DK0533739T3 - Injicerbart farmaceutisk præparat - Google Patents
Injicerbart farmaceutisk præparatInfo
- Publication number
- DK0533739T3 DK0533739T3 DK91910762.3T DK91910762T DK0533739T3 DK 0533739 T3 DK0533739 T3 DK 0533739T3 DK 91910762 T DK91910762 T DK 91910762T DK 0533739 T3 DK0533739 T3 DK 0533739T3
- Authority
- DK
- Denmark
- Prior art keywords
- microspheres
- formulations
- contain
- dia
- microns
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000004005 microsphere Substances 0.000 abstract 8
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 2
- 239000003433 contraceptive agent Substances 0.000 abstract 2
- 230000002254 contraceptive effect Effects 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
- 239000011261 inert gas Substances 0.000 abstract 2
- 229960003387 progesterone Drugs 0.000 abstract 2
- 239000000186 progesterone Substances 0.000 abstract 2
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229960000905 indomethacin Drugs 0.000 abstract 1
- 239000000155 melt Substances 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 229960002009 naproxen Drugs 0.000 abstract 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9007416A FR2663223B1 (fr) | 1990-06-14 | 1990-06-14 | Forme galenique parenterale. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0533739T3 true DK0533739T3 (da) | 1995-01-09 |
Family
ID=9397598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91910762.3T DK0533739T3 (da) | 1990-06-14 | 1991-06-12 | Injicerbart farmaceutisk præparat |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US5360616A (cs) |
| EP (1) | EP0533739B1 (cs) |
| JP (1) | JP2675675B2 (cs) |
| KR (1) | KR0157439B1 (cs) |
| CN (1) | CN1057442C (cs) |
| AT (1) | ATE109658T1 (cs) |
| AU (1) | AU661275B2 (cs) |
| BG (1) | BG61179B1 (cs) |
| BR (1) | BR9106545A (cs) |
| CA (1) | CA2085344C (cs) |
| CZ (1) | CZ286793B6 (cs) |
| DE (1) | DE69103419T2 (cs) |
| DK (1) | DK0533739T3 (cs) |
| ES (1) | ES2059142T3 (cs) |
| FI (1) | FI107698B (cs) |
| FR (1) | FR2663223B1 (cs) |
| HU (1) | HUT68709A (cs) |
| IE (1) | IE62679B1 (cs) |
| IL (1) | IL98459A (cs) |
| NO (1) | NO302998B1 (cs) |
| NZ (1) | NZ238542A (cs) |
| PL (1) | PL167234B1 (cs) |
| PT (1) | PT97975B (cs) |
| RU (1) | RU2104692C1 (cs) |
| SK (1) | SK280564B6 (cs) |
| TN (1) | TNSN91048A1 (cs) |
| UA (1) | UA27043C2 (cs) |
| UY (1) | UY23240A1 (cs) |
| WO (1) | WO1991019484A1 (cs) |
| ZA (1) | ZA914550B (cs) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
| NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
| GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| FR2732621B1 (fr) * | 1995-04-10 | 1997-06-06 | Rhone Poulenc Chimie | Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention |
| US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
| US6028057A (en) * | 1998-02-19 | 2000-02-22 | Thorn Bioscience, Llc | Regulation of estrus and ovulation in gilts |
| JP2002504505A (ja) * | 1998-02-25 | 2002-02-12 | アボット・ラボラトリーズ | ブトルファノール持続放出性製剤 |
| US6287693B1 (en) | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
| WO2001013885A1 (en) * | 1999-08-20 | 2001-03-01 | Norton Healthcare Ltd. | Method to produce powders for pulmonary or nasal administration |
| US20070254009A1 (en) * | 2001-07-13 | 2007-11-01 | Flow Focusing, Inc. | Antibiotic/bone morphogenic protein formulation and method of treatment |
| US20030055075A1 (en) * | 2001-07-13 | 2003-03-20 | Rubsamen Reid M. | Programmable controlled release injectable opioid formulation |
| US20070254008A1 (en) * | 2001-07-13 | 2007-11-01 | Flow Focusing, Inc. | Antibiotic formulation and method of treatment |
| GB0117696D0 (en) * | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
| OA13307A (en) * | 2003-06-13 | 2007-04-13 | John Claude Savoir | Process for the manufacture of stable shaped particles consisting of estradiol and cholesterol. |
| US20050032811A1 (en) * | 2003-08-06 | 2005-02-10 | Josiah Brown | Methods for administering aripiprazole |
| KR101285137B1 (ko) | 2003-09-03 | 2013-07-11 | 미스콘 트레이딩 에스.에이. | 자궁 내막증의 치료 방법 |
| PL1684782T3 (pl) * | 2003-10-03 | 2016-03-31 | Thorn Bioscience Llc | Sposób synchronizacji owulacji dla zsynchronizowanego rozmnażania bez wykrywania rui |
| PL1675573T4 (pl) | 2003-10-23 | 2016-04-29 | Otsuka Pharma Co Ltd | Sterylny preparat do wstrzykiwań arypiprazolu o kontrolowanym uwalnianiu i sposób |
| US7413690B1 (en) | 2003-10-29 | 2008-08-19 | The University Of Mississippi | Process and apparatus for producing spherical pellets using molten solid matrices |
| US7491263B2 (en) | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
| US7392635B2 (en) * | 2005-06-09 | 2008-07-01 | Tipper Tie, Inc. | Breech loader packaging systems and associated breech loading chutes and methods |
| US20070197435A1 (en) * | 2006-02-17 | 2007-08-23 | Webel Stephen K | Process for the synchronization of ovulation for timed breeding without heat detection |
| CA2667890C (en) | 2006-10-31 | 2015-01-27 | Surmodics Pharmaceuticals, Inc. | Spheronized polymer particles |
| SI2170279T1 (en) | 2007-07-31 | 2018-04-30 | Otsuka Pharmaceutical Co., Ltd. | Methods for producing aripiprazole suspension and freeze-dried formulation |
| US20110104289A1 (en) * | 2008-04-14 | 2011-05-05 | Posi Visionary Solutions Llp | Method and pharmaceutical composition for obtaining the plasmatic progesterone levels required for different therapeutic indications |
| CN102596215B (zh) | 2009-04-23 | 2015-04-29 | 佩纳特克有限责任公司 | 用于同步授精时间的方法和组合物 |
| UY33103A (es) | 2009-12-15 | 2011-07-29 | Techsphere S A De C V | Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico |
| CN113398243A (zh) | 2012-11-28 | 2021-09-17 | 联合动物健康第二有限责任公司 | 用于同步小母猪的授精时间的方法 |
| WO2017105512A1 (en) | 2015-12-18 | 2017-06-22 | Proinvet Innovations S.A. | Formulations and methods for controlling the reproductive cycle and ovulation |
| EP3419604A4 (en) * | 2016-02-24 | 2019-10-09 | Eastern Virginia Medical School | IMPROVED FORMULATION OF A LONG-ACTING INJECTABLE DEPOTSUSPENSION OF LEVONORGESTRELBUTANOAT |
| CN106063783B (zh) * | 2016-06-16 | 2019-03-12 | 浙江爱生药业有限公司 | 一种黄体酮缓释微囊制剂及其制备方法 |
| US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
| CN115212170B (zh) * | 2021-04-19 | 2024-01-26 | 中国人民解放军军事科学院军事医学研究院 | 一种致密圆整的药物球形微晶及其制备方法和其应用 |
| CN116036022A (zh) * | 2021-12-24 | 2023-05-02 | 中国人民解放军军事科学院军事医学研究院 | 一种新型的含载体材料的药物微球制备及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE670438A (cs) * | 1964-10-06 | 1966-01-31 | ||
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3928566A (en) * | 1970-08-14 | 1975-12-23 | Du Pont | Lyophilized biological products |
| JPS5017525A (cs) * | 1973-06-14 | 1975-02-24 | ||
| CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
| US4244949A (en) * | 1978-04-06 | 1981-01-13 | The Population Council, Inc. | Manufacture of long term contraceptive implant |
| US4349580A (en) * | 1978-08-18 | 1982-09-14 | Queen's University At Kingston | Process and solution for preserving green plant tissues |
