DK0524906T3 - DNA-kodende for prolyl-endopeptidase samt dets anvendelse - Google Patents

DNA-kodende for prolyl-endopeptidase samt dets anvendelse

Info

Publication number
DK0524906T3
DK0524906T3 DK92810537T DK92810537T DK0524906T3 DK 0524906 T3 DK0524906 T3 DK 0524906T3 DK 92810537 T DK92810537 T DK 92810537T DK 92810537 T DK92810537 T DK 92810537T DK 0524906 T3 DK0524906 T3 DK 0524906T3
Authority
DK
Denmark
Prior art keywords
prolylendopeptidase
dna coding
amidated peptide
well
terminal amidated
Prior art date
Application number
DK92810537T
Other languages
Danish (da)
English (en)
Inventor
Tetsuya Dr Inaoka
Toshio Dr Kokubo
Daisuke Prof Tsuru
Tadashi Prof Yoshimoto
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929205457A external-priority patent/GB9205457D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0524906T3 publication Critical patent/DK0524906T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK92810537T 1991-07-24 1992-07-15 DNA-kodende for prolyl-endopeptidase samt dets anvendelse DK0524906T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91810595 1991-07-24
GB929205457A GB9205457D0 (en) 1992-03-12 1992-03-12 Process for production of prolylendopeptidase and use thereof

Publications (1)

Publication Number Publication Date
DK0524906T3 true DK0524906T3 (da) 2003-08-11

Family

ID=26130274

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92810537T DK0524906T3 (da) 1991-07-24 1992-07-15 DNA-kodende for prolyl-endopeptidase samt dets anvendelse

Country Status (11)

Country Link
US (1) US5521081A (es)
EP (2) EP0524906B1 (es)
JP (1) JP3401271B2 (es)
AT (2) ATE373096T1 (es)
CA (1) CA2074401A1 (es)
DE (2) DE69233710T2 (es)
DK (1) DK0524906T3 (es)
ES (2) ES2197143T3 (es)
IE (1) IE922409A1 (es)
MX (1) MX9204291A (es)
PT (2) PT524906E (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2573395A (en) * 1994-06-23 1996-01-19 Japat Ltd. Heat-stable prolylendopeptidase
SK138197A3 (en) * 1995-04-11 1998-07-08 Merck & Co Inc Bioprocess for production of dipeptide based compounds
US5807681A (en) * 1996-04-05 1998-09-15 Thomas Jefferson University Human retinoblastoma-related (pRb2/p130) genomic DNA and methods for detecting mutations therein
US20030180775A1 (en) * 1999-02-24 2003-09-25 Cold Spring Harbor Laboratory Filtered shotgun sequencing of complex eukaryotic genomes
US6875851B1 (en) * 1999-03-05 2005-04-05 University Of Georgia Research Foundation, Inc. Prolyl tripeptidyl peptidases nucleic acid of Porphyromonas gingivalis
US6485937B1 (en) 1999-10-15 2002-11-26 The Rockefeller University System for rapid generation of recombinant baculovirus-based expression vectors for silkworm larvae
US6864363B2 (en) 2000-11-08 2005-03-08 University Of Georgia Research Foundation, Inc. Dipeptidylpeptidases and methods of use
ATE266087T1 (de) 2000-12-07 2004-05-15 Dsm Ip Assets Bv Verfahren zur verhinderung oder verminderung der trübung in getränken
CN100506981C (zh) 2000-12-07 2009-07-01 Dsmip资产有限公司 富含具有羧基末端脯氨酸残基的肽的蛋白质水解产物
EP1509609B1 (en) 2002-06-04 2015-04-22 DSM IP Assets B.V. Protein hydrolysate rich in tripeptides
ES2525873T3 (es) 2002-06-07 2014-12-30 Dsm Ip Assets B.V. Método mejorado para la prevención o reducción del enturbiamiento en bebidas
RU2370279C2 (ru) 2003-09-23 2009-10-20 ДСМ Ай Пи ЭССЕТС Б.В. Применение пролинспецифичных эндопротеаз для гидролиза пептидов и белков
CA2647327C (en) 2006-07-13 2016-02-23 Dsm Ip Assets B.V. Improved brewing process
US7470670B2 (en) * 2006-10-17 2008-12-30 Sbarro Health Research Organization, Inc. Peptide inhibitors of cyclin-dependent kinase activity and uses thereof
US20090054333A1 (en) * 2006-10-17 2009-02-26 Antonio Giordano Peptide inhibitors of cyclin-dependent kinase activity and uses thereof
BR112014027861A2 (pt) 2012-05-11 2017-12-12 Novozymes As método de preparação de um mosto
CN106795520B (zh) * 2015-06-08 2020-04-21 江南大学 一种催化活性和比酶活提高的脯氨酰内肽酶突变体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865974A (en) * 1985-09-20 1989-09-12 Cetus Corporation Bacterial methionine N-terminal peptidase

Also Published As

Publication number Publication date
JPH05219962A (ja) 1993-08-31
CA2074401A1 (en) 1993-01-25
ES2197143T3 (es) 2004-01-01
IE922409A1 (en) 1993-01-27
EP0524906B1 (en) 2003-04-16
EP0967285A1 (en) 1999-12-29
DE69233710T2 (de) 2008-06-19
ATE237689T1 (de) 2003-05-15
MX9204291A (es) 1993-01-29
ATE373096T1 (de) 2007-09-15
ES2293701T3 (es) 2008-03-16
PT967285E (pt) 2007-12-21
EP0967285B1 (en) 2007-09-12
EP0524906A1 (en) 1993-01-27
PT524906E (pt) 2003-08-29
DE69233005T2 (de) 2003-12-11
DE69233710D1 (de) 2007-10-25
JP3401271B2 (ja) 2003-04-28
DE69233005D1 (de) 2003-05-22
US5521081A (en) 1996-05-28

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