DK0517757T3 - Flow-immunsensor-fremgangsmåde og apparat - Google Patents

Flow-immunsensor-fremgangsmåde og apparat

Info

Publication number
DK0517757T3
DK0517757T3 DK91904965T DK91904965T DK0517757T3 DK 0517757 T3 DK0517757 T3 DK 0517757T3 DK 91904965 T DK91904965 T DK 91904965T DK 91904965 T DK91904965 T DK 91904965T DK 0517757 T3 DK0517757 T3 DK 0517757T3
Authority
DK
Denmark
Prior art keywords
sensor method
immune sensor
flow immune
flow
sensor
Prior art date
Application number
DK91904965T
Other languages
English (en)
Inventor
Frances S Ligler
Bruce P Gaber
Anne W Kusterbeck
Gregory A Wemhoff
Original Assignee
Us Navy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Navy filed Critical Us Navy
Application granted granted Critical
Publication of DK0517757T3 publication Critical patent/DK0517757T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/80—Elimination or reduction of contamination by undersired ferments, e.g. aseptic cultivation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/804—Single cell protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Processing Of Solid Wastes (AREA)
DK91904965T 1990-02-23 1991-02-21 Flow-immunsensor-fremgangsmåde og apparat DK0517757T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/486,024 US5183740A (en) 1990-02-23 1990-02-23 Flow immunosensor method and apparatus
PCT/US1991/001050 WO1991013354A1 (en) 1990-02-23 1991-02-21 Flow immunosensor method and apparatus

Publications (1)

Publication Number Publication Date
DK0517757T3 true DK0517757T3 (da) 1999-11-15

Family

ID=23930306

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91904965T DK0517757T3 (da) 1990-02-23 1991-02-21 Flow-immunsensor-fremgangsmåde og apparat

Country Status (8)

