KR930703437A - 혈전용해작용을 보유하는 펩티드, 그 제조방법 및 혈전용해제 - Google Patents

혈전용해작용을 보유하는 펩티드, 그 제조방법 및 혈전용해제

Info

Publication number
KR930703437A
KR930703437A KR1019930701826A KR930701826A KR930703437A KR 930703437 A KR930703437 A KR 930703437A KR 1019930701826 A KR1019930701826 A KR 1019930701826A KR 930701826 A KR930701826 A KR 930701826A KR 930703437 A KR930703437 A KR 930703437A
Authority
KR
South Korea
Prior art keywords
sak
thrombolysis
manufacturing
peptide
thrombolytic action
Prior art date
Application number
KR1019930701826A
Other languages
English (en)
Other versions
KR100221571B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR930703437A publication Critical patent/KR930703437A/ko
Application granted granted Critical
Publication of KR100221571B1 publication Critical patent/KR100221571B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019930701826A 1990-12-17 1991-12-17 혈전용해제 KR100221571B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP90-411063 1990-12-17
JP41106390 1990-12-17
PCT/JP1991/001722 WO1992011356A1 (fr) 1990-12-17 1991-12-17 Peptide thrombolytique, sa production et agent thrombolytique

Publications (2)

Publication Number Publication Date
KR930703437A true KR930703437A (ko) 1993-11-30
KR100221571B1 KR100221571B1 (ko) 1999-10-01

Family

ID=18520124

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930701826A KR100221571B1 (ko) 1990-12-17 1991-12-17 혈전용해제

Country Status (11)

Country Link
US (1) US5475089A (ko)
EP (1) EP0563385B1 (ko)
JP (1) JP2895626B2 (ko)
KR (1) KR100221571B1 (ko)
AT (1) ATE158613T1 (ko)
AU (1) AU665935B2 (ko)
CA (1) CA2098588C (ko)
DE (1) DE69127757T2 (ko)
DK (1) DK0563385T3 (ko)
ES (1) ES2107525T3 (ko)
WO (1) WO1992011356A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59206628D1 (en) * 1991-12-30 1996-07-25 Medac Klinische Spezialpraep Expression signalpeptid-freier staphylokinasen
US6383483B1 (en) * 1995-01-06 2002-05-07 Désiré José Collen Staphylokinase derivatives with cysteine substitutions
US5951980A (en) * 1995-01-06 1999-09-14 Leuven Research & Development Vzw Identification, production and use of new staphylokinase derivatives with reduced immunogenicity
CN100342007C (zh) * 2000-01-28 2007-10-10 复旦大学 一种新型重组葡激酶及其制备方法
CN110105428B (zh) * 2015-06-23 2022-08-05 首都医科大学 Leu-Arg-Ala-Pro-Leu-Tyr-Val七肽,其合成,活性和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2707273B2 (ja) * 1988-04-14 1998-01-28 株式会社ヤクルト本社 血栓溶解剤
KR0135980B1 (ko) * 1988-04-14 1998-04-25 구와하라 쥰 플라스미노겐 액티베이터 및 혈전용해제

Also Published As

Publication number Publication date
JP2895626B2 (ja) 1999-05-24
AU665935B2 (en) 1996-01-25
US5475089A (en) 1995-12-12
AU9083791A (en) 1992-07-22
DE69127757D1 (de) 1997-10-30
CA2098588C (en) 2003-08-19
EP0563385A4 (en) 1994-07-06
ATE158613T1 (de) 1997-10-15
EP0563385A1 (en) 1993-10-06
KR100221571B1 (ko) 1999-10-01
CA2098588A1 (en) 1992-06-18
ES2107525T3 (es) 1997-12-01
WO1992011356A1 (fr) 1992-07-09
DK0563385T3 (da) 1998-05-04
DE69127757T2 (de) 1998-03-12
EP0563385B1 (en) 1997-09-24

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Legal Events

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E701 Decision to grant or registration of patent right
GRNT Written decision to grant
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Payment date: 20110527

Year of fee payment: 13

EXPY Expiration of term