 (en) 1993-09-10 2002-08-29 Gilles Gosselin 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
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US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5703058A (en) * 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US5808040A (en) * 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
US6689761B1 (en) 1995-02-01 2004-02-10 Merck & Co., Inc. Combination therapy for HIV infection
EP1655033A1 (en) 1995-06-07 2006-05-10 Emory University Nucleosides with anti-hepatitis B virus activity
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JP2000515852A (ja) 1996-06-25 2000-11-28 グラクソ、グループ、リミテッド Hivの治療に使用するためのvx478、ジドブジン、ftcおよび/または3tcを含んでなる組合わせ
US5753789A (en) * 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
US20030100532A1 (en) * 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
CA2285577A1 (en) 1997-04-07 1998-10-15 Triangle Pharmaceuticals, Inc. Compositions containing mkc-442 in combination with other antiviral agents
DK1104436T3 (da) 1998-08-10 2006-04-03 Centre Nat Rech Scient Beta-L-2'-deoxy-nukleosider til behandling af hepatitis B-virus
US6444652B1 (en) 1998-08-10 2002-09-03 Novirio Pharmaceuticals Limited β-L-2'-deoxy-nucleosides for the treatment of hepatitis B
ID29471A (id) 1998-11-02 2001-08-30 Triangle Pharmaceuticals Inc Terapi kombinasi untuk mengobati virus hepatitis b
US6407077B1 (en) 1998-11-05 2002-06-18 Emory University β-L nucleosides for the treatment of HIV infection
US6432966B2 (en) 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
US6436948B1 (en) 2000-03-03 2002-08-20 University Of Georgia Research Foundation Inc. Method for the treatment of psoriasis and genital warts
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
EA200601591A1 (ru) 2000-05-26 2007-02-27 Айденикс (Кайман) Лимитед Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций
US6787526B1 (en) 2000-05-26 2004-09-07 Idenix Pharmaceuticals, Inc. Methods of treating hepatitis delta virus infection with β-L-2′-deoxy-nucleosides
US6875751B2 (en) 2000-06-15 2005-04-05 Idenix Pharmaceuticals, Inc. 3′-prodrugs of 2′-deoxy-β-L-nucleosides
KR20040002871A (ko) 2001-03-01 2004-01-07 트라이앵글 파마슈티칼스 인코포레이티드 시스-ftc의 다형 및 기타 결정형
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
BR0312278A (pt) 2002-06-28 2007-06-19 Idenix Cayman Ltd éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae
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WO2004024095A2 (en) * 2002-09-13 2004-03-25 Idenix (Cayman) Limited ß-L-2'-DEOXYNUCLEOSIDES FOR THE TREATMENT OF RESISTANT HBV STRAINS AND COMBINATION THERAPIES
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US5039667A (en) * 1987-08-07 1991-08-13 The Governors Of The University Of Alberta Antiviral therapy for hepatitis B with 2',3'-dideoxypurine nucleosides
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Also Published As

Publication number Publication date
ATE120644T1 (de) 1995-04-15
USRE39155E1 (en) 2006-07-04
IL100502A (en) 1995-12-08
HK159395A (en) 1995-10-20
AU1153492A (en) 1992-08-17
CA2254613A1 (en) 1992-07-04
CA2100269A1 (en) 1992-07-04
IL100502A0 (en) 1992-09-06
EE02995B1 (et) 1997-06-16
GR3015694T3 (en) 1995-07-31
IE73642B1 (en) 1997-06-18
EP0494119A1 (en) 1992-07-08
NO932442D0 (no) 1993-07-05
JPH06507150A (ja) 1994-08-11
NO180407C (no) 1997-04-16
DE69201948D1 (de) 1995-05-11
CA2100269C (en) 1999-02-23
WO1992011852A1 (en) 1992-07-23
CY2047B1 (en) 1998-04-30
MD1224B2 (en) 1999-05-31
KR0156747B1 (en) 1998-11-16
DE69201948T2 (de) 1995-08-03
ES2070628T3 (es) 1995-06-01
MD1224C2 (ro) 1999-11-30
JP2659863B2 (ja) 1997-09-30
NO932442L (no) 1993-08-26
NO180407B (no) 1997-01-06
TW202385B (zh) 1993-03-21
AU660650B2 (en) 1995-07-06
TJ249B (en) 1999-12-23
MD950086A (ro) 1997-01-31
EP0565549B1 (en) 1995-04-05
GEP19981482B (en) 1998-12-25
EP0565549A1 (en) 1993-10-20
US5532246A (en) 1996-07-02
PH31397A (en) 1998-10-29
IE920004A1 (en) 1992-07-15

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