DK0563385T3 - Thrombolytisk peptid, fremstilling deraf og thrombolytisk middel - Google Patents

Thrombolytisk peptid, fremstilling deraf og thrombolytisk middel

Info

Publication number
DK0563385T3
DK0563385T3 DK92900924.9T DK92900924T DK0563385T3 DK 0563385 T3 DK0563385 T3 DK 0563385T3 DK 92900924 T DK92900924 T DK 92900924T DK 0563385 T3 DK0563385 T3 DK 0563385T3
Authority
DK
Denmark
Prior art keywords
thrombolytic
sak
peptide
preparation
agent
Prior art date
Application number
DK92900924.9T
Other languages
English (en)
Inventor
Osamu Matsuo
Masashi Sakai
Kisaku Shimura
Hiroshi Sansawa
Tsunekazu Watanabe
Tsumeo Matsumoto
Yoshiyuki Shishido
Shusuke Hashimoto
Teruo Yokokura
Masaharu Onoue
Tomoyuki Sako
Original Assignee
Yakult Honsha Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yakult Honsha Kk filed Critical Yakult Honsha Kk
Application granted granted Critical
Publication of DK0563385T3 publication Critical patent/DK0563385T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK92900924.9T 1990-12-17 1991-12-17 Thrombolytisk peptid, fremstilling deraf og thrombolytisk middel DK0563385T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP41106390 1990-12-17

Publications (1)

Publication Number Publication Date
DK0563385T3 true DK0563385T3 (da) 1998-05-04

Family

ID=18520124

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92900924.9T DK0563385T3 (da) 1990-12-17 1991-12-17 Thrombolytisk peptid, fremstilling deraf og thrombolytisk middel

Country Status (11)

Country Link
US (1) US5475089A (da)
EP (1) EP0563385B1 (da)
JP (1) JP2895626B2 (da)
KR (1) KR100221571B1 (da)
AT (1) ATE158613T1 (da)
AU (1) AU665935B2 (da)
CA (1) CA2098588C (da)
DE (1) DE69127757T2 (da)
DK (1) DK0563385T3 (da)
ES (1) ES2107525T3 (da)
WO (1) WO1992011356A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59206628D1 (en) * 1991-12-30 1996-07-25 Medac Klinische Spezialpraep Expression signalpeptid-freier staphylokinasen
US6383483B1 (en) * 1995-01-06 2002-05-07 Désiré José Collen Staphylokinase derivatives with cysteine substitutions
US5951980A (en) * 1995-01-06 1999-09-14 Leuven Research & Development Vzw Identification, production and use of new staphylokinase derivatives with reduced immunogenicity
CN100342007C (zh) * 2000-01-28 2007-10-10 复旦大学 一种新型重组葡激酶及其制备方法
CN110105428B (zh) * 2015-06-23 2022-08-05 首都医科大学 Leu-Arg-Ala-Pro-Leu-Tyr-Val七肽,其合成,活性和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2707273B2 (ja) * 1988-04-14 1998-01-28 株式会社ヤクルト本社 血栓溶解剤
KR0135980B1 (ko) * 1988-04-14 1998-04-25 구와하라 쥰 플라스미노겐 액티베이터 및 혈전용해제

Also Published As

Publication number Publication date
JP2895626B2 (ja) 1999-05-24
AU665935B2 (en) 1996-01-25
US5475089A (en) 1995-12-12
AU9083791A (en) 1992-07-22
DE69127757D1 (de) 1997-10-30
KR930703437A (ko) 1993-11-30
CA2098588C (en) 2003-08-19
EP0563385A4 (en) 1994-07-06
ATE158613T1 (de) 1997-10-15
EP0563385A1 (en) 1993-10-06
KR100221571B1 (ko) 1999-10-01
CA2098588A1 (en) 1992-06-18
ES2107525T3 (es) 1997-12-01
WO1992011356A1 (fr) 1992-07-09
DE69127757T2 (de) 1998-03-12
EP0563385B1 (en) 1997-09-24

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