DE69103265D1 - Verfahren zur stereoselektiven herstellung von phenylisoserinderivaten. - Google Patents
Verfahren zur stereoselektiven herstellung von phenylisoserinderivaten.Info
- Publication number
- DE69103265D1 DE69103265D1 DE69103265T DE69103265T DE69103265D1 DE 69103265 D1 DE69103265 D1 DE 69103265D1 DE 69103265 T DE69103265 T DE 69103265T DE 69103265 T DE69103265 T DE 69103265T DE 69103265 D1 DE69103265 D1 DE 69103265D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- derivatives
- date nov
- phenylisoser
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Semiconductor Integrated Circuits (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9006368A FR2662440B1 (fr) | 1990-05-22 | 1990-05-22 | Procede de preparation stereoselective de derives de la phenylisoserine. |
PCT/FR1991/000406 WO1991017977A1 (fr) | 1990-05-22 | 1991-05-21 | Procede de preparation stereoselective de derives de la phenylisoserine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69103265D1 true DE69103265D1 (de) | 1994-09-08 |
DE69103265T2 DE69103265T2 (de) | 1994-12-22 |
Family
ID=9396838
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69103265T Expired - Fee Related DE69103265T2 (de) | 1990-05-22 | 1991-05-21 | Verfahren zur stereoselektiven herstellung von phenylisoserinderivaten. |
Country Status (23)
Country | Link |
---|---|
US (1) | US5290957A (de) |
EP (1) | EP0530286B1 (de) |
JP (1) | JPH05506864A (de) |
AT (1) | ATE109456T1 (de) |
AU (1) | AU648319B2 (de) |
CA (1) | CA2079313A1 (de) |
CZ (1) | CZ279927B6 (de) |
DE (1) | DE69103265T2 (de) |
DK (1) | DK0530286T3 (de) |
ES (1) | ES2057899T3 (de) |
FI (1) | FI924568A0 (de) |
FR (1) | FR2662440B1 (de) |
HU (1) | HU212728B (de) |
IE (1) | IE64276B1 (de) |
IL (1) | IL98190A (de) |
NO (1) | NO179942C (de) |
NZ (1) | NZ238206A (de) |
PT (1) | PT97745B (de) |
RU (1) | RU2091368C1 (de) |
SK (1) | SK277925B6 (de) |
WO (1) | WO1991017977A1 (de) |
YU (1) | YU89691A (de) |
ZA (1) | ZA913828B (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658510B1 (fr) * | 1990-02-21 | 1992-04-30 | Rhone Poulenc Sante | Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi. |
CA2092705C (en) * | 1991-07-17 | 1995-11-07 | Koji Saito | Compound having antitumor activity, nsc-lsc1, and process for producing the same |
FR2680506B1 (fr) * | 1991-08-19 | 1994-09-02 | Rhone Poulenc Rorer Sa | Procede de preparation de derives de la beta-phenylisoserine et leur utilisation. |
US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
US5739362A (en) * | 1991-09-23 | 1998-04-14 | Florida State University | Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them |
US6018073A (en) * | 1991-09-23 | 2000-01-25 | Florida State University | Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them |
KR960006762B1 (ko) * | 1992-02-29 | 1996-05-23 | 삼성전자주식회사 | 화상부호화를 위한 효율적인 2차원 데이타의 주사선택회로 |
FR2696454B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane. |
IL107950A (en) | 1992-12-15 | 2001-04-30 | Upjohn Co | b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them |
JPH09511212A (ja) * | 1993-06-11 | 1997-11-11 | ジ・アップジョン・カンパニー | Δ▲上6▼,▲上7▼−タキソール類の抗悪性腫瘍的使用およびそれらを含む医薬組成物 |
US5405972A (en) * | 1993-07-20 | 1995-04-11 | Florida State University | Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes |
US6005120A (en) | 1993-07-20 | 1999-12-21 | Florida State University | Tricyclic and tetracyclic taxanes |
IL127599A (en) * | 1994-01-28 | 2004-06-01 | Upjohn Co | Process for preparing isotaxol analogs |
CA2288306A1 (en) | 1997-04-28 | 1998-11-05 | Rhone-Poulenc Rorer S.A. | Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors |
FR2794771B1 (fr) | 1999-06-11 | 2001-08-10 | Aventis Pharma Sa | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
EP2480523B1 (de) * | 2009-09-23 | 2017-03-01 | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. | Verfahren zur herstellung von n-acyl-b-phenyl-alanin |
EP2753355B1 (de) | 2011-09-08 | 2018-10-24 | New York University | Onkolytisches herpes-simplex-virus und therapeutische verwendungen davon |
WO2013096455A1 (en) | 2011-12-20 | 2013-06-27 | Dana-Farber Cancer Institute, Inc. | Methods for diagnosing and treating oncogenic kras-associated cancer |
EP2855698A4 (de) | 2012-05-24 | 2016-03-30 | Dana Farber Cancer Inst Inc | Abzielung auf den glutamin-zu-pyruvat-signalweg zur behandlung von mit dem kras-onkogen assoziierten krebs |
US20150285802A1 (en) | 2012-07-18 | 2015-10-08 | Dana-Farber Cancer Institute, Inc. | Methods for treating, preventing and predicting risk of developing breast cancer |
WO2014149871A1 (en) | 2013-03-14 | 2014-09-25 | Icahn School Of Medicine At Mount Sinai | Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer |
WO2015050844A1 (en) | 2013-10-01 | 2015-04-09 | Dana-Farber Cancer Institute, Inc. | Methods of treating cancer with atovaquone-related compounds |
WO2015149006A2 (en) | 2014-03-27 | 2015-10-01 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating ncoa4-mediated autophagic targeting of ferritin |
MA39818A (fr) | 2014-03-30 | 2017-02-08 | Benevir Biopharm Inc | Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques |
EP3307330B1 (de) | 2015-06-15 | 2021-03-10 | New York University | Verfahren zur behandlung unter verwendung onkolytischer viren |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US4775782A (en) * | 1987-09-30 | 1988-10-04 | Ncr Corporation | Checkout counter with remote keyboard writing pad and display |
FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
CA2023645C (fr) * | 1989-08-23 | 2002-03-26 | Jean-Noel Denis | Procede pour la preparation enantioselective de derives de la phenylisoserine |
-
1990
- 1990-05-22 FR FR9006368A patent/FR2662440B1/fr not_active Expired - Lifetime
-
1991
- 1991-05-16 SK SK1451-91A patent/SK277925B6/sk unknown
- 1991-05-16 CZ CS911451A patent/CZ279927B6/cs unknown
- 1991-05-20 IL IL9819091A patent/IL98190A/en not_active IP Right Cessation
- 1991-05-21 WO PCT/FR1991/000406 patent/WO1991017977A1/fr active IP Right Grant
- 1991-05-21 AU AU79693/91A patent/AU648319B2/en not_active Ceased
- 1991-05-21 YU YU89691A patent/YU89691A/sh unknown
- 1991-05-21 ES ES91910270T patent/ES2057899T3/es not_active Expired - Lifetime
- 1991-05-21 HU HU9203651A patent/HU212728B/hu not_active IP Right Cessation
- 1991-05-21 IE IE173791A patent/IE64276B1/en not_active IP Right Cessation
- 1991-05-21 NZ NZ238206A patent/NZ238206A/xx unknown
- 1991-05-21 DK DK91910270.7T patent/DK0530286T3/da active
- 1991-05-21 DE DE69103265T patent/DE69103265T2/de not_active Expired - Fee Related
- 1991-05-21 AT AT91910270T patent/ATE109456T1/de not_active IP Right Cessation
- 1991-05-21 US US07/949,548 patent/US5290957A/en not_active Expired - Fee Related
- 1991-05-21 ZA ZA913828A patent/ZA913828B/xx unknown
- 1991-05-21 RU RU9192016318A patent/RU2091368C1/ru active
- 1991-05-21 CA CA002079313A patent/CA2079313A1/fr not_active Abandoned
- 1991-05-21 JP JP91509580A patent/JPH05506864A/ja active Pending
- 1991-05-21 EP EP91910270A patent/EP0530286B1/de not_active Expired - Lifetime
- 1991-05-22 PT PT97745A patent/PT97745B/pt not_active IP Right Cessation
-
1992
- 1992-10-09 FI FI924568A patent/FI924568A0/fi not_active Application Discontinuation
- 1992-11-20 NO NO924488A patent/NO179942C/no unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |