DK0530285T3 - Fremgangsmåde til enantioselektiv fremstilling af phenylisoserinderivater - Google Patents

Fremgangsmåde til enantioselektiv fremstilling af phenylisoserinderivater

Info

Publication number
DK0530285T3
DK0530285T3 DK91910265.7T DK91910265T DK0530285T3 DK 0530285 T3 DK0530285 T3 DK 0530285T3 DK 91910265 T DK91910265 T DK 91910265T DK 0530285 T3 DK0530285 T3 DK 0530285T3
Authority
DK
Denmark
Prior art keywords
pct
enantioselective preparation
phenyl isoserine
date nov
isoserine derivatives
Prior art date
Application number
DK91910265.7T
Other languages
Danish (da)
English (en)
Inventor
Arlene Correa
Jean-Noel Denis
Andrew-Elliot Greene
David Scott Grierson
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0530285T3 publication Critical patent/DK0530285T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Control Of Transmission Device (AREA)
  • Measuring Fluid Pressure (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK91910265.7T 1990-05-22 1991-05-21 Fremgangsmåde til enantioselektiv fremstilling af phenylisoserinderivater DK0530285T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9006369A FR2662441B1 (fr) 1990-05-22 1990-05-22 Procede de preparation enantioselective de derives de la phenylisoserine.

Publications (1)

Publication Number Publication Date
DK0530285T3 true DK0530285T3 (da) 1994-09-26

Family

ID=9396839

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91910265.7T DK0530285T3 (da) 1990-05-22 1991-05-21 Fremgangsmåde til enantioselektiv fremstilling af phenylisoserinderivater

Country Status (23)

Country Link
US (1) US5292921A (xx)
EP (1) EP0530285B1 (xx)
JP (1) JPH05506446A (xx)
AT (1) ATE109768T1 (xx)
AU (1) AU647490B2 (xx)
CA (1) CA2079314A1 (xx)
CZ (1) CZ280087B6 (xx)
DE (1) DE69103413T2 (xx)
DK (1) DK0530285T3 (xx)
ES (1) ES2057898T3 (xx)
FI (1) FI924569A0 (xx)
FR (1) FR2662441B1 (xx)
HU (1) HU210187B (xx)
IE (1) IE64687B1 (xx)
IL (1) IL98191A (xx)
NO (1) NO179943C (xx)
NZ (1) NZ238207A (xx)
PT (1) PT97746B (xx)
RU (1) RU2086538C1 (xx)
SK (1) SK277926B6 (xx)
WO (1) WO1991017976A1 (xx)
YU (1) YU89791A (xx)
ZA (1) ZA913827B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
FR2680506B1 (fr) * 1991-08-19 1994-09-02 Rhone Poulenc Rorer Sa Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
FR2696454B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane.
IL107950A (en) 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them
IT1261667B (it) * 1993-05-20 1996-05-29 Tassano ad attivita' antitumorale.
US5965739A (en) * 1993-06-11 1999-10-12 Pharmacia & Upjohn Company Δ6,7 -taxols antineoplastic use and pharmaceutical compositions containing them
US5405972A (en) * 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
US5767304A (en) * 1996-05-21 1998-06-16 The Scripps Research Institute Catalytic asymmetric aminohydroxylation of olefins with carbamates
JP2001523103A (ja) 1997-04-28 2001-11-20 ローヌ−プーラン・ロレ・エス・アー 腫瘍治療用血管形成アンタゴニストのアデノウイルスによる腫瘍内送達
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
FR2794771B1 (fr) * 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
US8338617B2 (en) 2004-11-19 2012-12-25 Dr. Reddy's Laboratories Limited Process for preparing oxazolidine derivatives
PL2753355T3 (pl) 2011-09-08 2019-04-30 Benevir Biopharm Inc Onkolityczny wirus opryszczki pospolitej i jego zastosowania lecznicze
WO2013096455A1 (en) 2011-12-20 2013-06-27 Dana-Farber Cancer Institute, Inc. Methods for diagnosing and treating oncogenic kras-associated cancer
AU2013266243A1 (en) 2012-05-24 2014-12-18 Beth Israel Deaconess Medical Center, Inc. Targeting the glutamine to pyruvate pathway for treatment of oncogenic Kras-associated cancer
WO2014014518A1 (en) 2012-07-18 2014-01-23 Dana-Farber Cancer Institute, Inc. Methods for treating, preventing and predicting risk of developing breast cancer
WO2014149871A1 (en) 2013-03-14 2014-09-25 Icahn School Of Medicine At Mount Sinai Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
WO2015050844A1 (en) 2013-10-01 2015-04-09 Dana-Farber Cancer Institute, Inc. Methods of treating cancer with atovaquone-related compounds
WO2015149006A2 (en) 2014-03-27 2015-10-01 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating ncoa4-mediated autophagic targeting of ferritin
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
US10967015B2 (en) 2015-06-15 2021-04-06 New York University Method of treatment using oncolytic viruses
CN106748856A (zh) * 2016-12-15 2017-05-31 河南豫辰药业股份有限公司 一种马尿酸乌洛托品中间体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3019069A1 (de) * 1979-05-24 1980-12-04 Lepetit Spa Verfahren zur herstellung eines serinderivats
JPS5829749A (ja) * 1981-08-14 1983-02-22 Hiroyuki Nohira （±）−フエニルグリシノ−ルの光学分割法
CA1228075A (en) * 1983-08-01 1987-10-13 Ryuichi Mita PROCESS FOR PRODUCTION OF .beta.-PHENYLSERINE
JPS60132935A (ja) * 1983-12-20 1985-07-16 Sumitomo Chem Co Ltd フエニルセリン誘導体及びその製造方法
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
IT1211805B (it) * 1987-09-25 1989-11-03 Sefind Srl Dispositivo agevolatore di carico a funzionamento automatico per stive di aeromobili
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol

Also Published As

Publication number Publication date
WO1991017976A1 (fr) 1991-11-28
HU9203650D0 (en) 1993-03-29
NO179943B (no) 1996-10-07
FI924569A (fi) 1992-10-09
JPH05506446A (ja) 1993-09-22
PT97746A (pt) 1992-02-28
PT97746B (pt) 1998-10-30
FR2662441B1 (fr) 1992-10-23
ES2057898T3 (es) 1994-10-16
ZA913827B (en) 1992-02-26
YU89791A (sh) 1994-01-20
NZ238207A (en) 1993-07-27
NO179943C (no) 1997-01-15
HUT62259A (en) 1993-04-28
NO924489D0 (no) 1992-11-20
DE69103413D1 (de) 1994-09-15
EP0530285A1 (fr) 1993-03-10
IL98191A (en) 1995-12-31
ATE109768T1 (de) 1994-08-15
RU2086538C1 (ru) 1997-08-10
CA2079314A1 (fr) 1991-11-23
NO924489L (no) 1992-11-20
DE69103413T2 (de) 1994-12-22
CS9101452A2 (en) 1991-12-17
HU210187B (en) 1995-02-28
CZ280087B6 (cs) 1995-10-18
SK277926B6 (en) 1995-08-09
FI924569A0 (fi) 1992-10-09
US5292921A (en) 1994-03-08
AU647490B2 (en) 1994-03-24
FR2662441A1 (fr) 1991-11-29
IE64687B1 (en) 1995-08-23
AU7972291A (en) 1991-12-10
IL98191A0 (en) 1992-06-21
IE911738A1 (en) 1991-12-04
EP0530285B1 (fr) 1994-08-10

Similar Documents

Publication Publication Date Title
DK0530285T3 (da) Fremgangsmåde til enantioselektiv fremstilling af phenylisoserinderivater
ATE12224T1 (de) Verbindungen mit antifibrinolytischer wirksamkeit.
ES2149815T3 (es) Imidazolinonas fungicidas.
NO981813L (no) Mellomprodukter til bruk ved fremstilling av taxanderivater
DK0632805T3 (da) Melaminderivater til anvendelse i behandlingen af cancer
HU9502184D0 (en) Optically active beta-aminoalkoxyborane complex
FI870460A (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-substituerade oktahydroindolizinderivat och vid foerfarandet anvaendbara mellanprodukter.
DK0754181T3 (da) Fremgangsmåde til fremstilling af 7-hydroxytaxaner
CA2027542A1 (en) Uv-absorbing cyclic enaminoketones
ATE99326T1 (de) N-phenyl-n-alkoxycarbonylalkyl-glycinamide, ihre herstellung und sie enthaltende medikamente.
AR245701A1 (es) Derivados de sulfamoilurea herbicidamente activos y formulacion herbicida que los contiene