| US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
| US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
| US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
| IL79407A (en) * | 1985-08-01 | 1991-03-10 | Theragenics Corp | System and method for delivering insoluble material into a living body |
| DE3777721D1 (de) * | 1986-08-11 | 1992-04-30 | American Cyanamid Co | Zusammensetzungen zur parenteralen verabreichung und deren verwendung. |
| US4837381A (en) * | 1986-08-11 | 1989-06-06 | American Cyanamid Company | Compositions for parenteral administration and their use |
| US4892734A (en) * | 1987-04-06 | 1990-01-09 | Endocon, Inc. | Dispensing paste for forming medicinal pellets |
| US4748024A (en) * | 1987-04-06 | 1988-05-31 | Endocon, Inc. | Flash flow fused medicinal implants |
| WO1988007816A1 (en) * | 1987-04-06 | 1988-10-20 | Endocon, Inc. | Flash flow fused medicinal implants |
| WO1990013285A1 (en) * | 1989-05-01 | 1990-11-15 | Enzytech, Inc. | Process for producing small particles of biologically active molecules |
| US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
-
1990
- 1990-06-14 FR FR9007416A patent/FR2663223B1/fr not_active Expired - Fee Related
-
1991
- 1991-06-11 IL IL9845991A patent/IL98459A/en not_active IP Right Cessation
- 1991-06-12 DE DE69103419T patent/DE69103419T2/de not_active Expired - Fee Related
- 1991-06-12 ES ES91910762T patent/ES2059142T3/es not_active Expired - Lifetime
- 1991-06-12 BR BR919106545A patent/BR9106545A/pt not_active Application Discontinuation
- 1991-06-12 DK DK91910762.3T patent/DK0533739T3/da active
- 1991-06-12 AU AU80847/91A patent/AU661275B2/en not_active Ceased
- 1991-06-12 UA UA93004686A patent/UA27043C2/uk unknown
- 1991-06-12 JP JP3510331A patent/JP2675675B2/ja not_active Expired - Lifetime
- 1991-06-12 EP EP91910762A patent/EP0533739B1/fr not_active Expired - Lifetime
- 1991-06-12 HU HU9203958A patent/HUT68709A/hu unknown
- 1991-06-12 RU RU92016471A patent/RU2104692C1/ru active
- 1991-06-12 WO PCT/EP1991/001096 patent/WO1991019484A1/fr not_active Ceased
- 1991-06-12 CA CA002085344A patent/CA2085344C/en not_active Expired - Fee Related
- 1991-06-12 KR KR1019920703205A patent/KR0157439B1/ko not_active Expired - Fee Related
- 1991-06-12 AT AT91910762T patent/ATE109658T1/de not_active IP Right Cessation
- 1991-06-13 SK SK1816-91A patent/SK280564B6/sk unknown
- 1991-06-13 IE IE201791A patent/IE62679B1/en not_active IP Right Cessation
- 1991-06-13 UY UY23240A patent/UY23240A1/es not_active IP Right Cessation
- 1991-06-13 US US07/714,583 patent/US5360616A/en not_active Expired - Lifetime
- 1991-06-13 CZ CS19911816A patent/CZ286793B6/cs not_active IP Right Cessation
- 1991-06-14 NZ NZ238542A patent/NZ238542A/xx not_active IP Right Cessation
- 1991-06-14 PL PL91290677A patent/PL167234B1/pl not_active IP Right Cessation
- 1991-06-14 PT PT97975A patent/PT97975B/pt not_active IP Right Cessation
- 1991-06-14 TN TNTNSN91048A patent/TNSN91048A1/fr unknown
- 1991-06-14 ZA ZA914550A patent/ZA914550B/xx unknown
- 1991-06-14 CN CN91104859A patent/CN1057442C/zh not_active Expired - Fee Related
-
1992
- 1992-12-11 NO NO924792A patent/NO302998B1/no not_active IP Right Cessation
- 1992-12-11 FI FI925661A patent/FI107698B/fi active
- 1992-12-14 BG BG97166A patent/BG61179B1/bg unknown
-
1994
- 1994-05-17 US US08/243,823 patent/US5512303A/en not_active Expired - Lifetime
-
1996
- 1996-04-15 US US08/632,616 patent/US5633014A/en not_active Expired - Lifetime
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