DK0530286T3 - Fremgangsmåde til stereoselektiv fremstilling af phenylisoserinderivater - Google Patents

Fremgangsmåde til stereoselektiv fremstilling af phenylisoserinderivater

Info

Publication number
DK0530286T3
DK0530286T3 DK91910270.7T DK91910270T DK0530286T3 DK 0530286 T3 DK0530286 T3 DK 0530286T3 DK 91910270 T DK91910270 T DK 91910270T DK 0530286 T3 DK0530286 T3 DK 0530286T3
Authority
DK
Denmark
Prior art keywords
pct
phenylisoserine
date nov
sec
reacted
Prior art date
Application number
DK91910270.7T
Other languages
English (en)
Inventor
Arlene Correa
Jean-Noel Denis
Andrew-Elliot Greene
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0530286T3 publication Critical patent/DK0530286T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Indole Compounds (AREA)
DK91910270.7T 1990-05-22 1991-05-21 Fremgangsmåde til stereoselektiv fremstilling af phenylisoserinderivater DK0530286T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9006368A FR2662440B1 (fr) 1990-05-22 1990-05-22 Procede de preparation stereoselective de derives de la phenylisoserine.

Publications (1)

Publication Number Publication Date
DK0530286T3 true DK0530286T3 (da) 1994-09-12

Family

ID=9396838

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91910270.7T DK0530286T3 (da) 1990-05-22 1991-05-21 Fremgangsmåde til stereoselektiv fremstilling af phenylisoserinderivater

Country Status (23)

Country Link
US (1) US5290957A (da)
EP (1) EP0530286B1 (da)
JP (1) JPH05506864A (da)
AT (1) ATE109456T1 (da)
AU (1) AU648319B2 (da)
CA (1) CA2079313A1 (da)
CZ (1) CZ279927B6 (da)
DE (1) DE69103265T2 (da)
DK (1) DK0530286T3 (da)
ES (1) ES2057899T3 (da)
FI (1) FI924568A0 (da)
FR (1) FR2662440B1 (da)
HU (1) HU212728B (da)
IE (1) IE64276B1 (da)
IL (1) IL98190A (da)
NO (1) NO179942C (da)
NZ (1) NZ238206A (da)
PT (1) PT97745B (da)
RU (1) RU2091368C1 (da)
SK (1) SK277925B6 (da)
WO (1) WO1991017977A1 (da)
YU (1) YU89691A (da)
ZA (1) ZA913828B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
KR930702323A (ko) * 1991-07-17 1993-09-08 하지메 나까가와 항종양 활성을 가진 화합물(nsc-lsc1) 및 그의 제조방법
FR2680506B1 (fr) * 1991-08-19 1994-09-02 Rhone Poulenc Rorer Sa Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
KR960006762B1 (ko) * 1992-02-29 1996-05-23 삼성전자주식회사 화상부호화를 위한 효율적인 2차원 데이타의 주사선택회로
FR2696454B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane.
IL107950A (en) 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them
DE69433146T2 (de) * 1993-06-11 2004-06-09 Pharmacia & Upjohn Co., Kalamazoo Delta 6,7-Taxol Derivate antineoplastische Verbindungen und diese enthaltende pharmazeutische Zusammenstellungen
US6005120A (en) * 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
US5405972A (en) * 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
IL112412A (en) * 1994-01-28 2000-02-29 Upjohn Co Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them
WO1998049321A2 (en) * 1997-04-28 1998-11-05 Rhone-Poulenc Rorer S.A. Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
RU2534619C2 (ru) * 2009-09-23 2014-11-27 Чжэцзян Цзючжоу Фармасьютикл Ко., Лтд. Способ получения n-ацилбифенилаланина
PL2753355T3 (pl) 2011-09-08 2019-04-30 Benevir Biopharm Inc Onkolityczny wirus opryszczki pospolitej i jego zastosowania lecznicze
US9745631B2 (en) 2011-12-20 2017-08-29 Dana-Farber Cancer Institute, Inc. Methods for diagnosing and treating oncogenic kras-associated cancer
EP2855698A4 (en) 2012-05-24 2016-03-30 Dana Farber Cancer Inst Inc TARGETING THE PATHWAY FROM GLUTAMINE TO PYRUVATE TO TREAT CANCER ASSOCIATED WITH ONCOGEN KRAS
WO2014014518A1 (en) 2012-07-18 2014-01-23 Dana-Farber Cancer Institute, Inc. Methods for treating, preventing and predicting risk of developing breast cancer
WO2014149871A1 (en) 2013-03-14 2014-09-25 Icahn School Of Medicine At Mount Sinai Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
US10130590B2 (en) 2013-10-01 2018-11-20 Dana-Farber Cancer Institute, Inc. Methods of treating cancer with atovaquone-related compounds
US10350264B2 (en) 2014-03-27 2019-07-16 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating NCOA4-mediated autophagic targeting of ferritin
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
EP3307330B1 (en) 2015-06-15 2021-03-10 New York University Method of treatment using oncolytic viruses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4775782A (en) * 1987-09-30 1988-10-04 Ncr Corporation Checkout counter with remote keyboard writing pad and display
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
CA2023645C (fr) * 1989-08-23 2002-03-26 Jean-Noel Denis Procede pour la preparation enantioselective de derives de la phenylisoserine

Also Published As

Publication number Publication date
ES2057899T3 (es) 1994-10-16
AU648319B2 (en) 1994-04-21
SK277925B6 (en) 1995-08-09
EP0530286B1 (fr) 1994-08-03
DE69103265D1 (de) 1994-09-08
NO924488L (no) 1992-11-20
HUT62260A (en) 1993-04-28
ZA913828B (en) 1992-02-26
ATE109456T1 (de) 1994-08-15
JPH05506864A (ja) 1993-10-07
AU7969391A (en) 1991-12-10
IE64276B1 (en) 1995-07-26
CS9101451A2 (en) 1991-12-17
RU2091368C1 (ru) 1997-09-27
FI924568A (fi) 1992-10-09
WO1991017977A1 (fr) 1991-11-28
CA2079313A1 (fr) 1991-11-23
US5290957A (en) 1994-03-01
HU9203651D0 (en) 1993-03-29
NO179942B (no) 1996-10-07
IL98190A (en) 1995-12-31
NZ238206A (en) 1993-05-26
NO179942C (no) 1997-01-15
NO924488D0 (no) 1992-11-20
IE911737A1 (en) 1991-12-04
IL98190A0 (en) 1992-06-21
FR2662440B1 (fr) 1992-07-31
PT97745A (pt) 1992-02-28
YU89691A (sh) 1994-01-20
DE69103265T2 (de) 1994-12-22
FR2662440A1 (fr) 1991-11-29
FI924568A0 (fi) 1992-10-09
EP0530286A1 (fr) 1993-03-10
CZ279927B6 (cs) 1995-08-16
HU212728B (en) 1996-10-28
PT97745B (pt) 1998-10-30

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