Country Link
US (2) US5183740A (da)
EP (1) EP0517757B1 (da)
JP (1) JP3149947B2 (da)
KR (1) KR0171392B1 (da)
CA (1) CA2076748C (da)
DE (1) DE69131274T2 (da)
DK (1) DK0517757T3 (da)
WO (1) WO1991013354A1 (da)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376551A (en) * 1991-03-12 1994-12-27 University Of Utah Research Foundation Apparatus for using fluorescently labeled ligands in studying interaction of a native ligand and its receptor
ATE185424T1 (de) * 1991-07-29 1999-10-15 Serex Inc Differentielle bindungsaffinitäten und darauf beruhende dissoziationstestverfahren
US5370842A (en) * 1991-11-29 1994-12-06 Canon Kabushiki Kaisha Sample measuring device and sample measuring system
DE4208732C2 (de) * 1992-03-18 1995-04-27 Abion Ohg Einwegreaktionsgefäß für die Festphasenimmunanalytik und Verfahren zur Messung von über Immunreaktionen bestimmbaren Komponenten
DE4216696C2 (de) * 1992-04-10 1995-01-26 Deutsche Aerospace Verfahren und Vorrichtung zur Empfindlichkeits- und Selektivitätssteigerung bei Immuno-Assays, Molekül-Rezeptor-, DNA-komplementär-DNA- und Gast-Wirtsmolekül-Wechselwirkungs-Assays
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
US6664114B1 (en) 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
US5372783A (en) * 1992-08-03 1994-12-13 Sapidyne, Inc. Assay system
DE4229591C1 (de) * 1992-09-04 1994-03-24 Draegerwerk Ag Immunologisches Verfahren zur Bestimmung eines Analyten
WO1994020855A1 (en) * 1993-03-04 1994-09-15 Sapidyne, Inc. Assay flow apparatus and method
US5354654A (en) * 1993-07-16 1994-10-11 The United States Of America As Represented By The Secretary Of The Navy Lyophilized ligand-receptor complexes for assays and sensors
US5484709A (en) * 1993-09-10 1996-01-16 Ensys, Inc. Immunoassay method for detecting an immunologically non-remarkable compound, its components and a kit for use in performing the same
WO1996013521A1 (en) * 1993-09-10 1996-05-09 Ensys, Inc. An immunoassay for detecting immunologically non-remarkable compounds, its components and an immunoassay kit
DE4343842C1 (de) * 1993-12-22 1995-02-23 Draegerwerk Ag Reaktionsgefäß zur immunologischn Analytik von Aerosolen
US5731157A (en) * 1993-12-30 1998-03-24 The Procter And Gamble Company Two-site allergen immunoassay
WO1995019569A1 (en) * 1994-01-13 1995-07-20 Abion Beteiligungs- Und Verwaltungsgesellschaft Mbh Reaction columns for simultaneous multiple measurement and method
US5710009A (en) * 1994-02-17 1998-01-20 Serex, Inc. Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon
US5641624A (en) * 1994-06-02 1997-06-24 Sloan-Kettering Institute For Cancer Research Method for measuring anti-HIV-1 p24 antibody and use thereof
US6723516B1 (en) * 1995-01-31 2004-04-20 Agilent Technologies, Inc. Method for continuously detecting the presence and quantity of analytes in a flowing liquid stream
DK0821790T3 (da) * 1995-04-21 2002-05-13 Screentec B V On-line kobling mellem biokemisk detektering og kontinuerligt-flow separationsteknikker
WO1996033408A1 (en) * 1995-04-21 1996-10-24 Rijksuniversiteit Leiden On-line coupling of biochemical detection to continuous-flow separation techniques
US5994067A (en) * 1995-11-14 1999-11-30 The United States Of America As Represented By The Secretary Of The Army Method and kit for rapid detection of toxins and bacteria
US6750031B1 (en) 1996-01-11 2004-06-15 The United States Of America As Represented By The Secretary Of The Navy Displacement assay on a porous membrane
EP0879417A1 (en) * 1996-02-09 1998-11-25 Kalibrant Limited Assay apparatus
AU740812B2 (en) * 1996-03-20 2001-11-15 Serex, Inc. Chromatographic immunoassay device and method utilizing particle valency for quantitation
WO1998029730A1 (en) * 1996-12-31 1998-07-09 Rorer Pharmaceutical Products Inc. Method and apparatus for selective depletion of biological particles
US6020209A (en) 1997-04-28 2000-02-01 The United States Of America As Represented By The Secretary Of The Navy Microcapillary-based flow-through immunosensor and displacement immunoassay using the same
SE9702658D0 (sv) * 1997-07-09 1997-07-09 Thomas Carlsson Regeneration of biosensors
AU754999B2 (en) * 1998-03-10 2002-11-28 Large Scale Proteomics Corporation Detection and characterization of microorganisms
US7220596B2 (en) * 1998-04-15 2007-05-22 Utah State University Real time detection of antigens
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US6573107B1 (en) * 1998-08-05 2003-06-03 The University Of Wyoming Immunochemical detection of an explosive substance in the gas phase through surface plasmon resonance spectroscopy
US6853854B1 (en) 1998-09-18 2005-02-08 Q Step Technologies, Llc Noninvasive measurement system
US6022326A (en) * 1998-10-30 2000-02-08 Lifepoint, Inc. Device and method for automatic collection of whole saliva
JP2001004628A (ja) * 1999-06-18 2001-01-12 Kanagawa Acad Of Sci & Technol 免疫分析装置と免疫分析方法
DE60031988T2 (de) 1999-07-16 2007-06-14 The Board Of Regents Of The University Of Texas System, Austin Verfahren und vorrichtung zur zuführung von proben zu einer chemischen sensormatrix
US20020072085A1 (en) * 1999-12-15 2002-06-13 Brunner Michael S. Method and device for fluid quality measurement
ATE403145T1 (de) * 2000-01-31 2008-08-15 Univ Texas Tragbare vorrichtung mit einer sensor-array- anordnung
AU2001256695A1 (en) * 2000-05-11 2001-11-20 Matsushita Seiko Co. Ltd. Chemical sensor device
US8133698B2 (en) * 2000-05-15 2012-03-13 Silver James H Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation
US7769420B2 (en) * 2000-05-15 2010-08-03 Silver James H Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
US7006858B2 (en) 2000-05-15 2006-02-28 Silver James H Implantable, retrievable sensors and immunosensors
US6442413B1 (en) * 2000-05-15 2002-08-27 James H. Silver Implantable sensor
US7181261B2 (en) 2000-05-15 2007-02-20 Silver James H Implantable, retrievable, thrombus minimizing sensors
WO2002004950A2 (en) * 2000-07-12 2002-01-17 Werner Naser Direct assessment of analyte to reference molecule ratios
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
US20040005582A1 (en) * 2000-08-10 2004-01-08 Nanobiodynamics, Incorporated Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
CA2314398A1 (en) 2000-08-10 2002-02-10 Edward Shipwash Microarrays and microsystems for amino acid analysis and protein sequencing
US6472228B2 (en) 2000-12-04 2002-10-29 Lifepoint, Inc. Composition and methods for synthesis of novel tracers for detecting amphetamine and methamphetamine in samples
US20020197622A1 (en) * 2001-01-31 2002-12-26 Mcdevitt John T. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
US20020160363A1 (en) * 2001-01-31 2002-10-31 Mcdevitt John T. Magnetic-based placement and retention of sensor elements in a sensor array
US6720193B2 (en) 2001-02-05 2004-04-13 Board Of Regents Of The University Of Nebraska Analysis of free analyte fractions by rapid affinity chromatography
US6727104B2 (en) * 2001-02-05 2004-04-27 The Board Of Regents Of The University Of Nebraska Microcolumn chromatographic immunoassays
US20030003436A1 (en) * 2001-02-05 2003-01-02 Willson C. Grant Use of mesoscale self-assembly and recognition to effect delivery of sensing reagent for arrayed sensors
US6686209B2 (en) * 2001-03-12 2004-02-03 Lifepoint, Inc. Reagents for detecting cannabinoids
US7229835B2 (en) * 2001-10-25 2007-06-12 The University Of Maryland, Baltimore County Amine detection method and materials
US20030162308A1 (en) * 2001-12-04 2003-08-28 Dave Smith Orthogonal read assembly
CA2469464A1 (en) * 2001-12-07 2003-06-19 Dyax Corporation Method and apparatus for washing magnetically responsive particles
US7419821B2 (en) * 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
US20060134713A1 (en) * 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
WO2003090605A2 (en) 2002-04-26 2003-11-06 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
US8211657B2 (en) * 2002-04-29 2012-07-03 The Board Of Trustees Of The University Of Arkansas Capillary-column-based bioseparator/bioreactor with an optical/electrochemical detector for detection of microbial pathogens
JP2005533502A (ja) * 2002-07-24 2005-11-10 ボード オブ レジェンツ，ザ ユニバーシティー オブ テキサス システム 膜法による微生物の捕捉と検出
US8557743B2 (en) * 2002-09-05 2013-10-15 Dyax Corp. Display library process
DE10247430A1 (de) * 2002-10-11 2004-04-29 Fresenius Hemocare Gmbh Verfahren zur Bestimmung des Gehalts an Endotoxinen in Flüssigkeiten
US20040101900A1 (en) * 2002-11-25 2004-05-27 Mauro J. Mattew Assay for rapid detection of TNT
FR2847984B1 (fr) * 2002-11-28 2005-07-08 Commissariat Energie Atomique Procede de detection en continu d'un analyte, reactif trifonctionnel de detection mis en oeuvre et dispositif de detection
US7651850B2 (en) * 2003-05-16 2010-01-26 Board Of Regents, The University Of Texas System Image and part recognition technology
US9317922B2 (en) 2003-05-16 2016-04-19 Board Of Regents The University Of Texas System Image and part recognition technology
SE0301639D0 (sv) * 2003-06-06 2003-06-06 Biacore Ab Method and apparatus for characterization of intercations
US7304139B2 (en) * 2003-10-28 2007-12-04 University Of Florida Research Foundation, Inc. Polynucleotides and polypeptides of Anaplasma phagocytophilum and methods of using the same
WO2006036163A2 (en) * 2003-11-05 2006-04-06 Greg Liang Oral fluid sampling device and method
US7713748B2 (en) * 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
AU2004300168A1 (en) * 2003-12-11 2005-06-30 Board Of Regents, The University Of Texas System Method and system for the analysis of saliva using a sensor array
DE102004006470B4 (de) * 2004-02-06 2006-06-01 Senova Gesellschaft für Biowissenschaft und Technik mbH Absorptionsphotometrisches Verfahren zur quantitativen Stoffanalyse
US20060257854A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Membrane assay system including preloaded particles
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US20060257991A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US20060257941A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle and membrane sensor elements
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US7781226B2 (en) * 2004-02-27 2010-08-24 The Board Of Regents Of The University Of Texas System Particle on membrane assay system
US7435386B2 (en) * 2004-03-25 2008-10-14 The United States Of America As Represented By The Secretary Of The Navy Reagentless and reusable biosensors with tunable differential binding affinities and methods of making
US20050279413A1 (en) * 2004-06-18 2005-12-22 Der-Fan Shen Flow control switch
US8377398B2 (en) 2005-05-31 2013-02-19 The Board Of Regents Of The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
AU2006261953B2 (en) * 2005-06-24 2012-02-23 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US7749772B1 (en) 2006-06-29 2010-07-06 Varian, Inc. Antibody and immunoassays for determining the presence of Δ9-Tetrahydrocannabinol
KR100787993B1 (ko) 2006-08-22 2007-12-24 허관용 교원병 검출장치 및 항원항체복합체 검출방법
WO2008043041A1 (en) 2006-10-04 2008-04-10 University Of Washington Method and device for rapid parallel microfluidic molecular affinity assays
EP2099916A2 (en) * 2006-12-22 2009-09-16 Dow AgroSciences LLC Plant-made west nile virus (wnv) vaccines, vectors and plant codon optimized sequences
JP5169496B2 (ja) * 2008-05-30 2013-03-27 富士通株式会社 被検体の流速決定方法、ならびにその方法を用いた被検体評価方法および被検体評価装置の設計方法
US8021873B2 (en) 2008-07-16 2011-09-20 Boston Microfluidics Portable, point-of-care, user-initiated fluidic assay methods and systems
US20110117673A1 (en) * 2008-07-16 2011-05-19 Johnson Brandon T Methods and systems to collect and prepare samples, to implement, initiate and perform assays, and to control and manage fluid flow
US20110151479A1 (en) * 2008-08-25 2011-06-23 University Of Washington Microfluidic systems incorporating flow-through membranes
WO2010049010A1 (en) 2008-10-28 2010-05-06 Murauski Uladzimir A Methods and kits for detection of toxemia
US9024766B2 (en) * 2009-08-28 2015-05-05 The Invention Science Fund, Llc Beverage containers with detection capability
US8898069B2 (en) * 2009-08-28 2014-11-25 The Invention Science Fund I, Llc Devices and methods for detecting an analyte in salivary fluid
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
WO2013134742A2 (en) 2012-03-08 2013-09-12 Cyvek, Inc Micro-tube particles for microfluidic assays and methods of manufacture
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
JP5701894B2 (ja) 2009-11-23 2015-04-15 サイヴェク・インコーポレイテッド アッセイを行う方法及び装置
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US9651568B2 (en) 2009-11-23 2017-05-16 Cyvek, Inc. Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays
US8404441B2 (en) * 2010-04-19 2013-03-26 Empire Technology Development Llc DNA intercalator detection
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US9804159B2 (en) 2010-10-15 2017-10-31 Purdue Research Foundation Immunoreactive antigens of Mycoplasma haemofelis and diagnostic immunoassay
CA2830533C (en) 2011-03-22 2020-02-18 Cyvek, Inc. Microfluidic devices and methods of manufacture and use
US8968377B2 (en) 2011-05-09 2015-03-03 The Invention Science Fund I, Llc Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
US9238133B2 (en) 2011-05-09 2016-01-19 The Invention Science Fund I, Llc Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
EP2817626B1 (en) 2012-02-20 2017-09-27 Uladzimir A. Murauski Methods for detection of active malignancy
US9804109B2 (en) * 2012-05-10 2017-10-31 Design West Technologies, Inc. System and method for chemical and/or biological detection
US9791376B2 (en) * 2012-06-12 2017-10-17 Panasonic Intellectual Property Management Co., Ltd. Optical sensor
US20160258945A1 (en) * 2013-10-21 2016-09-08 Northeastern University Point-of-care immunosensing device for multi-biomarker detection
WO2015187289A1 (en) 2014-06-03 2015-12-10 Pop Test Abuse Deterrent Technology Llc Drug device configured for wireless communication
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
US10330617B2 (en) 2017-01-10 2019-06-25 Design West Technologies, Inc. Wearable sensor badge for toxic industrial chemicals
EP4089401A1 (de) * 2021-05-10 2022-11-16 Siemens Aktiengesellschaft Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz
CN113758886B (zh) * 2021-08-05 2022-08-23 华中农业大学 一种基于乳胶微球浓度变化的多目标物同时检测方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264327A (en) * 1978-04-21 1981-04-28 Blum Alvin S Method and apparatus for automatic competitive binding analysis
US4277560A (en) * 1978-10-24 1981-07-07 Technicon Instruments Corporation Enzyme immunoassays using immobilized reagents in a flowing stream
US4582809A (en) * 1982-06-14 1986-04-15 Myron J. Block Apparatus including optical fiber for fluorescence immunoassay
US4895809A (en) * 1984-01-09 1990-01-23 Varian Associates, Inc. Immobilized antigen-antibody displacement process
US4803170A (en) * 1985-05-09 1989-02-07 Ultra Diagnostics Corporation Competitive immunoassay method, device and test kit
FR2585367B1 (fr) * 1985-07-26 1987-10-02 Lyonnaise Eaux Procede de dosage immunologique en continu de composes organiques dans un fluide en circulation, et dispositif de mise en oeuvre
IL82873A0 (en) * 1987-06-15 1987-12-20 Orgenics Ltd Reversed competitive solid phase immunoassay for detecting single epitope analytes and kit therefor
IT1223295B (it) * 1987-08-14 1990-09-19 Boehringer Biochemia Srl Dispositivo e metodo immunodiagnostico
US5045479A (en) 1988-07-05 1991-09-03 The Johns Hopkins University Continuous flow competitive assay with reference system
US4884469A (en) * 1989-04-28 1989-12-05 Detroit Marine Engineering Corporation Steering wheel

Also Published As

Publication number Publication date
CA2076748A1 (en) 1991-08-24
JPH05504625A (ja) 1993-07-15
WO1991013354A1 (en) 1991-09-05
CA2076748C (en) 2004-01-20
JP3149947B2 (ja) 2001-03-26
EP0517757A1 (en) 1992-12-16
EP0517757A4 (en) 1993-10-20
EP0517757B1 (en) 1999-05-26
KR0171392B1 (ko) 1999-05-15
DE69131274T2 (de) 1999-12-16
US5183740A (en) 1993-02-02
US6245296B1 (en) 2001-06-12
DE69131274D1 (de) 1999-07-01

Similar Documents

Publication Publication Date Title
DK0517757T3 (da) Flow-immunsensor-fremgangsmåde og apparat
DK0560959T3 (da) Fremgangsmåde og apparat til ekshalationsanalyse
EP0449582A3 (en) Measuring method and apparatus
DK0613652T3 (da) Apparat og fremgangsmåde til ikke invasiv måling af oxygenmåling
EP0454166A3 (en) Traffic flow measuring method and apparatus
DK0385805T3 (da) Fremgangsmåde og apparat til signalbehandling
DK512484A (da) Apparat og fremgangsmaade til mikrobiel patogen detektering
NO940846D0 (no) Fremgangsmåte og apparat for effektmåling
DE69133480D1 (de) Bildverarbeitungsverfahren und -vorrichtung
NO941283L (no) Apparat og fremgangsmåte for belegging av partikler
DK0398017T3 (da) Fremgangsmåde til udtagning af fiskeindvolde og apparat til udøvelse af fremgangsmåden
EP0460471A3 (en) Method and apparatus for measuring cross-toe
NO912886L (no) Fremgangsmaate og apparat for fremstilling av tertiaere alkyletere.
GB9119503D0 (en) Inspection method and apparatus
DK0477796T3 (da) Fremgangsmåde og apparat til beregning af termisk følsomhed
DK0514222T3 (da) Fremgangsmåde og apparat til kommunikation
GB2243692B (en) Method and apparatus for processing mass air flow sensor signals
NO992258D0 (no) Anordning og fremgangsmÕte for signalbehandling
DK0476692T3 (da) Fremgangsmåde og apparat til beregning af forudbestemt middeltermisk sensitivitet
EP0445675A3 (en) Method and apparatus for continuous flow analysis
EP0442116A3 (en) Pipeline method and apparatus
DK0476691T3 (da) Fremgangsmåde og apparat til beregning af termisk følsomhed
NO170175C (no) Fremgangsmaate og apparat for maaling av fluidstroemning
NO960007D0 (no) Apparat og fremgangsmåte for måling av strömningsmengde
NO894782D0 (no) Fremgangsmaate og apparat for visuell sammenligning.